Towards fair and clinically relevant polygenic predictions.
Trends in genetics : TIG
| Authors | |
| Keywords | |
| Abstract | Lennon et al. recently proposed a clinical polygenic score (PGS) pipeline as part of the Electronic Medical Records and Genomics (eMERGE) network initiative. In this spotlight article we discuss the broader context for the use of PGS in preventive medicine and highlight key limitations and challenges facing their inclusion in prediction models. |
| Year of Publication | 2024
|
| Journal | Trends in genetics : TIG
|
| Date Published | 04/2024
|
| ISSN | 0168-9525
|
| DOI | 10.1016/j.tig.2024.04.002
|
| PubMed ID | 38643035
|
| Links |