A YAC contig map of the human genome.

Nature

Authors	I Chumakov P Rigault I Le Gall C Bellanné-Chantelot A Billault S Guillou P Soularue G Guasconi E Poullier I Gros
Keywords	Humans Genetic Markers Chromosome Mapping Nucleic Acid Hybridization DNA Fingerprinting In Situ Hybridization, Fluorescence Genome, Human Sequence Tagged Sites Chromosomes, Artificial, Yeast
Abstract	A yeast artificial chromosome library containing 33,000 clones with an average insert size of one megabase of human genomic DNA was extensively analysed by several different procedures for detecting overlaps and positional information. We developed an analysis strategy that resulted, after confirmatory tests, in a YAC contig map reliably covering about 75% of the human genome in 225 contigs having an average size of about ten megabases.
Year of Publication	1995
Journal	Nature
Volume	377
Issue	6547 Suppl
Pages	175-297
Date Published	1995 Sep 28
ISSN	0028-0836
DOI	10.1038/377175a0
PubMed ID	7566096
Links	PubMed DOI Google Scholar

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