Take DAT, Flu!

Immunity
Authors
Keywords
Abstract

Some microbial metabolites can be immunomodulatory, but there is limited understanding of how these contribute to inter-individual variation in response to infection. In a recent study in Science, Steed et al. (2017) show that the bacterial metabolite desaminotyrosine (DAT) increases type I interferon expression, resulting in an improved immune response to influenza infection.

Year of Publication
2017
Journal
Immunity
Volume
47
Issue
3
Pages
400-402
Date Published
2017 09 19
ISSN
1097-4180
DOI
10.1016/j.immuni.2017.09.002
PubMed ID
28930655
Links