MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.

Genomics
Authors
Keywords
Abstract

With the advent of RFLPs, genetic linkage maps are now being assembled for a number of organisms including both inbred experimental populations such as maize and outbred natural populations such as humans. Accurate construction of such genetic maps requires multipoint linkage analysis of particular types of pedigrees. We describe here a computer package, called MAPMAKER, designed specifically for this purpose. The program uses an efficient algorithm that allows simultaneous multipoint analysis of any number of loci. MAPMAKER also includes an interactive command language that makes it easy for a geneticist to explore linkage data. MAPMAKER has been applied to the construction of linkage maps in a number of organisms, including the human and several plants, and we outline the mapping strategies that have been used.

Year of Publication
1987
Journal
Genomics
Volume
1
Issue
2
Pages
174-81
Date Published
1987 Oct
ISSN
0888-7543
PubMed ID
3692487
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