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J Infect Dis DOI:10.1093/infdis/jiw190

Ebola Virus Epidemiology and Evolution in Nigeria.

Publication TypeJournal Article
Year of Publication2016
AuthorsFolarin, OA, Ehichioya, D, Schaffner, SF, Winnicki, SM, Wohl, S, Eromon, P, West, KL, Gladden-Young, A, Oyejide, NE, Matranga, CB, Deme, ABineta, James, A, Tomkins-Tinch, C, Onyewurunwa, K, Ladner, JT, Palacios, G, Nosamiefan, I, Andersen, KG, Omilabu, S, Park, DJ, Yozwiak, NL, Nasidi, A, Garry, RF, Tomori, O, Sabeti, PC, Happi, CT
JournalJ Infect Dis
Date Published2016 Jul 4

Containment limited the 2014 Nigerian Ebola virus (EBOV) disease outbreak to 20 reported cases and 8 fatalities. We present here clinical data and contact information for at least 19 case patients, and full-length EBOV genome sequences for 12 of the 20. The detailed contact data permits nearly complete reconstruction of the transmission tree for the outbreak. The EBOV genomic data are consistent with that tree. It confirms that there was a single source for the Nigerian infections, shows that the Nigerian EBOV lineage nests within a lineage previously seen in Liberia but is genetically distinct from it, and supports the conclusion that transmission from Nigeria to elsewhere did not occur.


Alternate JournalJ. Infect. Dis.
PubMed ID27377746
Grant ListU01 HG007480 / HG / NHGRI NIH HHS / United States
U19 AI110818 / AI / NIAID NIH HHS / United States