Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets.

Gastroenterology
Authors
Werna Venema
Michiel Voskuil
Arnau Vila
Gerben van der Vries
Bernadien Jansen
Bana Jabri
Klaas Faber
Gerard Dijkstra
Ramnik Xavier
Cisca Wijmenga
Daniel Graham
Rinse Weersma
Eleonora Festen
Keywords
Female
Humans
Male
Adult
T-Lymphocytes
Middle Aged
Treatment Outcome
Cohort Studies
Genome-Wide Association Study
Crohn Disease
Cells, Cultured
Sequence Analysis, RNA
Molecular Targeted Therapy
Intestinal Mucosa
Ileum
Collagenases
Edetic Acid
Year of Publication
2019
Journal
Gastroenterology
Volume
156
Issue
3
Pages
812-815.e22
Date Published
2019 Feb
ISSN
1528-0012
DOI
10.1053/j.gastro.2018.10.046
PubMed ID
30391472
PubMed Central ID
PMC6759855
Links
Grant list
P30 DK042086 / DK / NIDDK NIH HHS / United States
RC2 DK114784 / DK / NIDDK NIH HHS / United States

Recent Broad Publications