The new era of quantitative cell imaging-challenges and opportunities.

Mol Cell
Authors
Keywords
Abstract

Quantitative optical microscopy-an emerging, transformative approach to single-cell biology-has seen dramatic methodological advancements over the past few years. However, its impact has been hampered by challenges in the areas of data generation, management, and analysis. Here we outline these technical and cultural challenges and provide our perspective on the trajectory of this field, ushering in a new era of quantitative, data-driven microscopy. We also contrast it to the three decades of enormous advances in the field of genomics that have significantly enhanced the reproducibility and wider adoption of a plethora of genomic approaches.

Year of Publication
2022
Journal
Mol Cell
Volume
82
Issue
2
Pages
241-247
Date Published
2022 01 20
ISSN
1097-4164
DOI
10.1016/j.molcel.2021.12.024
PubMed ID
35063094
Links
Grant list
R35 GM122547 / GM / NIGMS NIH HHS / United States