Taking on the Elephant in the Tissue Culture Room: iPSC Modeling for Sporadic ALS.

Cell Stem Cell
Authors
Keywords
Abstract

Modeling ALS remains a major challenge since the vast majority of cases are sporadic. Recently in Nature Medicine, Fujimori et al. leverage genetic heterogeneity and define subgroups of iPSC-derived motor neurons using multiplex phenotypic profiles, and thus make substantial progress toward robust modeling of both familial and sporadic ALS.

Year of Publication
2018
Journal
Cell Stem Cell
Volume
23
Issue
4
Pages
466-467
Date Published
2018 10 04
ISSN
1875-9777
DOI
10.1016/j.stem.2018.09.015
PubMed ID
30290176
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