Effective Reserve: A Latent Variable to Improve Outcome Prediction in Stroke.
Prediction of functional outcome after stroke based on initial presentation remains an open challenge, suggesting that an important aspect is missing from these prediction models. There exists the notion of a protective mechanism called brain reserve, which may be utilized to understand variations in disease outcome. In this work, we expand the concept of brain reserve (effective reserve) to improve prediction models of functional outcome after acute ischemic stroke (AIS). Consecutive AIS patients with acute brain magnetic resonance imaging (
|Year of Publication||
J Stroke Cerebrovasc Dis
|PubMed Central ID||
K23 NS064052 / NS / NINDS NIH HHS / United States
R01 NS082285 / NS / NINDS NIH HHS / United States
R01 NS086905 / NS / NINDS NIH HHS / United States