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Dev Cell DOI:10.1016/j.devcel.2016.07.006

Microglia: Phagocytosing to Clear, Sculpt, and Eliminate.

Publication TypeJournal Article
Year of Publication2016
AuthorsHong, S, Stevens, B
JournalDev Cell
Volume38
Issue2
Pages126-8
Date Published2016 Jul 25
ISSN1878-1551
KeywordsAnimals, Brain, Humans, Microglia, Neurons, Phagocytosis, Synapses
Abstract

Microglia are the primary phagocytes of the central nervous system. They eliminate excess functional connections between neurons to sculpt neuronal circuits during development and throughout adulthood. Understanding how microglia recognize and prune synapses during development is providing insight into synapse loss and dysfunction in disease.

DOI10.1016/j.devcel.2016.07.006
Pubmed

http://www.ncbi.nlm.nih.gov/pubmed/27459063?dopt=Abstract

Alternate JournalDev. Cell
PubMed ID27459063