Microglia: Phagocytosing to Clear, Sculpt, and Eliminate.

Dev Cell
Authors
Keywords
Abstract

Microglia are the primary phagocytes of the central nervous system. They eliminate excess functional connections between neurons to sculpt neuronal circuits during development and throughout adulthood. Understanding how microglia recognize and prune synapses during development is providing insight into synapse loss and dysfunction in disease.

Year of Publication
2016
Journal
Dev Cell
Volume
38
Issue
2
Pages
126-8
Date Published
2016 Jul 25
ISSN
1878-1551
DOI
10.1016/j.devcel.2016.07.006
PubMed ID
27459063
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