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  • Showing 1-17 of 17 Results
2014
Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth.Stanley, SA, Barczak AK, Silvis MR, Luo SS, Sogi K., Vokes M., Bray MA, Carpenter AE, Moore CB, Siddiqi N., Rubin EJ, and Hung DT PLoS pathogens, 2014/02/01, Volume 10, Issue 2, p.e1003946, (2014) Read More / View Supplemental Materials
Abstract
2013
Bacterial toxins and small molecules elucidate endosomal trafficking.Slater, LH, Clatworthy AE, and Hung DT Trends in microbiology, 2013/12/23, (2013) Read More / View Supplemental Materials
Abstract
Synthesis and structure-activity relationships of phenyl-substituted coumarins with anti-tubercular activity that target FadD32.Kawate, T., Iwase N., Shimizu M., Stanley SA, Wellington S., Kazyanskaya E., and Hung DT Bioorganic & medicinal chemistry letters, 2013/11/15, Volume 23, Issue 22, p.6052-9, (2013) Read More / View Supplemental Materials
Abstract
Identification of Novel Inhibitors of Nonreplicating Mycobacterium tuberculosis Using a Carbon Starvation Model.Grant, SS, Kawate T., Nag PP, Silvis MR, Gordon K., Stanley SA, Kazyanskaya E., Nietupski R., Golas A., FitzGerald M., Cho S., Franzblau SG, and Hung DT ACS chemical biology, 2013/08/13, (2013) Read More / View Supplemental Materials
Abstract
Diarylcoumarins inhibit mycolic acid biosynthesis and kill Mycobacterium tuberculosis by targeting FadD32.Stanley, SA, Kawate T., Iwase N., Shimizu M., Clatworthy AE, Kazyanskaya E., Sacchettini JC, Ioerger TR, Siddiqi NA, Minami S., Aquadro JA, Schmidt Grant S., Rubin EJ, and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2013/07/09, Volume 110, Issue 28, p.11565-70, (2013) Read More / View Supplemental Materials
Abstract
Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis.Hett, EC, Slater LH, Mark KG, Kawate T., Monks BG, Stutz A., Latz E., and Hung DT Nature chemical biology, 2013/06/01, Volume 9, Issue 6, p.398-405, (2013) Read More / View Supplemental Materials
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Persistent bacterial infections, antibiotic tolerance, and the oxidative stress response.Grant, SS, and Hung DT Virulence, 2013/04/05, Volume 4, Issue 4, (2013) Read More / View Supplemental Materials
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2012
Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals.Grant, SS, Kaufmann BB, Chand NS, Haseley N., and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2012/07/24, Volume 109, Issue 30, p.12147-52, (2012) Read More / View Supplemental Materials
Abstract
Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening.Stanley, SA, Grant SS, Kawate T., Iwase N., Shimizu M., Wivagg C., Silvis M., Kazyanskaya E., Aquadro J., Golas A., FitzGerald M., Dai H., Zhang L., and Hung DT ACS chemical biology, 2012/05/21, (2012) Read More / View Supplemental Materials
Abstract
RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities.Barczak, AK, Gomez JE, Kaufmann BB, Hinson ER, Cosimi L., Borowsky ML, Onderdonk AB, Stanley SA, Kaur D., Bryant KF, Knipe DM, Sloutsky A., and Hung DT Proceedings of the National Academy of Sciences of the United States of America, 2012/04/17, Volume 109, Issue 16, p.6217-22, (2012) Read More / View Supplemental Materials
Abstract
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.Grad, YH, Lipsitch M., Feldgarden M., Arachchi HM, Cerqueira GC, FitzGerald M., Godfrey P., Haas BJ, Murphy CI, Russ C., Sykes S., Walker BJ, Wortman JR, Young S., Zeng Q., Abouelleil A., Bochicchio J., Chauvin S., Desmet T., Gujja S., et al. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.3065-70, (2012) Read More / View Supplemental Materials
Abstract
2011
The two-component sensor kinase KinB acts as a non-canonical switch between acute and chronic infection.Chand, NS, and Hung DT Virulence, 2011/11/01, Volume 2, Issue 6, p.553-8, (2011) Read More / View Supplemental Materials
Abstract
Probing bacterial pathogenesis with genetics, genomics, and chemical biology: past, present, and future approaches.Gomez, JE, Clatworthy A., and Hung DT Critical reviews in biochemistry and molecular biology, 2011/02/01, Volume 46, Issue 1, p.41-66, (2011) Read More / View Supplemental Materials
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2010
The fast track to multidrug resistance.Kaufmann, BB, and Hung DT Molecular cell, 2010/02/12, Volume 37, Issue 3, p.297-8, (2010) Read More / View Supplemental Materials
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2009
Toward a systems-level analysis of infection biology: a new method for conducting genetic screens in human cells.Stanley, SA, and Hung DT Science translational medicine, 2009/12/16, Volume 1, Issue 11, p.11ps13, (2009) Read More / View Supplemental Materials
Abstract
Chemical tools for dissecting bacterial physiology and virulence.Stanley, SA, and Hung DT Biochemistry, 2009/09/22, Volume 48, Issue 37, p.8776-86, (2009) Read More / View Supplemental Materials
Abstract
Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing.Nusbaum, C., Ohsumi TK, Gomez J., Aquadro J., Victor TC, Warren RM, Hung DT, Birren BW, Lander E. S., and Jaffe DB Nature methods, 2009/01/01, Volume 6, Issue 1, p.67-9, (2009) Read More / View Supplemental Materials
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  • Showing 1-17 of 17 Results