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  • Showing 1-12 of 12 Results
2016
Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk.Lassen, KG, McKenzie CI, Mari M., Murano T., Begun J., Baxt LA, Goel G., Villablanca EJ, Kuo SY, Huang H., Macia L., Bhan AK, Batten M., Daly M. J., Reggiori F., Mackay CR, and Xavier RJ Immunity, 2016/06/06, (2016) Read More / View Supplemental Materials
Abstract
Mechanisms of Pediatric Inflammatory Bowel Disease.Peloquin, JM, Goel G., Villablanca EJ, and Xavier RJ Annual review of immunology, 2016/05/20, Volume 34, p.31-64, (2016) Read More / View Supplemental Materials
Abstract
New Regulatory Roles of Galectin-3 in the High-affinity IgE Receptor Signaling.Bambouskova, M., Polakovicova I., Halova I., Goel G., Draberova L., Bugajev V., Doan A., Utekal P., Gardet A., Xavier RJ, and Draber P. Molecular and cellular biology, 2016/02/29, (2016) Read More / View Supplemental Materials
Abstract
2015
Functional genomics identifies negative regulatory nodes controlling phagocyte oxidative burst.Graham, DB, Becker CE, Doan A., Goel G., Villablanca EJ, Knights D., Mok A., Ng AC, Doench JG, Root DE, Clish CB, and Xavier RJ Nature communications, 2015/07/21, Volume 6, p.7838, (2015) Read More / View Supplemental Materials
Abstract
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.Kuo, SY, Castoreno AB, Aldrich LN, Lassen KG, Goel G., Dančík V., Kuballa P., Latorre I., Conway KL, Sarkar S., Maetzel D., Jaenisch R., Clemons PA, Schreiber SL, Shamji AF, and Xavier RJ Proceedings of the National Academy of Sciences of the United States of America, 2015/07/20, (2015) Read More / View Supplemental Materials
Abstract
Integrated Genomics of Crohn's Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy.Begun, J., Lassen KG, Jijon HB, Baxt LA, Goel G., Heath RJ, Ng A., Tam JM, Kuo SY, Villablanca EJ, Fagbami L., Oosting M., Kumar V., Schenone M., Carr SA, Joosten LA, Vyas JM, Daly M. J., Netea MG, Brown GD, et al. Cell reports, 2015/06/30, Volume 11, Issue 12, p.1905-18, (2015) Read More / View Supplemental Materials
Abstract
The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells.Khor, B., Gagnon JD, Goel G., Roche MI, Conway KL, Tran K., Aldrich LN, Sundberg TB, Paterson AM, Mordecai S., Dombkowski D., Schirmer M., Tan PH, Bhan AK, Roychoudhuri R., Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, et al. eLife, 2015/05/22, Volume 4, (2015) Read More / View Supplemental Materials
Abstract
Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages.Palsson-McDermott, EM, Curtis AM, Goel G., Lauterbach MA, Sheedy FJ, Gleeson LE, van den Bosch MW, Quinn SR, Domingo-Fernandez R., Johnson DG, Jiang JK, Israelsen WJ, Keane J., Thomas C., Clish C., Vanden Heiden M., Xavier RJ, and O'Neill LA Cell metabolism, 2015/01/06, Volume 21, Issue 1, p.65-80, (2015) Read More / View Supplemental Materials
Abstract
2014
Multivariate inference of pathway activity in host immunity and response to therapeutics.Goel, G., Conway KL, Jaeger M., Netea MG, and Xavier RJ Nucleic acids research, 2014/08/21, (2014) Read More / View Supplemental Materials
Abstract
An Image-Based Genetic Assay Identifies Genes in T1D Susceptibility Loci Controlling Cellular Antiviral Immunity in Mouse.Liao, J., Jijon HB, Kim IR, Goel G., Doan A., Sokol H., Bauer H., Herrmann BG, Lassen KG, and Xavier RJ PloS one, 2014/01/01, Volume 9, Issue 9, p.e108777, (2014) Read More / View Supplemental Materials
Abstract
2013
Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection.Conway, KL, Kuballa P., Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M., Aldrich LN, Villablanca EJ, Peloquin JM, Goel G., Lee IA, Mizoguchi E., Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, et al. Gastroenterology, 2013/08/21, (2013) Read More / View Supplemental Materials
Abstract
2012
p40phox expression regulates neutrophil recruitment and function during the resolution phase of intestinal inflammation.Conway, KL, Goel G., Sokol H., Manocha M., Mizoguchi E., Terhorst C., Bhan AK, Gardet A., and Xavier RJ Journal of immunology (Baltimore, Md. : 1950), 2012/10/01, Volume 189, Issue 7, p.3631-40, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-12 of 12 Results