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  • Showing 1-9 of 9 Results
2016
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.Prins, BP, Abbasi A., Wong A., Vaez A., Nolte I., Franceschini N., Stuart PE, Guterriez Achury J., Mistry V., Bradfield JP, Valdes AM, Bras J., Shatunov A., PAGE Consortium, International Stroke Genetics Consortium, consortium Systemic Sclerosis, consortium Treat OA, DIAGRAM Consortium, CARDIOGRAMplusC4D Consortium, consortium ALS, et al. PLoS medicine, 2016/06/01, Volume 13, Issue 6, p.e1001976, (2016) Read More / View Supplemental Materials
Abstract
A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases.Han, B., Pouget JG, Slowikowski K., Stahl E., Lee CH, Diogo D., Hu X., Park YR, Kim E., Gregersen PK, Dahlqvist SR, Worthington J., Martin J., Eyre S., Klareskog L., Huizinga T., Chen WM, Onengut-Gumuscu S., Rich SS, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, et al. Nature genetics, 2016/05/16, (2016) Read More / View Supplemental Materials
Abstract
Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population.Robinson, EB, St Pourcain B., Anttila V., Kosmicki JA, Bulik-Sullivan B., Grove J., Maller J., Samocha KE, Sanders SJ, Ripke S., Martin J., Hollegaard MV, Werge T., Hougaard DM, iPSYCH-SSI-Broad Autism Group, Neale BM, Evans DM, Skuse D., Mortensen PB, Børglum AD, et al. Nature genetics, 2016/03/21, (2016) Read More / View Supplemental Materials
Abstract
2015
Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014.Aas, M., Blokland GA, Chawner SJ, Choi SW, Estrada J., Forsingdal A., Friedrich M., Ganesham S., Hall L., Haslinger D., Huckins L., Loken E., Malan-Müller S., Martin J., Misiewicz Z., Pagliaroli L., Pardiñas AF, Pisanu C., Quadri G., Santoro ML, et al. Psychiatric genetics, 2015/11/12, (2015) Read More / View Supplemental Materials
Abstract
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases.Lenz, TL, Deutsch AJ, Han B., Hu X., Okada Y., Eyre S., Knapp M., Zhernakova A., Huizinga TW, Abecasis G., Becker J., Boeckxstaens GE, Chen WM, Franke A., Gladman DD, Gockel I., Gutierrez-Achury J., Martin J., Nair RP, Nöthen MM, et al. Nature genetics, 2015/08/10, (2015) Read More / View Supplemental Materials
Abstract
TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits.Diogo, D., Bastarache L., Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S., Bowes J., Cui J., Lee A., Pappas DA, Kremer JM, Barton A., Coenen MJ, Franke B., Kiemeney LA, Mariette X., Richard-Miceli C., Canhão H., Fonseca JE, et al. PloS one, 2015/01/01, Volume 10, Issue 4, p.e0122271, (2015) Read More / View Supplemental Materials
Abstract
2014
Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity.Han, B., Diogo D., Eyre S., Kallberg H., Zhernakova A., Bowes J., Padyukov L., Okada Y., González-Gay MA, Rantapää-Dahlqvist S., Martin J., Huizinga TW, Plenge RM, Worthington J., Gregersen PK, Klareskog L., de Bakker PI, and Raychaudhuri S. American journal of human genetics, 2014/04/03, Volume 94, Issue 4, p.522-32, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Rare, Low-Frequency, and Common Variants in the Protein-Coding Sequence of Biological Candidate Genes from GWASs Contribute to Risk of Rheumatoid Arthritis.Diogo, D., Kurreeman F., Stahl EA, Liao KP, Gupta N., Greenberg JD, Rivas MA, Hickey B., Flannick J., Thomson B., Guiducci C., Ripke S., Adzhubey I., Barton A., Kremer JM, Alfredsson L., Consortium of Rheumatology Researchers of North America, Rheumatoid Arthritis Consortium International, Sunyaev S., Martin J., et al. American journal of human genetics, 2013/01/10, Volume 92, Issue 1, p.15-27, (2013) Read More / View Supplemental Materials
Abstract
  • Showing 1-9 of 9 Results