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2015
An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis.Birsoy, K., Wang T., Chen WW, Freinkman E., Abu-Remaileh M., and Sabatini DM Cell, 2015/07/30, Volume 162, Issue 3, p.540-51, (2015) Read More / View Supplemental Materials
Abstract
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.Kim, D., Fiske BP, Birsoy K., Freinkman E., Kami K., Possemato RL, Chudnovsky Y., Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M., Ramkissoon SH, Ligon KL, Kang SW, Snuderl M., Vander Heiden MG, and Sabatini DM Nature, 2015/04/16, Volume 520, Issue 7547, p.363-7, (2015) Read More / View Supplemental Materials
Abstract
2014
Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition.Shaul, YD, Freinkman E., Comb WC, Cantor JR, Tam WL, Thiru P., Kim D., Kanarek N., Pacold ME, Chen WW, Bierie B., Possemato R., Reinhardt F., Weinberg R. A., Yaffe MB, and Sabatini DM Cell, 2014/08/28, Volume 158, Issue 5, p.1094-109, (2014) Read More / View Supplemental Materials
Abstract
Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells.Chen, WW, Birsoy K., Mihaylova MM, Snitkin H., Stasinski I., Yucel B., Bayraktar EC, Carette JE, Clish CB, Brummelkamp TR, Sabatini DD, and Sabatini DM Cell reports, 2014/04/10, Volume 7, Issue 1, p.27-34, (2014) Read More / View Supplemental Materials
Abstract
Metabolic determinants of cancer cell sensitivity to glucose limitation and biguanides.Birsoy, K., Possemato R., Lorbeer FK, Bayraktar EC, Thiru P., Yucel B., Wang T., Chen WW, Clish CB, and Sabatini DM Nature, 2014/04/03, Volume 508, Issue 7494, p.108-12, (2014) Read More / View Supplemental Materials
Abstract
2013
MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors.Birsoy, K., Wang T., Possemato R., Yilmaz OH, Koch CE, Chen WW, Hutchins AW, Gultekin Y., Peterson TR, Carette JE, Brummelkamp TR, Clish CB, and Sabatini DM Nature genetics, 2013/01/01, Volume 45, Issue 1, p.104-8, (2013) Read More / View Supplemental Materials
Abstract
  • Showing 1-6 of 6 Results