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  • Showing 1-6 of 6 Results
2016
Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.Wagner, FF, Weïwer M., Steinbacher S., Schomburg A., Reinemer P., Gale JP, Campbell AJ, Fisher SL, Zhao WN, Reis SA, Hennig KM, Thomas M., Müller P., Jefson MR, Fass DM, Haggarty SJ, Zhang YL, and Holson EB Bioorganic & medicinal chemistry, 2016/09/15, Volume 24, Issue 18, p.4008-15, (2016) Read More / View Supplemental Materials
Abstract
G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.Kedersha, N., Panas MD, Achorn CA, Lyons S., Tisdale S., Hickman T., Thomas M., Lieberman J., McInerney GM, Ivanov P., and Anderson P. The Journal of cell biology, 2016/03/28, Volume 212, Issue 7, p.845-60, (2016) Read More / View Supplemental Materials
Abstract
Health and population effects of rare gene knockouts in adult humans with related parents.Narasimhan, VM, Hunt KA, Mason D., Baker CL, Karczewski KJ, Barnes MR, Barnett AH, Bates C., Bellary S., Bockett NA, Giorda K., Griffiths CJ, Hemingway H., Jia Z., Kelly MA, Khawaja HA, Lek M., McCarthy S., McEachan R., O'Donnell-Luria A., et al. Science (New York, N.Y.), 2016/03/03, (2016) Read More / View Supplemental Materials
Abstract
2015
Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers.Wagner, FF, Zhang YL, Fass DM, Joseph N., Gale JP, Weïwer M., McCarren P., Fisher SL, Kaya T., Zhao WN, Reis SA, Hennig KM, Thomas M., Lemercier BC, Lewis MC, Guan JS, Moyer MP, Scolnick E., Haggarty SJ, Tsai LH, et al. Chemical science (Royal Society of Chemistry : 2010), 2015/01/01, Volume 6, Issue 1, p.804-815, (2015) Read More / View Supplemental Materials
Abstract
2013
Potent and Selective Inhibition of Histone Deacetylase 6 (HDAC6) Does Not Require a Surface-Binding Motif.Wagner, FF, Olson DE, Gale JP, Kaya T., Weïwer M., Aidoud N., Thomas M., Davoine EL, Lemercier BC, Zhang YL, and Holson EB Journal of medicinal chemistry, 2013/02/18, (2013) Read More / View Supplemental Materials
Abstract
2012
Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries.Lowe, JT, Lee MD 4th, Akella LB, Davoine E., Donckele EJ, Durak L., Duvall JR, Gerard B., Holson EB, Joliton A., Kesavan S., Lemercier BC, Liu H., Marié JC, Mulrooney CA, Muncipinto G., Welzel-O'Shea M., Panko LM, Rowley A., Suh BC, et al. The Journal of organic chemistry, 2012/08/10, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-6 of 6 Results