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2015
Cas9 gRNA engineering for genome editing, activation and repression.Kiani, S., Chavez A., Tuttle M., Hall RN, Chari R., Ter-Ovanesyan D., Qian J., Pruitt BW, Beal J., Vora S., Buchthal J., Kowal EJ, Ebrahimkhani MR, Collins JJ, Weiss R., and Church G. Nature methods, 2015/09/07, (2015) Read More / View Supplemental Materials
Abstract
2014
Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells.Yang, L., Grishin D., Wang G., Aach J., Zhang CZ, Chari R., Homsy J., Cai X., Zhao Y., Fan JB, Seidman C., Seidman J., Pu W., and Church G. Nature communications, 2014/11/26, Volume 5, p.5507, (2014) Read More / View Supplemental Materials
Abstract
2012
Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers.Briggs, AW, Rios X., Chari R., Yang L., Zhang F., Mali P., and Church GM Nucleic acids research, 2012/06/26, (2012) Read More / View Supplemental Materials
Abstract
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