Scientific Publications

Search by Keyword(s)
Found 18 results

Filters: Author is Okada, Y  [Clear All Filters]

Search Results

  • Showing 1-18 of 18 Results
2015
New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.Lee, SH, Byrne EM, Hultman CM, Kähler A., Vinkhuyzen AA, Ripke S., Andreassen OA, Frisell T., Gusev A., Hu X., Karlsson R., Mantzioris VX, McGrath JJ, Mehta D., Stahl EA, Zhao Q., Kendler KS, Sullivan PF, Price AL, O'Donovan M., et al. International journal of epidemiology, 2015/08/18, (2015) Read More / View Supplemental Materials
Abstract
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases.Lenz, TL, Deutsch AJ, Han B., Hu X., Okada Y., Eyre S., Knapp M., Zhernakova A., Huizinga TW, Abecasis G., Becker J., Boeckxstaens GE, Chen WM, Franke A., Gladman DD, Gockel I., Gutierrez-Achury J., Martin J., Nair RP, Nöthen MM, et al. Nature genetics, 2015/08/10, (2015) Read More / View Supplemental Materials
Abstract
Directional dominance on stature and cognition in diverse human populations.Joshi, PK, Esko T., Mattsson H., Eklund N., Gandin I., Nutile T., Jackson AU, Schurmann C., Smith AV, Zhang W., Okada Y., Stančáková A., Faul JD, Zhao W., Bartz TM, Concas MP, Franceschini N., Enroth S., Vitart V., Trompet S., et al. Nature, 2015/07/01, (2015) Read More / View Supplemental Materials
Abstract
Interactions between amino-acid-defined MHC class II variants and smoking for seropositive rheumatoid arthritis.Kim, K., Jiang X., Cui J., Lu B., Costenbader KH, Sparks JA, Bang SY, Lee HS, Okada Y., Raychaudhuri S., Alfredsson L., Bae SC, Klareskog L., and Karlson EW Arthritis & rheumatology (Hoboken, N.J.), 2015/06/22, (2015) Read More / View Supplemental Materials
Abstract
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy.Liu, H., Irwanto A., Fu X., Yu G., Yu Y., Sun Y., Wang C., Wang Z., Okada Y., Low H., Li Y., Liany H., Chen M., Bao F., Li J., You J., Zhang Q., Liu J., Chu T., Andiappan AK, et al. Nature genetics, 2015/02/02, (2015) Read More / View Supplemental Materials
Abstract
TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits.Diogo, D., Bastarache L., Liao KP, Graham RR, Fulton RS, Greenberg JD, Eyre S., Bowes J., Cui J., Lee A., Pappas DA, Kremer JM, Barton A., Coenen MJ, Franke B., Kiemeney LA, Mariette X., Richard-Miceli C., Canhão H., Fonseca JE, et al. PloS one, 2015/01/01, Volume 10, Issue 4, p.e0122271, (2015) Read More / View Supplemental Materials
Abstract
2014
The HLA-DRβ1 amino acid positions 11-13-26 explain the majority of SLE-MHC associations.Kim, K., Bang SY, Lee HS, Okada Y., Han B., Saw WY, Teo YY, and Bae SC Nature communications, 2014/12/23, Volume 5, p.5902, (2014) Read More / View Supplemental Materials
Abstract
A role for noncoding variation in schizophrenia.Roussos, P., Mitchell AC, Voloudakis G., Fullard JF, Pothula VM, Tsang J., Stahl EA, Georgakopoulos A., Ruderfer DM, Charney A., Okada Y., Siminovitch KA, Worthington J., Padyukov L., Klareskog L., Gregersen PK, Plenge RM, Raychaudhuri S., Fromer M., Purcell SM, et al. Cell reports, 2014/11/20, Volume 9, Issue 4, p.1417-29, (2014) Read More / View Supplemental Materials
Abstract
Variation at HLA-DRB1 is associated with resistance to enteric fever.Dunstan, SJ, Hue NT, Han B., Li Z., Tram TT, Sim KS, Parry CM, Chinh NT, Vinh H., Lan NP, Thieu NT, Vinh PV, Koirala S., Dongol S., Arjyal A., Karkey A., Shilpakar O., Dolecek C., Foo JN, Phuong LT, et al. Nature genetics, 2014/11/10, (2014) Read More / View Supplemental Materials
Abstract
Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes.Okada, Y., Han B., Tsoi LC, Stuart PE, Ellinghaus E., Tejasvi T., Chandran V., Pellett F., Pollock R., Bowcock AM, Krueger GG, Weichenthal M., Voorhees JJ, Rahman P., Gregersen PK, Franke A., Nair RP, Abecasis GR, Gladman DD, Elder JT, et al. American journal of human genetics, 2014/08/07, Volume 95, Issue 2, p.162-72, (2014) Read More / View Supplemental Materials
Abstract
Risk for ACPA-positive rheumatoid arthritis is driven by shared HLA amino acid polymorphisms in Asian and European populations.Okada, Y., Kim K., Han B., Pillai NE, Ong RT, Saw WY, Luo M., Jiang L., Yin J., Bang SY, Lee HS, Brown MA, Bae SC, Xu H., Teo YY, de Bakker PI, and Raychaudhuri S. Human molecular genetics, 2014/07/28, (2014) Read More / View Supplemental Materials
Abstract
Fine Mapping Seronegative and Seropositive Rheumatoid Arthritis to Shared and Distinct HLA Alleles by Adjusting for the Effects of Heterogeneity.Han, B., Diogo D., Eyre S., Kallberg H., Zhernakova A., Bowes J., Padyukov L., Okada Y., González-Gay MA, Rantapää-Dahlqvist S., Martin J., Huizinga TW, Plenge RM, Worthington J., Gregersen PK, Klareskog L., de Bakker PI, and Raychaudhuri S. American journal of human genetics, 2014/04/03, Volume 94, Issue 4, p.522-32, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide association studies to advance our understanding of critical cell types and pathways in rheumatoid arthritis: recent findings and challenges.Diogo, D., Okada Y., and Plenge RM Current opinion in rheumatology, 2014/01/01, Volume 26, Issue 1, p.85-92, (2014) Read More / View Supplemental Materials
Abstract
Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene.Okada, Y., Diogo D., Greenberg JD, Mouassess F., Achkar WA, Fulton RS, Denny JC, Gupta N., Mirel D., Gabriel S., Li G., Kremer JM, Pappas DA, Carroll RJ, Eyler AE, Trynka G., Stahl EA, Cui J., Saxena R., Coenen MJ, et al. PloS one, 2014/01/01, Volume 9, Issue 2, p.e87645, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Entering the age of whole-exome sequencing in rheumatic diseases: Novel insights into disease pathogenicity.Okada, Y., and Plenge RM Arthritis and rheumatism, 2013/05/10, (2013) Read More / View Supplemental Materials
2012
Use of a Multiethnic Approach to Identify Rheumatoid- Arthritis-Susceptibility Loci, 1p36 and 17q12.Kurreeman, FA, Stahl EA, Okada Y., Liao K., Diogo D., Raychaudhuri S., Freudenberg J., Kochi Y., Patsopoulos NA, Gupta N., investigators CLEAR, Sandor C., Bang SY, Lee HS, Padyukov L., Suzuki A., Siminovitch K., Worthington J., Gregersen PK, Hughes LB, et al. American journal of human genetics, 2012/03/09, Volume 90, Issue 3, p.524-532, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-18 of 18 Results