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  • Showing 1-18 of 18 Results
2016
A pleiotropic missense variant in SLC39A8 is associated with Crohn's disease and human gut microbiome composition.Li, D., Achkar JP, Haritunians T., Jacobs JP, Hui KY, D'Amato M., Brand S., Radford-Smith G., Halfvarson J., Niess JH, Kugathasan S., Büning C., Schumm LP, Klei L., Ananthakrishnan A., Aumais G., Baidoo L., Dubinsky M., Fiocchi C., Glas J., et al. Gastroenterology, 2016/08/01, (2016) Read More / View Supplemental Materials
Abstract
A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GMCSF.Chuang, LS, Villaverde N., Hui KY, Mortha A., Rahman A., Levine AP, Haritunians T., Ng SM, Zhang W., Hsu NY, Facey JA, Luong T., Fernandez-Hernandez H., Li D., Rivas M., Schiff ER, Gusev A., Schumm LP, Bowen BM, Sharma Y., et al. Gastroenterology, 2016/07/01, (2016) Read More / View Supplemental Materials
Abstract
Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study.Prins, BP, Abbasi A., Wong A., Vaez A., Nolte I., Franceschini N., Stuart PE, Guterriez Achury J., Mistry V., Bradfield JP, Valdes AM, Bras J., Shatunov A., PAGE Consortium, International Stroke Genetics Consortium, consortium Systemic Sclerosis, consortium Treat OA, DIAGRAM Consortium, CARDIOGRAMplusC4D Consortium, consortium ALS, et al. PLoS medicine, 2016/06/01, Volume 13, Issue 6, p.e1001976, (2016) Read More / View Supplemental Materials
Abstract
CSF1R mosaicism in a family with hereditary diffuse leukoencephalopathy with spheroids.Eichler, FS, Li J., Guo Y., Caruso PA, Bjonnes AC, Pan J., Booker JK, Lane JM, Tare A., Vlasac I., Hakonarson H., Gusella JF, Zhang J., Keating BJ, and Saxena R. Brain : a journal of neurology, 2016/05/05, (2016) Read More / View Supplemental Materials
Abstract
Causal Assessment of Serum Urate Levels in Cardiometabolic Diseases Through a Mendelian Randomization Study.Keenan, T., Zhao W., Rasheed A., Ho WK, Malik R., Felix JF, Young R., Shah N., Samuel M., Sheikh N., Mucksavage ML, Shah O., Li J., Morley M., Laser A., Mallick NH, Zaman KS, Ishaq M., Rasheed SZ, Memon FU, et al. Journal of the American College of Cardiology, 2016/02/02, Volume 67, Issue 4, p.407-16, (2016) Read More / View Supplemental Materials
Abstract
2015
Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index.Felix, JF, Bradfield JP, Monnereau C., van der Valk RJ, Stergiakouli E., Chesi A., Gaillard R., Feenstra B., Thiering E., Kreiner-Møller E., Mahajan A., Pitkänen N., Joro R., Cavadino A., Huikari V., Franks S., Groen-Blokhuis MM, Cousminer DL, Marsh JA, Lehtimäki T., et al. Human molecular genetics, 2015/11/24, (2015) Read More / View Supplemental Materials
Abstract
Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study.Cleynen, I., Boucher G., Jostins L., Schumm LP, Zeissig S., Ahmad T., Andersen V., Andrews JM, Annese V., Brand S., Brant SR, Cho JH, Daly M. J., Dubinsky M., Duerr RH, Ferguson LR, Franke A., Gearry RB, Goyette P., Hakonarson H., et al. Lancet (London, England), 2015/10/16, (2015) Read More / View Supplemental Materials
Abstract
Concept and design of a genome-wide association genotyping array tailored for transplantation-specific studies.Li, YR, van Setten J., Verma SS, Lu Y., Holmes MV, Gao H., Lek M., Nair N., Chandrupatla H., Chang B., Karczewski KJ, Wong C., Mohebnasab M., Mukhtar E., Phillips R., Tragante V., Hou C., Steel L., Lee T., Garifallou J., et al. Genome medicine, 2015/10/01, Volume 7, Issue 1, p.90, (2015) Read More / View Supplemental Materials
Abstract
Directional dominance on stature and cognition in diverse human populations.Joshi, PK, Esko T., Mattsson H., Eklund N., Gandin I., Nutile T., Jackson AU, Schurmann C., Smith AV, Zhang W., Okada Y., Stančáková A., Faul JD, Zhao W., Bartz TM, Concas MP, Franceschini N., Enroth S., Vitart V., Trompet S., et al. Nature, 2015/07/01, (2015) Read More / View Supplemental Materials
Abstract
Contribution of common non-synonymous variants in PCSK1 to body-mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331,175 individuals.Nead, KT, Li A., Wehner MR, Neupane B., Gustafsson S., Butterworth A., Engert JC, Davis AD, Hegele RA, Miller R., den Hoed M., Khaw KT, Kilpeläinen TO, Wareham N., Edwards TL, Hallmans G., Varga TV, Kardia SL, Smith JA, Zhao W., et al. Human molecular genetics, 2015/03/17, (2015) Read More / View Supplemental Materials
Abstract
2014
A novel common variant in DCST2 is associated with length in early life and height in adulthood.van der Valk, RJ, Kreiner-Møller E., Kooijman MN, Guxens M., Stergiakouli E., Sääf A., Bradfield JP, Geller F., Hayes MG, Cousminer DL, Körner A., Thiering E., Curtin JA, Myhre R., Huikari V., Joro R., Kerkhof M., Warrington NM, Pitkänen N., Ntalla I., et al. Human molecular genetics, 2014/10/03, (2014) Read More / View Supplemental Materials
Abstract
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials.Swerdlow, DI, Preiss D., Kuchenbaecker KB, Holmes MV, Engmann JE, Shah T., Sofat R., Stender S., Johnson PC, Scott RA, Leusink M., Verweij N., Sharp SJ, Guo Y., Giambartolomei C., Chung C., Peasey A., Amuzu A., Li K., Palmen J., et al. Lancet, 2014/09/24, (2014) Read More / View Supplemental Materials
Abstract
Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease: A Genome-Wide Association Study.Naj, AC, Jun G., Reitz C., Kunkle BW, Perry W., Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E., Barmada MM, et al. JAMA neurology, 2014/09/08, (2014) Read More / View Supplemental Materials
Abstract
The genetic architecture of pediatric cognitive abilities in the Philadelphia Neurodevelopmental Cohort.Robinson, EB, Kirby A., Ruparel K., Yang J., McGrath L., Anttila V., Neale BM, Merikangas K., Lehner T., Sleiman PM, Daly M. J., Gur R., Gur R., and Hakonarson H. Molecular psychiatry, 2014/07/15, (2014) Read More / View Supplemental Materials
Abstract
Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci.Tragante, V., Barnes MR, Ganesh SK, Lanktree MB, Guo W., Franceschini N., Smith EN, Johnson T., Holmes MV, Padmanabhan S., Karczewski KJ, Almoguera B., Barnard J., Baumert J., Chang YP, Elbers CC, Farrall M., Fischer ME, Gaunt TR, Gho JM, et al. American journal of human genetics, 2014/02/19, (2014) Read More / View Supplemental Materials
Abstract
Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.Escott-Price, V., Bellenguez C., Wang LS, Choi SH, Harold D., Jones L., Holmans P., Gerrish A., Vedernikov A., Richards A., Destefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R., Jun G., Bis JC, Beecham GW, Grenier-Boley B., Russo G., et al. PloS one, 2014/01/01, Volume 9, Issue 6, p.e94661, (2014) Read More / View Supplemental Materials
Abstract
2012
Phasing of many thousands of genotyped samples.Williams, AL, Patterson N., Glessner J., Hakonarson H., and Reich D. American journal of human genetics, 2012/08/10, Volume 91, Issue 2, p.238-51, (2012) Read More / View Supplemental Materials
Abstract
Large-Scale Gene-Centric Meta-Analysis across 39 Studies Identifies Type 2 Diabetes Loci.Saxena, R., Elbers CC, Guo Y., Peter I., Gaunt TR, Mega JL, Lanktree MB, Tare A., Castillo BA, Li YR, Johnson T., Bruinenberg M., Gilbert-Diamond D., Rajagopalan R., Voight BF, Balasubramanyam A., Barnard J., Bauer F., Baumert J., Bhangale T., et al. American journal of human genetics, 2012/03/09, Volume 90, Issue 3, p.410-425, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-18 of 18 Results