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  • Showing 1-7 of 7 Results
2016
Novel diversity-oriented synthesis-derived respiratory syncytial virus inhibitors identified via a high throughput replicon-based screen.Duvall, JR, VerPlank L., Ludeke B., McLeod SM, Lee MD 4th, Vishwanathan K., Mulrooney CA, le Quement S., Yu Q., Palmer MA, Fleming P., Fearns R., Foley MA, and Scherer CA Antiviral research, 2016/04/05, (2016) Read More / View Supplemental Materials
Abstract
High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.Plouffe, DM, Wree M., Du AY, Meister S., Li F., Patra K., Lubar A., Okitsu SL, Flannery EL, Kato N., Tanaseichuk O., Comer E., Zhou B., Kuhen K., Zhou Y., Leroy D., Schreiber SL, Scherer CA, Vinetz J., and Winzeler EA Cell host & microbe, 2016/01/13, Volume 19, Issue 1, p.114-26, (2016) Read More / View Supplemental Materials
Abstract
2015
Development and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity.Nühs, A., De Rycker M., Manthri S., Comer E., Scherer CA, Schreiber SL, Ioset JR, and Gray DW PLoS neglected tropical diseases, 2015/09/01, Volume 9, Issue 9, p.e0004094, (2015) Read More / View Supplemental Materials
Abstract
2014
Diversity-Oriented Synthesis probe targets Plasmodium falciparum cytochrome b ubiquinone reduction site and synergizes with oxidation site inhibitors.Lukens, AK, Heidebrecht RW Jr, Mulrooney C., Beaudoin JA, Comer E., Duvall JR, Fitzgerald ME, Masi D., Galinsky K., Scherer CA, Palmer M., Munoz B., Foley M., Schreiber SL, Wiegand RC, and Wirth DF The Journal of infectious diseases, 2014/10/21, (2014) Read More / View Supplemental Materials
Abstract
2012
A Potent and Selective Quinoxalinone-Based STK33 Inhibitor Does Not Show Synthetic Lethality in KRAS-Dependent Cells.Weïwer, M., Spoonamore J., Wei J., Guichard B., Ross NT, Masson K., Silkworth W., Dandapani S., Palmer M., Scherer CA, Stern AM, Schreiber SL, and Munoz B. ACS medicinal chemistry letters, 2012/12/13, Volume 3, Issue 12, p.1034-1038, (2012) Read More / View Supplemental Materials
Abstract
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.Wen, Q., Goldenson B., Silver SJ, Schenone M., Dancik V., Huang Z., Wang LZ, Lewis TA, An WF, Li X., Bray MA, Thiollier C., Diebold L., Gilles L., Vokes MS, Moore CB, Bliss-Moreau M., VerPlank L., Tolliday NJ, Mishra R., et al. Cell, 2012/08/03, Volume 150, Issue 3, p.575-89, (2012) Read More / View Supplemental Materials
Abstract
STK33 kinase inhibitor BRD-8899 has no effect on KRAS-dependent cancer cell viability.Luo, T., Masson K., Jaffe JD, Silkworth W., Ross NT, Scherer CA, Scholl C., Fröhling S., Carr SA, Stern AM, Schreiber SL, and Golub T. R. Proceedings of the National Academy of Sciences of the United States of America, 2012/02/21, Volume 109, Issue 8, p.2860-5, (2012) Read More / View Supplemental Materials
Abstract
  • Showing 1-7 of 7 Results