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2016
Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.Dirice, E., Walpita D., Vetere A., Meier BC, Kahraman S., Hu J., Dančík V., Burns SM, Gilbert TJ, Olson DE, Clemons PA, Kulkarni RN, and Wagner BK Diabetes, 2016/06/01, Volume 65, Issue 6, p.1660-71, (2016) Read More / View Supplemental Materials
Abstract
An Isochemogenic Set of Inhibitors To Define the Therapeutic Potential of Histone Deacetylases in β-Cell Protection.Wagner, FF, Lundh M., Kaya T., McCarren P., Zhang YL, Chattopadhyay S., Gale JP, Galbo T., Fisher SL, Meier BC, Vetere A., Richardson S., Morgan NG, Christensen DP, Gilbert TJ, Hooker JM, Leroy M., Walpita D., Mandrup-Poulsen T., Wagner BK, et al. ACS chemical biology, 2016/02/19, Volume 11, Issue 2, p.363-74, (2016) Read More / View Supplemental Materials
Abstract
2015
Kinase-Independent Small-Molecule Inhibition of JAK-STAT Signaling.Chou, DH, Vetere A., Choudhary A., Scully SS, Schenone M., Tang A., Gomez R., Burns SM, Lundh M., Vital T., Comer E., Faloon PW, Dančík V., Ciarlo C., Paulk J., Dai M., Reddy C., Sun H., Young M., Donato N., et al. Journal of the American Chemical Society, 2015/06/24, Volume 137, Issue 24, p.7929-34, (2015) Read More / View Supplemental Materials
Abstract
Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.Chattopadhyay, S., Stewart AL, Mukherjee S., Huang C., Hartwell KA, Miller PG, Subramanian R., Carmody LC, Yusuf RZ, Sykes DB, Paulk J., Vetere A., Vallet S., Santo L., Cirstea DD, Hideshima T., Dančík V., Majireck MM, Hussain MM, Singh S., et al. Cell reports, 2015/02/04, (2015) Read More / View Supplemental Materials
Abstract
High-throughput luminescent reporter of insulin secretion for discovering regulators of pancreatic Beta-cell function.Burns, SM, Vetere A., Walpita D., Dančík V., Khodier C., Perez J., Clemons PA, Wagner BK, and Altshuler D. Cell metabolism, 2015/01/06, Volume 21, Issue 1, p.126-37, (2015) Read More / View Supplemental Materials
Abstract
2014
Targeting the pancreatic β-cell to treat diabetes.Vetere, A., Choudhary A., Burns SM, and Wagner BK Nature reviews. Drug discovery, 2014/02/14, (2014) Read More / View Supplemental Materials
Abstract
2012
Chemical Methods to Induce Beta-Cell Proliferation.Vetere, A., and Wagner BK International journal of endocrinology, 2012/01/01, Volume 2012, p.925143, (2012) Read More / View Supplemental Materials
Abstract
Correction: GW8510 Increases Insulin Expression in Pancreatic Alpha Cells through Activation of p53 Transcriptional Activity.Fomina-Yadlin, D., Kubicek S., Vetere A., Hu He KH, Schreiber SL, and Wagner BK PloS one, 2012/01/01, Volume 7, Issue 3, (2012) Read More / View Supplemental Materials
Abstract
GW8510 increases insulin expression in pancreatic alpha cells through activation of p53 transcriptional activity.Fomina-Yadlin, D., Kubicek S., Vetere A., He KH, Schreiber SL, and Wagner BK PloS one, 2012/01/01, Volume 7, Issue 1, p.e28808, (2012) Read More / View Supplemental Materials
Abstract
2011
A Human Islet Cell Culture System for High-Throughput Screening.Walpita, D., Hasaka T., Spoonamore J., Vetere A., Takane KK, Fomina-Yadlin D., Fiaschi-Taesch N., Shamji A., Clemons PA, Stewart AF, Schreiber SL, and Wagner BK Journal of biomolecular screening, 2011/12/07, (2011) Read More / View Supplemental Materials
Abstract
  • Showing 1-10 of 10 Results