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  • Showing 1-14 of 14 Results
2015
Calibrating genomic and allelic coverage bias in single-cell sequencing.Zhang, CZ, Adalsteinsson VA, Francis J., Cornils H., Jung J., Maire C., Ligon KL, Meyerson M., and Love JC Nature communications, 2015/04/16, Volume 6, p.6822, (2015) Read More / View Supplemental Materials
Abstract
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.Kim, D., Fiske BP, Birsoy K., Freinkman E., Kami K., Possemato RL, Chudnovsky Y., Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M., Ramkissoon SH, Ligon KL, Kang SW, Snuderl M., Vander Heiden MG, and Sabatini DM Nature, 2015/04/16, Volume 520, Issue 7547, p.363-7, (2015) Read More / View Supplemental Materials
Abstract
Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype.Bergthold, G., Bandopadhayay P., Hoshida Y., Ramkissoon S., Ramkissoon L., Rich B., Maire CL, Paolella BR, Schumacher SE, Tabak B., Ferrer-Luna R., Ozek M., Sav A., Santagata S., Wen PY, Goumnerova LC, Ligon AH, Stiles C., Segal R., Golub T., et al. Neuro-oncology, 2015/03/29, (2015) Read More / View Supplemental Materials
Abstract
Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma.Ramkissoon, SH, Bi WL, Schumacher SE, Ramkissoon LA, Haidar S., Knoff D., Dubuc A., Brown L., Burns M., Cryan JB, Abedalthagafi M., Kang YJ, Schultz N., Reardon DA, Lee EQ, Rinne ML, Norden AD, Nayak L., Ruland S., Doherty LM, et al. Neuro-oncology, 2015/03/09, (2015) Read More / View Supplemental Materials
Abstract
Intermediate DNA methylation is a conserved signature of genome regulation.Elliott, G., Hong C., Xing X., Zhou X., Li D., Coarfa C., Bell RJ, Maire CL, Ligon KL, Sigaroudinia M., Gascard P., Tlsty TD, Harris RA, Schalkwyk LC, Bilenky M., Mill J., Farnham PJ, Kellis M., Marra MA, Milosavljevic A., et al. Nature communications, 2015/02/18, Volume 6, p.6363, (2015) Read More / View Supplemental Materials
Abstract
2014
Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma.Du, Z., Abedalthagafi M., Aizer AA, McHenry AR, Sun HH, Bray MA, Viramontes O., Machaidze R., Brastianos PK, Reardon DA, Dunn IF, Freeman GJ, Ligon KL, Carpenter AE, Alexander BM, Agar NY, Rodig SJ, Bradshaw EM, and Santagata S. Oncotarget, 2014/12/31, (2014) Read More / View Supplemental Materials
Abstract
Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5.Abedalthagafi, MS, Merrill PH, Bi WL, Jones RT, Listewnik ML, Ramkissoon SH, Thorner AR, Dunn IF, Beroukhim R., Alexander BM, Brastianos PK, Francis JM, Folkerth RD, Ligon KL, Van Hummelen P., Ligon AH, and Santagata S. Oncotarget, 2014/09/25, (2014) Read More / View Supplemental Materials
Abstract
SOX2 and p63 colocalize at genetic loci in squamous cell carcinomas.Watanabe, H., Ma Q., Peng S., Adelmant G., Swain D., Song W., Fox C., Francis JM, Pedamallu CS, Deluca DS, Brooks AN, Wang S., Que J., Rustgi AK, Wong KK, Ligon KL, Liu XS, Marto JA, Meyerson M., and Bass AJ The Journal of clinical investigation, 2014/04/01, Volume 124, Issue 4, p.1636-45, (2014) Read More / View Supplemental Materials
Abstract
Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.Brastianos, PK, Taylor-Weiner A., Manley PE, Jones RT, Dias-Santagata D., Thorner AR, Lawrence MS, Rodriguez FJ, Bernardo LA, Schubert L., Sunkavalli A., Shillingford N., Calicchio ML, Lidov HG, Taha H., Martinez-Lage M., Santi M., Storm PB, Lee JY, Palmer JN, et al. Nature genetics, 2014/02/01, Volume 46, Issue 2, p.161-5, (2014) Read More / View Supplemental Materials
Abstract
ZFHX4 Interacts with the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State.Chudnovsky, Y., Kim D., Zheng S., Whyte WA, Bansal M., Bray MA, Gopal S., Theisen MA, Bilodeau S., Thiru P., Muffat J., Yilmaz OH, Mitalipova M., Woolard K., Lee J., Nishimura R., Sakata N., Fine HA, Carpenter AE, Silver SJ, et al. Cell reports, 2014/01/15, (2014) Read More / View Supplemental Materials
Abstract
2013
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.Ramkissoon, LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A., Lawrence MS, Bergthold G., Brastianos PK, Tabak B., Ducar MD, Van Hummelen P., Macconaill LE, Pouissant-Young T., Cho YJ, Taha H., Mahmoud M., Bowers DC, Margraf L., et al. Proceedings of the National Academy of Sciences of the United States of America, 2013/05/14, Volume 110, Issue 20, p.8188-93, (2013) Read More / View Supplemental Materials
Abstract
Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.Brastianos, PK, Horowitz PM, Santagata S., Jones RT, McKenna A., Getz G., Ligon KL, Palescandolo E., Van Hummelen P., Ducar MD, Raza A., Macconaill LE, Louis DN, Hahn WC, Dunn IF, and Beroukhim R. Nature genetics, 2013/01/20, (2013) Read More / View Supplemental Materials
Abstract
2012
Integrative functional genomics identifies RINT1 as a novel GBM oncogene.Quayle, SN, Chheda MG, Shukla SA, Wiedemeyer R., Tamayo P., Dewan RW, Zhuang L., Huang-Hobbs E., Haidar S., Xiao Y., Ligon KL, Hahn WC, and Chin L. Neuro-oncology, 2012/10/16, (2012) Read More / View Supplemental Materials
Abstract
2007
Semiautomated multiplexed quantum dot-based in situ hybridization and spectral deconvolution.Byers, RJ, Di Vizio D., O'connell F., Tholouli E., Levenson RM, Gossage K., Twomey D., Yang Y., Benedettini E., Rose J., Ligon KL, Finn SP, Golub T. R., and Loda M. The Journal of molecular diagnostics : JMD, 2007/02/01, Volume 9, Issue 1, p.20-9, (2007) Read More / View Supplemental Materials
Abstract
  • Showing 1-14 of 14 Results