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  • Showing 1-11 of 11 Results
2016
Circulating Metabolites and Survival Among Patients With Pancreatic Cancer.Yuan, C., Clish CB, Wu C., Mayers JR, Kraft P., Townsend MK, Zhang M., Tworoger SS, Bao Y., Qian ZR, Rubinson DA, Ng K., Giovannucci EL, Ogino S., Stampfer MJ, Gaziano JM, Ma J., Sesso HD, Anderson GL, Cochrane BB, et al. Journal of the National Cancer Institute, 2016/06/01, Volume 108, Issue 6, (2016) Read More / View Supplemental Materials
Abstract
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer.Davidson, SM, Papagiannakopoulos T., Olenchock BA, Heyman JE, Keibler MA, Luengo A., Bauer MR, Jha AK, O'Brien JP, Pierce KA, Gui DY, Sullivan LB, Wasylenko TM, Subbaraj L., Chin CR, Stephanopolous G., Mott BT, Jacks T., Clish CB, and Vander Heiden MG Cell metabolism, 2016/02/03, (2016) Read More / View Supplemental Materials
Abstract
2015
A roadmap for interpreting (13)C metabolite labeling patterns from cells.Buescher, JM, Antoniewicz MR, Boros LG, Burgess SC, Brunengraber H., Clish CB, DeBerardinis RJ, Feron O., Frezza C., Ghesquiere B., Gottlieb E., Hiller K., Jones RG, Kamphorst JJ, Kibbey RG, Kimmelman AC, Locasale JW, Lunt SY, Maddocks OD, Malloy C., et al. Current opinion in biotechnology, 2015/08/01, Volume 34, p.189-201, (2015) Read More / View Supplemental Materials
Abstract
SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.Kim, D., Fiske BP, Birsoy K., Freinkman E., Kami K., Possemato RL, Chudnovsky Y., Pacold ME, Chen WW, Cantor JR, Shelton LM, Gui DY, Kwon M., Ramkissoon SH, Ligon KL, Kang SW, Snuderl M., Vander Heiden MG, and Sabatini DM Nature, 2015/04/16, Volume 520, Issue 7547, p.363-7, (2015) Read More / View Supplemental Materials
Abstract
Famine versus feast: understanding the metabolism of tumors in vivo.Mayers, JR, and Vander Heiden MG Trends in biochemical sciences, 2015/01/29, (2015) Read More / View Supplemental Materials
Abstract
An epitope tag alters phosphoglycerate dehydrogenase structure and impairs ability to support cell proliferation.Mattaini, KR, Brignole EJ, Kini M., Davidson SM, Fiske BP, Drennan CL, and Vander Heiden MG Cancer & metabolism, 2015/01/01, Volume 3, p.5, (2015) Read More / View Supplemental Materials
Abstract
2014
Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development.Mayers, JR, Wu C., Clish CB, Kraft P., Torrence ME, Fiske BP, Yuan C., Bao Y., Townsend MK, Tworoger SS, Davidson SM, Papagiannakopoulos T., Yang A., Dayton TL, Ogino S., Stampfer MJ, Giovannucci EL, Qian ZR, Rubinson DA, Ma J., et al. Nature medicine, 2014/10/01, Volume 20, Issue 10, p.1193-8, (2014) Read More / View Supplemental Materials
Abstract
Cell-state-specific metabolic dependency in hematopoiesis and leukemogenesis.Wang, YH, Israelsen WJ, Lee D., Yu VW, Jeanson NT, Clish CB, Cantley LC, Vander Heiden MG, and Scadden DT Cell, 2014/09/11, Volume 158, Issue 6, p.1309-23, (2014) Read More / View Supplemental Materials
Abstract
2013
PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells.Israelsen, WJ, Dayton TL, Davidson SM, Fiske BP, Hosios AM, Bellinger G., Li J., Yu Y., Sasaki M., Horner JW, Burga LN, Xie J., Jurczak MJ, Depinho RA, Clish CB, Jacks T., Kibbey RG, Wulf GM, Di Vizio D., Mills GB, et al. Cell, 2013/10/10, Volume 155, Issue 2, p.397-409, (2013) Read More / View Supplemental Materials
Abstract
2010
Activation of a metabolic gene regulatory network downstream of mTOR complex 1.Düvel, K., Yecies JL, Menon S., Raman P., Lipovsky AI, Souza AL, Triantafellow E., Ma Q., Gorski R., Cleaver S., Vander Heiden MG, MacKeigan JP, Finan PM, Clish CB, Murphy LO, and Manning BD Molecular cell, 2010/07/30, Volume 39, Issue 2, p.171-83, (2010) Read More / View Supplemental Materials
Abstract
2008
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth.Christofk, HR, Vander Heiden MG, Harris MH, Ramanathan A., Gerszten RE, Wei R., Fleming MD, Schreiber SL, and Cantley LC Nature, 2008/03/13, Volume 452, Issue 7184, p.230-3, (2008) Read More / View Supplemental Materials
Abstract
  • Showing 1-11 of 11 Results