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2016
CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo.Wang, X., Raghavan A., Chen T., Qiao L., Zhang Y., Ding Q., and Musunuru K. Arteriosclerosis, thrombosis, and vascular biology, 2016/03/03, (2016) Read More / View Supplemental Materials
Abstract
Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma.Chen, F., Zhang Y., Şenbabaoğlu Y., Ciriello G., Yang L., Reznik E., Shuch B., Micevic G., De Velasco G., Shinbrot E., Noble MS, Lu Y., Covington KR, Xi L., Drummond JA, Muzny D., Kang H., Lee J., Tamboli P., Reuter V., et al. Cell reports, 2016/03/02, (2016) Read More / View Supplemental Materials
Abstract
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.Kilpeläinen, TO, Carli JF, Skowronski AA, Sun Q., Kriebel J., Feitosa MF, Hedman Å. K., Drong AW, Hayes JE, Zhao J., Pers TH, Schick U., Grarup N., Kutalik Z., Trompet S., Mangino M., Kristiansson K., Beekman M., Lyytikäinen LP, Eriksson J., et al. Nature communications, 2016/02/01, Volume 7, p.10494, (2016) Read More / View Supplemental Materials
Abstract
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).Klionsky, DJ, Abdelmohsen K., Abe A., Abedin MJ, Abeliovich H., Acevedo Arozena A., Adachi H., Adams CM, Adams PD, Adeli K., Adhihetty PJ, Adler SG, Agam G., Agarwal R., Aghi MK, Agnello M., Agostinis P., Aguilar PV, Aguirre-Ghiso J., Airoldi EM, et al. Autophagy, 2016/01/02, Volume 12, Issue 1, p.1-222, (2016) Read More / View Supplemental Materials
2015
Definitive Localization of Intracellular Proteins: Novel Approach Using CRISPR-Cas9 Genome Editing, with Glucose 6-Phosphate Dehydrogenase as a Model.Spencer, NY, Yan Z., Cong L., Zhang Y., Engelhardt JF, and Stanton RC Analytical biochemistry, 2015/11/11, (2015) Read More / View Supplemental Materials
Abstract
An integrated map of structural variation in 2,504 human genomes.Sudmant, PH, Rausch T., Gardner EJ, Handsaker RE, Abyzov A., Huddleston J., Zhang Y., Ye K., Jun G., Hsi-Yang Fritz M., Konkel MK, Malhotra A., Stütz AM, Shi X., Paolo Casale F., Chen J., Hormozdiari F., Dayama G., Chen K., Malig M., et al. Nature, 2015/10/01, Volume 526, Issue 7571, p.75-81, (2015) Read More / View Supplemental Materials
Abstract
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.Kato, N., Loh M., Takeuchi F., Verweij N., Wang X., Zhang W., Kelly TN, Saleheen D., Lehne B., Leach IM, Drong AW, Abbott J., Wahl S., Tan ST, Scott WR, Campanella G., Chadeau-Hyam M., Afzal U., Ahluwalia TS, Bonder MJ, et al. Nature genetics, 2015/09/21, (2015) Read More / View Supplemental Materials
Abstract
PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells.Das, PP, Hendrix DA, Apostolou E., Buchner AH, Canver MC, Beyaz S., Ljuboja D., Kuintzle R., Kim W., Karnik R., Shao Z., Xie H., Xu J., De Los Angeles A., Zhang Y., Choe J., Jun DL, Shen X., Gregory RI, Daley GQ, et al. Cell reports, 2015/08/19, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.Hayes, MG, Urbanek M., Ehrmann DA, Armstrong LL, Lee JY, Sisk R., Karaderi T., Barber TM, McCarthy MI, Franks S., Lindgren CM, Welt CK, Diamanti-Kandarakis E., Panidis D., Goodarzi MO, Azziz R., Zhang Y., James RG, Olivier M., Kissebah AH, et al. Nature communications, 2015/08/18, Volume 6, p.7502, (2015) Read More / View Supplemental Materials
Abstract
Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6.Park, E., Kim N., Ficarro SB, Zhang Y., Lee BI, Cho A., Kim K., Park AK, Park WY, Murray B., Meyerson M., Beroukhim R., Marto JA, Cho J., and Eck MJ Nature structural & molecular biology, 2015/08/17, (2015) Read More / View Supplemental Materials
Abstract
Light-weight reference-based compression of FASTQ data.Zhang, Y., Li L., Yang Y., Yang X., He S., and Zhu Z. BMC bioinformatics, 2015/06/09, Volume 16, Issue 1, p.188, (2015) Read More / View Supplemental Materials
Abstract
Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation.Biagioli, M., Ferrari F., Mendenhall EM, Zhang Y., Erdin S., Vijayvargia R., Vallabh SM, Solomos N., Manavalan P., Ragavendran A., Ozsolak F., Lee JM, Talkowski ME, Gusella JF, Macdonald ME, Park PJ, and Seong IS Human molecular genetics, 2015/01/08, (2015) Read More / View Supplemental Materials
Abstract
A New Imaging Platform for Visualizing Biological Effects of Non-Invasive Radiofrequency Electric-Field Cancer Hyperthermia.Corr, SJ, Shamsudeen S., Vergara LA, Cho J., Ware MJ, Keshishian V., Yokoi K., Savage DJ, Meraz IM, Kaluarachchi W., Cisneros BT, Raoof M., Nguyen DT, Zhang Y., Wilson LJ, Summers H., Rees P., Curley SA, and Serda RE PloS one, 2015/01/01, Volume 10, Issue 8, p.e0136382, (2015) Read More / View Supplemental Materials
Abstract
2014
DNA methylation signatures link prenatal famine exposure to growth and metabolism.Tobi, EW, Goeman JJ, Monajemi R., Gu H., Putter H., Zhang Y., Slieker RC, Stok AP, Thijssen PE, Müller F., van Zwet EW, Bock C., Meissner A., Lumey LH, Eline Slagboom P., and Heijmans BT Nature communications, 2014/11/26, Volume 5, p.5592, (2014) Read More / View Supplemental Materials
Abstract
Long-term persistence and development of induced pancreatic beta cells generated by lineage conversion of acinar cells.Li, W., Cavelti-Weder C., Zhang Y., Clement K., Donovan S., Gonzalez G., Zhu J., Stemann M., Xu K., Hashimoto T., Yamada T., Nakanishi M., Zhang Y., Zeng S., Gifford D., Meissner A., Weir G., and Zhou Q. Nature biotechnology, 2014/11/17, (2014) Read More / View Supplemental Materials
Abstract
Development of covalent inhibitors that can overcome resistance to first-generation FGFR kinase inhibitors.Tan, L., Wang J., Tanizaki J., Huang Z., Aref AR, Rusan M., Zhu SJ, Zhang Y., Ercan D., Liao RG, Capelletti M., Zhou W., Hur W., Kim N., Sim T., Gaudet S., Barbie DA, Yeh JR, Yun CH, Hammerman PS, et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/10/27, (2014) Read More / View Supplemental Materials
Abstract
CompMap: a reference-based compression program to speed up read mapping to related reference sequences.Zhu, Z., Li L., Zhang Y., Yang Y., and Yang X. Bioinformatics (Oxford, England), 2014/10/04, (2014) Read More / View Supplemental Materials
Abstract
Glycogen synthase kinase-3β inhibition ameliorates cardiac parasympathetic dysfunction in type 1 diabetic akita mice.Zhang, Y., Welzig CM, Picard KL, Du C., Wang B., Pan JQ, Kyriakis JM, Aronovitz MJ, Claycomb WC, Blanton RM, Park HJ, and Galper JB Diabetes, 2014/06/01, Volume 63, Issue 6, p.2097-113, (2014) Read More / View Supplemental Materials
Abstract
Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins.Kennedy, JJ, Abbatiello SE, Kim K., Yan P., Whiteaker JR, Lin C., Kim JS, Zhang Y., Wang X., Ivey RG, Zhao L., Min H., Lee Y., Yu MH, Yang EG, Lee C., Wang P., Rodriguez H., Kim Y., Carr SA, et al. Nature methods, 2014/02/01, Volume 11, Issue 2, p.149-55, (2014) Read More / View Supplemental Materials
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Standardized metadata for human pathogen/vector genomic sequences.Dugan, VG, Emrich SJ, Giraldo-Calderón GI, Harb OS, Newman RM, Pickett BE, Schriml LM, Stockwell TB, Stoeckert CJ Jr, Sullivan DE, Singh I., Ward DV, Yao A., Zheng J., Barrett T., Birren B., Brinkac L., Bruno VM, Caler E., Chapman S., et al. PloS one, 2014/01/01, Volume 9, Issue 6, p.e99979, (2014) Read More / View Supplemental Materials
Abstract
2013
High-throughput genetic screen for synaptogenic factors: identification of LRP6 as critical for excitatory synapse development.Sharma, K., Choi SY, Zhang Y., Nieland TJ, Long S., Li M., and Huganir RL Cell reports, 2013/12/12, Volume 5, Issue 5, p.1330-41, (2013) Read More / View Supplemental Materials
Abstract
Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity.Ran, FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S., Trevino AE, Scott DA, Inoue A., Matoba S., Zhang Y., and Zhang F. Cell, 2013/09/12, Volume 154, Issue 6, p.1380-9, (2013) Read More / View Supplemental Materials
Abstract
2012
Comprehensive genomic characterization of squamous cell lung cancers.The Cancer Genome Atlas Research, Network, institution.)(Participants are arranged by area of contribution and then by, Genome sequencing centres: Broad Institute, Hammerman PS, Lawrence MS, Voet D., Jing R., Cibulskis K., Sivachenko A., Stojanov P., McKenna A., Lander E. S., Gabriel S., Getz G., Sougnez C., Imielinski M., Helman E., Hernandez B., Pho NH, Meyerson M., et al. Nature, 2012/09/09, (2012) Read More / View Supplemental Materials
Abstract
Wisdom of crowds for robust gene network inference.Marbach, D., Costello JC, Küffner R., Vega NM, Prill RJ, Camacho DM, Allison KR, The DREAM5 Consortium, Aderhold A., Allison KR, Bonneau R., Camacho DM, Chen Y., Collins JJ, Cordero F., Costello JC, Crane M., Dondelinger F., Drton M., Esposito R., et al. Nature methods, 2012/07/15, (2012) Read More / View Supplemental Materials
Abstract
2011
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types.Ziller, MJ, Müller F., Liao J., Zhang Y., Gu H., Bock C., Boyle P., Epstein CB, Bernstein BE, Lengauer T., Gnirke A., and Meissner A. PLoS genetics, 2011/12/01, Volume 7, Issue 12, p.e1002389, (2011) Read More / View Supplemental Materials
Abstract
STK33 kinase activity is nonessential in KRAS-dependent cancer cells.Babij, C., Zhang Y., Kurzeja RJ, Munzli A., Shehabeldin A., Fernando M., Quon K., Kassner PD, Ruefli-Brasse AA, Watson VJ, Fajardo F., Jackson A., Zondlo J., Sun Y., Ellison AR, Plewa CA, San MT, Robinson J., McCarter J., Schwandner R., et al. Cancer research, 2011/09/01, Volume 71, Issue 17, p.5818-26, (2011) Read More / View Supplemental Materials
Abstract
Mapping copy number variation by population-scale genome sequencing.Mills, RE, Walter K., Stewart C., Handsaker RE, Chen K., Alkan C., Abyzov A., Yoon SC, Ye K., Cheetham RK, Chinwalla A., Conrad DF, Fu Y., Grubert F., Hajirasouliha I., Hormozdiari F., Iakoucheva LM, Iqbal Z., Kang S., Kidd JM, et al. Nature, 2011/02/03, Volume 470, Issue 7332, p.59-65, (2011) Read More / View Supplemental Materials
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2008
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations.Li, Z., Lu J., Sun M., Mi S., Zhang H., Luo RT, Chen P., Wang Y., Yan M., Qian Z., Neilly MB, Jin J., Zhang Y., Bohlander SK, Zhang DE, Larson RA, Le Beau MM, Thirman MJ, Golub T. R., Rowley JD, et al. Proceedings of the National Academy of Sciences of the United States of America, 2008/10/07, Volume 105, Issue 40, p.15535-40, (2008) Read More / View Supplemental Materials
Abstract
2007
MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia.Mi, S., Lu J., Sun M., Li Z., Zhang H., Neilly MB, Wang Y., Qian Z., Jin J., Zhang Y., Bohlander SK, Le Beau MM, Larson RA, Golub T. R., Rowley JD, and Chen J. Proceedings of the National Academy of Sciences of the United States of America, 2007/12/11, Volume 104, Issue 50, p.19971-6, (2007) Read More / View Supplemental Materials
Abstract
Evolution of genes and genomes on the Drosophila phylogeny.Drosophila 12 Genomes, Consortium, Clark AG, Eisen MB, Smith DR, Bergman CM, Oliver B., Markow TA, Kaufman TC, Kellis M., Gelbart W., Iyer VN, Pollard DA, Sackton TB, Larracuente AM, Singh ND, Abad JP, Abt DN, Adryan B., Aguade M., Akashi H., et al. Nature, 2007/11/08, Volume 450, Issue 7167, p.203-18, (2007) Read More / View Supplemental Materials
Abstract
  • Showing 1-30 of 30 Results