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Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.Tang, Y., Gholamin S., Schubert S., Willardson MI, Lee A., Bandopadhayay P., Bergthold G., Masoud S., Nguyen B., Vue N., Balansay B., Yu F., Oh S., Woo P., Chen S., Ponnuswami A., Monje M., Atwood SX, Whitson RJ, Mitra S., et al. Nature medicine, 2014/07/01, Volume 20, Issue 7, p.732-740, (2014) Read More / View Supplemental Materials
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.Kalaitzidis, D., Sykes SM, Wang Z., Punt N., Tang Y., Ragu C., Sinha AU, Lane SW, Souza AL, Clish CB, Anastasiou D., Gilliland DG, Scadden DT, Guertin DA, and Armstrong SA Cell stem cell, 2012/09/07, Volume 11, Issue 3, p.429-39, (2012) Read More / View Supplemental Materials
Image-based genome-wide siRNA screen identifies selective autophagy factors.Orvedahl, A., Sumpter R Jr, Xiao G., Ng A., Zou Z., Tang Y., Narimatsu M., Gilpin C., Sun Q., Roth M., Forst CV, Wrana JL, Zhang YE, Luby-Phelps K., Xavier RJ, Xie Y., and Levine B. Nature, 2011/12/01, Volume 480, Issue 7375, p.113-7, (2011) Read More / View Supplemental Materials
Somatic mutations affect key pathways in lung adenocarcinoma.Ding, L., Getz G., Wheeler DA, Mardis ER, McLellan MD, Cibulskis K., Sougnez C., Greulich H., Muzny DM, Morgan MB, Fulton L., Fulton RS, Zhang Q., Wendl MC, Lawrence MS, Larson DE, Chen K., Dooling DJ, Sabo A., Hawes AC, et al. Nature, 2008/10/23, Volume 455, Issue 7216, p.1069-75, (2008) Read More / View Supplemental Materials
Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor.Ng, PY, Tang Y., Knosp WM, Stadler HS, and Shaw JT Angewandte Chemie (International ed. in English), 2007/06/14, Volume 46, Issue 28, p.5352-5, (2007) Read More / View Supplemental Materials
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