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2015
The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.Herman, JD, Pepper LR, Cortese JF, Estiu G., Galinsky K., Zuzarte-Luis V., Derbyshire ER, Ribacke U., Lukens AK, Santos SA, Patel V., Clish CB, Sullivan WJ Jr, Zhou H., Bopp SE, Schimmel P., Lindquist S., Clardy J., Mota MM, Keller TL, et al. Science translational medicine, 2015/05/20, Volume 7, Issue 288, p.288ra77, (2015) Read More / View Supplemental Materials
Abstract
2009
Synthesis and histone deacetylase inhibitory activity of largazole analogs: alteration of the zinc-binding domain and macrocyclic scaffold.Bowers, AA, West N., Newkirk TL, Troutman-Youngman AE, Schreiber SL, Wiest O., Bradner JE, and Williams RM Organic letters, 2009/03/19, Volume 11, Issue 6, p.1301-4, (2009) Read More / View Supplemental Materials
Abstract
Synthesis and conformation-activity relationships of the peptide isosteres of FK228 and largazole.Bowers, AA, Greshock TJ, West N., Estiu G., Schreiber SL, Wiest O., Williams RM, and Bradner JE Journal of the American Chemical Society, 2009/03/04, Volume 131, Issue 8, p.2900-5, (2009) Read More / View Supplemental Materials
Abstract
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