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2008
Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiationHahn, Cynthia K., Ross Kenneth N., Warrington Ian M., Mazitschek Ralph, Kanegai Cindy M., Wright Renee D., Kung Andrew L., Golub Todd R., and Stegmaier Kimberly Proceedings of the National Academy of Sciences of the United States of America, 2008/07/15/, Volume 105, Issue 28, p.9751 - 6, (2008) Read More / View Supplemental Materials
Abstract
MicroRNA-mediated control of cell fate in megakaryocyte-erythrocyte progenitorsLu, Jun, Guo Shangqin, Ebert Benjamin L., Zhang Hao, Peng Xiao, Bosco Jocelyn, Pretz Jennifer, Schlanger Rita, Wang Judy Y., Mak Raymond H., Dombkowski David M., Preffer Frederic I., Scadden David T., and Golub Todd R. Developmental Cell, 2008/06//, Volume 14, Issue 6, p.843 - 53, (2008) Read More / View Supplemental Materials
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An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeEbert, Benjamin L., Galili Naomi, Tamayo Pablo, Bosco Jocelyn, Mak Raymond, Pretz Jennifer, Tanguturi Shyam, Ladd-Acosta Christine, Stone Richard, Golub Todd R., and Raza Azra PLoS Medicine, 2008/02//, Volume 5, Issue 2, p.e35 - e35, (2008) Read More / View Supplemental Materials
Abstract
An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeEbert, Benjamin L., Galili Naomi, Tamayo Pablo, Bosco Jocelyn, Mak Raymond, Pretz Jennifer, Tanguturi Shyam, Ladd-Acosta Christine, Stone Richard, Golub Todd R., and Raza Azra PLoS Medicine, 2008/02//, Volume 5, Issue 2, p.e35 - e35, (2008) Read More / View Supplemental Materials
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Identification of RPS14 as a 5q- syndrome gene by RNA interference screenEbert, Benjamin L., Pretz Jennifer, Bosco Jocelyn, Chang Cindy Y., Tamayo Pablo, Galili Naomi, Raza Azra, Root David E., Attar Eyal, Ellis Steven R., and Golub Todd R. Nature, 2008/01/17/, Volume 451, Issue 7176, p.335 - 9, (2008) Read More / View Supplemental Materials
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2007
Impaired microRNA processing enhances cellular transformation and tumorigenesisKumar, Madhu S., Lu Jun, Mercer Kim L., Golub Todd R., and Jacks Tyler Nature Genetics, 2007/05//, Volume 39, Issue 5, p.673 - 7, (2007) Read More / View Supplemental Materials
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Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcomaStegmaier, Kimberly, Wong Jenny S., Ross Kenneth N., Chow Kwan T., Peck David, Wright Renee D., Lessnick Stephen L., Kung Andrew L., and Golub Todd R. PLoS Medicine, 2007/04//, Volume 4, Issue 4, p.e122 - e122, (2007) Read More / View Supplemental Materials
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Subclass mapping: identifying common subtypes in independent disease data setsHoshida, Yujin, Brunet Jean-Philippe, Tamayo Pablo, Golub Todd R., and Mesirov Jill P. PLoS ONE, 2007///, Volume 2, Issue 11, p.e1195 - e1195, (2007) Read More / View Supplemental Materials
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2006
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulatorsHieronymus, Haley, Lamb Justin, Ross Kenneth N., Peng Xiao P., Clement Cristina, Rodina Anna, Nieto Maria, Du Jinyan, Stegmaier Kimberly, Raj Srilakshmi M., Maloney Katherine N., Clardy Jon, Hahn William C., Chiosis Gabriela, and Golub Todd R. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.321 - 30, (2006) Read More / View Supplemental Materials
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Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistanceWei, Guo, Twomey David, Lamb Justin, Schlis Krysta, Agarwal Jyoti, Stam Ronald W., Opferman Joseph T., Sallan Stephen E., den Boer Monique L., Pieters Rob, Golub Todd R., and Armstrong Scott A. Cancer Cell, 2006/10//, Volume 10, Issue 4, p.331 - 42, (2006) Read More / View Supplemental Materials
Abstract
Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9Krivtsov, Andrei V., Twomey David, Feng Zhaohui, Stubbs Matthew C., Wang Yingzi, Faber Joerg, Levine Jason E., Wang Jing, Hahn William C., Gilliland Gary D., Golub Todd R., and Armstrong Scott A. Nature, 2006/08/17/, Volume 442, Issue 7104, p.818 - 22, (2006) Read More / View Supplemental Materials
Abstract
Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcomaSmith, Richard, Owen Leah A., Trem Deborah J., Wong Jenny S., Whangbo Jennifer S., Golub Todd R., and Lessnick Stephen L. Cancer Cell, 2006/05//, Volume 9, Issue 5, p.405 - 16, (2006) Read More / View Supplemental Materials
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2005
Epstein-Barr-virus-encoded LMP2A induces primary epithelial cell migration and invasion: possible role in nasopharyngeal carcinoma metastasisPegtel, Dirk M., Subramanian Aravind, Sheen Tzung-Shiahn, Tsai Ching-Hwa, Golub Todd R., and Thorley-Lawson David A. Journal of Virology, 2005/12//, Volume 79, Issue 24, p.15430 - 42, (2005) Read More / View Supplemental Materials
Abstract
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesSubramanian, Aravind, Tamayo Pablo, Mootha Vamsi K., Mukherjee Sayan, Ebert Benjamin L., Gillette Michael A., Paulovich Amanda, Pomeroy Scott L., Golub Todd R., Lander Eric S., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2005/10/25/, Volume 102, Issue 43, p.15545 - 50, (2005) Read More / View Supplemental Materials
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Gefitinib induces myeloid differentiation of acute myeloid leukemiaStegmaier, Kimberly, Corsello Steven M., Ross Kenneth N., Wong Jenny S., Deangelo Daniel J., and Golub Todd R. Blood, 2005/10/15/, Volume 106, Issue 8, p.2841 - 8, (2005) Read More / View Supplemental Materials
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NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypesFeuerhake, Friedrich, Kutok Jeffery L., Monti Stefano, Chen Wen, LaCasce Ann S., Cattoretti Giorgio, Kurtin Paul, Pinkus Geraldine S., de Leval Laurence, Harris Nancy L., Savage Kerry J., Neuberg Donna, Habermann Thomas M., Dalla-Favera Riccardo, Golub Todd R., and A Blood, 2005/08/15/, Volume 106, Issue 4, p.1392 - 9, (2005) Read More / View Supplemental Materials
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Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanomaGarraway, Levi A., Widlund Hans R., Rubin Mark A., Getz Gad, Berger Aaron J., Ramaswamy Sridhar, Beroukhim Rameen, Milner Danny A., Granter Scott R., Du Jinyan, Lee Charles, Wagner Stephan N., Li Cheng, Golub Todd R., Rimm David L., Meyerson Matthew L., and Fisher David Nature, 2005/07/07/, Volume 436, Issue 7047, p.117 - 22, (2005) Read More / View Supplemental Materials
Abstract
An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarrayEbert, Benjamin L., Lee Michele M., Pretz Jennifer L., Subramanian Aravind, Mak Raymond, Golub Todd R., and Sieff Colin A. Blood, 2005/06/15/, Volume 105, Issue 12, p.4620 - 6, (2005) Read More / View Supplemental Materials
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MicroRNA expression profiles classify human cancersLu, Jun, Getz Gad, Miska Eric A., Alvarez-Saavedra Ezequiel, Lamb Justin, Peck David, Sweet-Cordero Alejandro, Ebert Benjamin L., Mak Raymond H., Ferrando Adolfo A., Downing James R., Jacks Tyler, Horvitz Robert H., and Golub Todd R. Nature, 2005/06/09/, Volume 435, Issue 7043, p.834 - 8, (2005) Read More / View Supplemental Materials
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Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammalsXie, Xiaohui, Lu Jun, Kulbokas E. J., Golub Todd R., Mootha Vamsi, Lindblad-Toh Kerstin, Lander Eric S., and Kellis Manolis Nature, 2005/03/17/, Volume 434, Issue 7031, p.338 - 45, (2005) Read More / View Supplemental Materials
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An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysisSweet-Cordero, Alejandro, Mukherjee Sayan, Subramanian Aravind, You Han, Roix Jeffrey J., Ladd-Acosta Christine, Mesirov Jill, Golub Todd R., and Jacks Tyler Nature Genetics, 2005/01//, Volume 37, Issue 1, p.48 - 55, (2005) Read More / View Supplemental Materials
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2004
Identification of AML1-ETO Modulators with Chemical GenomicsCorsello, Steven M., Roti Giovanni, Ross Kenneth N., Chow Kwan T., Golub Todd R., and Stegmaier Kimberly, unknown, (2004) Read More / View Supplemental Materials
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Genomic approaches to hematologic malignanciesEbert, Benjamin L., and Golub Todd R. Blood, 2004/08/15/, Volume 104, Issue 4, p.923 - 32, (2004) Read More / View Supplemental Materials
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Metagenes and molecular pattern discovery using matrix factorizationBrunet, Jean-Philippe, Tamayo Pablo, Golub Todd R., and Mesirov Jill P. Proceedings of the National Academy of Sciences of the United States of America, 2004/03/23/, Volume 101, Issue 12, p.4164 - 9, (2004) Read More / View Supplemental Materials
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Gene expression-based high-throughput screening(GE-HTS) and application to leukemia differentiationStegmaier, Kimberly, Ross Kenneth N., Colavito Sierra A., O'Malley Shawn, Stockwell Brent R., and Golub Todd R. Nature Genetics, 2004/03//, Volume 36, Issue 3, p.257 - 63, (2004) Read More / View Supplemental Materials
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2003
MLL-rearranged leukemias: insights from gene expression profilingArmstrong, Scott A., Golub Todd R., and Korsmeyer Stanley J. Seminars in Hematology, 2003/10//, Volume 40, Issue 4, p.268 - 73, (2003) Read More / View Supplemental Materials
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A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancerLamb, Justin, Ramaswamy Sridhar, Ford Heide L., Contreras Bernardo, Martinez Robert V., Kittrell Frances S., Zahnow Cynthia A., Patterson Nick, Golub Todd R., and Ewen Mark E. Cell, 2003/08/08/, Volume 114, Issue 3, p.323 - 34, (2003) Read More / View Supplemental Materials
Abstract
Gene expression-based classification of malignant gliomas correlates better with survival than histological classificationNutt, Catherine L., Mani D. R., Betensky Rebecca A., Tamayo Pablo, Cairncross Gregory J., Ladd Christine, Pohl Ute, Hartmann Christian, McLaughlin Margaret E., Batchelor Tracy T., Black Peter M., von Deimling Andreas, Pomeroy Scott L., Golub Todd R., and Louis David N. Cancer Research, 2003/04/01/, Volume 63, Issue 7, p.1602 - 7, (2003) Read More / View Supplemental Materials
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Gene expression-based classification of malignant gliomas correlates better with survival than histological classificationNutt, Catherine L., Mani D. R., Betensky Rebecca A., Tamayo Pablo, Cairncross Gregory J., Ladd Christine, Pohl Ute, Hartmann Christian, McLaughlin Margaret E., Batchelor Tracy T., Black Peter M., von Deimling Andreas, Pomeroy Scott L., Golub Todd R., and Louis David N. Cancer Research, 2003/04/01/, Volume 63, Issue 7, p.1602 - 7, (2003) Read More / View Supplemental Materials
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A molecular signature of metastasis in primary solid tumorsRamaswamy, Sridhar, Ross Ken N., Lander Eric S., and Golub Todd R. Nature Genetics, 2003/01//, Volume 33, Issue 1, p.49 - 54, (2003) Read More / View Supplemental Materials
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Estimating dataset size requirements for classifying DNA microarray dataMukherjee, Sayan, Tamayo Pablo, Rogers Simon, Rifkin Ryan, Engle Anna, Campbell Colin, Golub Todd R., and Mesirov Jill P. Journal of Computational Biology: A Journal of Computational Molecular Cell Biology, 2003///, Volume 10, Issue 2, p.119 - 42, (2003) Read More / View Supplemental Materials
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2002
The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblastsLessnick, Stephen L., Dacwag Caroline S., and Golub Todd R. Cancer Cell, 2002/05//, Volume 1, Issue 4, p.393 - 401, (2002) Read More / View Supplemental Materials
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DNA microarrays in clinical oncologyRamaswamy, Sridhar, and Golub Todd R. Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 2002/04/01/, Volume 20, Issue 7, p.1932 - 41, (2002) Read More / View Supplemental Materials
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Gene expression correlates of clinical prostate cancer behaviorSingh, Dinesh, Febbo Phillip G., Ross Kenneth, Jackson Donald G., Manola Judith, Ladd Christine, Tamayo Pablo, Renshaw Andrew A., D'Amico Anthony V., Richie Jerome P., Lander Eric S., Loda Massimo, Kantoff Philip W., Golub Todd R., and Sellers William R. Cancer Cell, 2002/03//, Volume 1, Issue 2, p.203 - 9, (2002) Read More / View Supplemental Materials
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Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemiaFerrando, Adolfo A., Neuberg Donna S., Staunton Jane, Loh Mignon L., Huard Christine, Raimondi Susana C., Behm Fred G., Pui Ching Hon, Downing James R., Gilliland Gary D., Lander Eric S., Golub Todd R., and Look Thomas A. Cancer Cell, 2002/02//, Volume 1, Issue 1, p.75 - 87, (2002) Read More / View Supplemental Materials
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MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemiaArmstrong, Scott A., Staunton Jane E., Silverman Lewis B., Pieters Rob, den Boer Monique L., Minden Mark D., Sallan Stephen E., Lander Eric S., Golub Todd R., and Korsmeyer Stanley J. Nature Genetics, 2002/01//, Volume 30, Issue 1, p.41 - 7, (2002) Read More / View Supplemental Materials
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A strategy for oligonucleotide microarray probe reductionAntipova, Alena A., Tamayo Pablo, and Golub Todd R. Genome Biology, 2002///, Volume 3, Issue 12, p.RESEARCH0073 - RESEARCH0073, (2002) Read More / View Supplemental Materials
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  • Showing 1-37 of 37 Results