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2016
52 Genetic Loci Influencing Myocardial Mass.van der Harst, P., van Setten J., Verweij N., Vogler G., Franke L., Maurano MT, Wang X., Mateo Leach I., Eijgelsheim M., Sotoodehnia N., Hayward C., Sorice R., Meirelles O., Lyytikäinen LP, Polašek O., Tanaka T., Arking DE, Ulivi S., Trompet S., Müller-Nurasyid M., et al. Journal of the American College of Cardiology, 2016/09/27, Volume 68, Issue 13, p.1435-48, (2016) Read More / View Supplemental Materials
Abstract
The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals.Ehret, GB, Ferreira T., Chasman DI, Jackson AU, Schmidt EM, Johnson T., Thorleifsson G., Luan J., Donnelly LA, Kanoni S., Petersen AK, Pihur V., Strawbridge RJ, Shungin D., Hughes MF, Meirelles O., Kaakinen M., Bouatia-Naji N., Kristiansson K., Shah S., et al. Nature genetics, 2016/09/12, (2016) Read More / View Supplemental Materials
Abstract
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.Surendran, P., Drenos F., Young R., Warren H., Cook JP, Manning AK, Grarup N., Sim X., Barnes DR, Witkowska K., Staley JR, Tragante V., Tukiainen T., Yaghootkar H., Masca N., Freitag DF, Ferreira T., Giannakopoulou O., Tinker A., Harakalova M., et al. Nature genetics, 2016/09/12, (2016) Read More / View Supplemental Materials
Abstract
A Whole-Blood Transcriptome Meta-Analysis Identifies Gene Expression Signatures of Cigarette Smoking.Huan, T., Joehanes R., Schurmann C., Schramm K., Pilling LC, Peters MJ, Mägi R., DeMeo D., O'Connor GT, Ferrucci L., Teumer A., Homuth G., Biffar R., Völker U., Herder C., Waldenberger M., Peters A., Zeilinger S., Metspalu A., Hofman A., et al. Human molecular genetics, 2016/08/29, (2016) Read More / View Supplemental Materials
Abstract
Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.Polfus, LM, Khajuria RK, Schick UM, Pankratz N., Pazoki R., Brody JA, Chen MH, Auer PL, Floyd JS, Huang J., Lange L., van Rooij FJ, Gibbs RA, Metcalf G., Muzny D., Veeraraghavan N., Walter K., Chen L., Yanek L., Becker LC, et al. American journal of human genetics, 2016/08/04, Volume 99, Issue 2, p.481-8, (2016) Read More / View Supplemental Materials
Abstract
The genetic architecture of type 2 diabetes.Fuchsberger, C., Flannick J., Teslovich TM, Mahajan A., Agarwala V., Gaulton KJ, Ma C., Fontanillas P., Moutsianas L., McCarthy DJ, Rivas MA, Perry JR, Sim X., Blackwell TW, Robertson NR, Rayner NW, Cingolani P., Locke AE, Tajes JF, Highland HM, et al. Nature, 2016/07/11, (2016) Read More / View Supplemental Materials
Abstract
Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.Chami, N., Chen MH, Slater AJ, Eicher JD, Evangelou E., Tajuddin SM, Love-Gregory L., Kacprowski T., Schick UM, Nomura A., Giri A., Lessard S., Brody JA, Schurmann C., Pankratz N., Yanek LR, Manichaikul A., Pazoki R., Mihailov E., Hill WD, et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases.Tajuddin, SM, Schick UM, Eicher JD, Chami N., Giri A., Brody JA, Hill WD, Kacprowski T., Li J., Lyytikäinen LP, Manichaikul A., Mihailov E., O'Donoghue ML, Pankratz N., Pazoki R., Polfus LM, Smith AV, Schurmann C., Vacchi-Suzzi C., Waterworth DM, et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.Eicher, JD, Chami N., Kacprowski T., Nomura A., Chen MH, Yanek LR, Tajuddin SM, Schick UM, Slater AJ, Pankratz N., Polfus L., Schurmann C., Giri A., Brody JA, Lange LA, Manichaikul A., Hill WD, Pazoki R., Elliot P., Evangelou E., et al. American journal of human genetics, 2016/06/21, (2016) Read More / View Supplemental Materials
Abstract
Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.Gormley, P., Anttila V., Winsvold BS, Palta P., Esko T., Pers TH, Farh KH, Cuenca-Leon E., Muona M., Furlotte NA, Kurth T., Ingason A., McMahon G., Ligthart L., Terwindt GM, Kallela M., Freilinger TM, Ran C., Gordon SG, Stam AH, et al. Nature genetics, 2016/06/20, (2016) Read More / View Supplemental Materials
Abstract
Genome-wide association study identifies 74 loci associated with educational attainment.Okbay, A., Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P., Chen GB, Emilsson V., Meddens SF, Oskarsson S., Pickrell JK, Thom K., Timshel P., de Vlaming R., Abdellaoui A., Ahluwalia TS, Bacelis J., Baumbach C., Bjornsdottir G., et al. Nature, 2016/05/11, Volume 533, Issue 7604, p.539-42, (2016) Read More / View Supplemental Materials
Abstract
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.Okbay, A., Baselmans BM, De Neve JE, Turley P., Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J., Gratten J., Lee JJ, Liu JZ, de Vlaming R., Ahluwalia TS, Buchwald J., Cavadino A., Frazier-Wood AC, Furlotte NA, Garfield V., et al. Nature genetics, 2016/04/18, (2016) Read More / View Supplemental Materials
Abstract
Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium.Stringer, S., Minică CC, Verweij KJ, Mbarek H., Bernard M., Derringer J., van Eijk KR, Isen JD, Loukola A., Maciejewski DF, Mihailov E., van der Most PJ, Sánchez-Mora C., Roos L., Sherva R., Walters R., Ware JJ, Abdellaoui A., Bigdeli TB, Branje SJ, et al. Translational psychiatry, 2016/03/29, Volume 6, p.e769, (2016) Read More / View Supplemental Materials
Abstract
Imprinted genes and imprinting control regions show predominant intermediate methylation in adult somatic tissues.Pervjakova, N., Kasela S., Morris AP, Kals M., Metspalu A., Lindgren CM, Salumets A., and Mägi R. Epigenomics, 2016/03/23, (2016) Read More / View Supplemental Materials
Abstract
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.Ellinghaus, D., Jostins L., Spain SL, Cortes A., Bethune J., Han B., Park YR, Raychaudhuri S., Pouget JG, Hübenthal M., Folseraas T., Wang Y., Esko T., Metspalu A., Westra HJ, Franke L., Pers TH, Weersma RK, Collij V., D'Amato M., et al. Nature genetics, 2016/03/14, (2016) Read More / View Supplemental Materials
Abstract
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.Pattaro, C., Teumer A., Gorski M., Chu AY, Li M., Mijatovic V., Garnaas M., Tin A., Sorice R., Li Y., Taliun D., Olden M., Foster M., Yang Q., Chen MH, Pers TH, Johnson AD, Ko YA, Fuchsberger C., Tayo B., et al. Nature communications, 2016/01/21, Volume 7, p.10023, (2016) Read More / View Supplemental Materials
Abstract
Ancient Haplotypes at the 15q24.2 Microdeletion Region Are Linked to Brain Expression of MAN2C1 and Children's Intelligence.Cáceres, A., Esko T., Pappa I., Gutiérrez A., Lopez-Espinosa MJ, Llop S., Bustamante M., Tiemeier H., Metspalu A., Joshi PK, Wilsonx JF, Reina-Castillón J., Shin J., Pausova Z., Paus T., Sunyer J., Pérez-Jurado LA, and González JR PloS one, 2016/01/01, Volume 11, Issue 6, p.e0157739, (2016) Read More / View Supplemental Materials
Abstract
2015
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.Gaulton, KJ, Ferreira T., Lee Y., Raimondo A., Mägi R., Reschen ME, Mahajan A., Locke A., William Rayner N., Robertson N., Scott RA, Prokopenko I., Scott LJ, Green T., Sparso T., Thuillier D., Yengo L., Grallert H., Wahl S., Frånberg M., et al. Nature genetics, 2015/11/09, (2015) Read More / View Supplemental Materials
Abstract
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.Day, FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N., Chasman DI, Stolk L., Finucane HK, Sulem P., Bulik-Sullivan B., Esko T., Johnson AD, Elks CE, Franceschini N., He C., Altmaier E., Brody JA, Franke LL, Huffman JE, Keller MF, et al. Nature genetics, 2015/11/01, Volume 47, Issue 11, p.1294-303, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide genetic homogeneity between sexes and populations for human height and body mass index.Yang, J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen AA, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., study LifeLines Cohort, Esko T., Milani L., Mägi R., Metspalu A., Hamsten A., Magnusson PK, Pedersen NL, Ingelsson E., and Visscher PM Human molecular genetics, 2015/10/22, (2015) Read More / View Supplemental Materials
Abstract
The transcriptional landscape of age in human peripheral blood.Peters, MJ, Joehanes R., Pilling LC, Schurmann C., Conneely KN, Powell J., Reinmaa E., Sutphin GL, Zhernakova A., Schramm K., Wilson YA, Kobes S., Tukiainen T., NABEC/UKBEC Consortium, Ramos YF, Göring HH, Fornage M., Liu Y., Gharib SA, Stranger BE, et al. Nature communications, 2015/10/22, Volume 6, p.8570, (2015) Read More / View Supplemental Materials
Abstract
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.Winkler, TW, Justice AE, Graff M., Barata L., Feitosa MF, Chu S., Czajkowski J., Esko T., Fall T., Kilpeläinen TO, Lu Y., Mägi R., Mihailov E., Pers TH, Rüeger S., Teumer A., Ehret GB, Ferreira T., Heard-Costa NL, Karjalainen J., et al. PLoS genetics, 2015/10/01, Volume 11, Issue 10, p.e1005378, (2015) Read More / View Supplemental Materials
Abstract
Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.Kato, N., Loh M., Takeuchi F., Verweij N., Wang X., Zhang W., Kelly TN, Saleheen D., Lehne B., Leach IM, Drong AW, Abbott J., Wahl S., Tan ST, Scott WR, Campanella G., Chadeau-Hyam M., Afzal U., Ahluwalia TS, Bonder MJ, et al. Nature genetics, 2015/09/21, (2015) Read More / View Supplemental Materials
Abstract
Population genetic differentiation of height and body mass index across Europe.Robinson, MR, Hemani G., Medina-Gomez C., Mezzavilla M., Esko T., Shakhbazov K., Powell JE, Vinkhuyzen A., Berndt SI, Gustafsson S., Justice AE, Kahali B., Locke AE, Pers TH, Vedantam S., Wood AR, van Rheenen W., Andreassen OA, Gasparini P., Metspalu A., et al. Nature genetics, 2015/09/14, (2015) Read More / View Supplemental Materials
Abstract
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index.Yang, J., Bakshi A., Zhu Z., Hemani G., Vinkhuyzen AA, Lee SH, Robinson MR, Perry JR, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., study LifeLines Cohort, Esko T., Milani L., Mägi R., Metspalu A., Hamsten A., Magnusson PK, Pedersen NL, Ingelsson E., et al. Nature genetics, 2015/08/31, (2015) Read More / View Supplemental Materials
Abstract
Rare coding variants and X-linked loci associated with age at menarche.Lunetta, KL, Day FR, Sulem P., Ruth KS, Tung JY, Hinds DA, Esko T., Elks CE, Altmaier E., He C., Huffman JE, Mihailov E., Porcu E., Robino A., Rose LM, Schick UM, Stolk L., Teumer A., Thompson DJ, Traglia M., et al. Nature communications, 2015/08/04, Volume 6, p.7756, (2015) Read More / View Supplemental Materials
Abstract
Directional dominance on stature and cognition in diverse human populations.Joshi, PK, Esko T., Mattsson H., Eklund N., Gandin I., Nutile T., Jackson AU, Schurmann C., Smith AV, Zhang W., Okada Y., Stančáková A., Faul JD, Zhao W., Bartz TM, Concas MP, Franceschini N., Enroth S., Vitart V., Trompet S., et al. Nature, 2015/07/01, (2015) Read More / View Supplemental Materials
Abstract
Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.Horikoshi, M., Mӓgi R., van de Bunt M., Surakka I., Sarin AP, Mahajan A., Marullo L., Thorleifsson G., Hӓgg S., Hottenga JJ, Ladenvall C., Ried JS, Winkler TW, Willems SM, Pervjakova N., Esko T., Beekman M., Nelson CP, Willenborg C., Wiltshire S., et al. PLoS genetics, 2015/07/01, Volume 11, Issue 7, p.e1005230, (2015) Read More / View Supplemental Materials
Abstract
Structural forms of the human amylase locus and their relationships to SNPs, haplotypes and obesity.Usher, CL, Handsaker RE, Esko T., Tuke MA, Weedon MN, Hastie AR, Cao H., Moon JE, Kashin S., Fuchsberger C., Metspalu A., Pato CN, Pato MT, McCarthy MI, Boehnke M., Altshuler DM, Frayling TM, Hirschhorn JN, and McCarroll SA Nature genetics, 2015/06/22, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.Draisma, HH, Pool R., Kobl M., Jansen R., Petersen AK, Vaarhorst AA, Yet I., Haller T., Demirkan A., Esko T., Zhu G., Böhringer S., Beekman M., van Klinken JB, Römisch-Margl W., Prehn C., Adamski J., de Craen AJ, van Leeuwen EM, Amin N., et al. Nature communications, 2015/06/12, Volume 6, p.7208, (2015) Read More / View Supplemental Materials
Abstract
The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects.Peyrot, WJ, Lee SH, Milaneschi Y., Abdellaoui A., Byrne EM, Esko T., de Geus EJ, Hemani G., Hottenga JJ, Kloiber S., Levinson DF, Lucae S., Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium(Corporate Collaborator), Martin NG, Medland SE, Metspalu A., Milani L., Noethen MM, Potash JB, Rietschel M., et al. Molecular psychiatry, 2015/06/01, Volume 20, Issue 6, p.735-43, (2015) Read More / View Supplemental Materials
Abstract
Adiposity as a cause of cardiovascular disease: a Mendelian randomization study.Hägg, S., Fall T., Ploner A., Mägi R., Fischer K., Draisma HH, Kals M., de Vries PS, Dehghan A., Willems SM, Sarin AP, Kristiansson K., Nuotio ML, Havulinna AS, de Bruijn RF, Ikram MA, Kuningas M., Stricker BH, Franco OH, Benyamin B., et al. International journal of epidemiology, 2015/05/27, (2015) Read More / View Supplemental Materials
Abstract
The impact of low-frequency and rare variants on lipid levels.Surakka, I., Horikoshi M., Mägi R., Sarin AP, Mahajan A., Lagou V., Marullo L., Ferreira T., Miraglio B., Timonen S., Kettunen J., Pirinen M., Karjalainen J., Thorleifsson G., Hägg S., Hottenga JJ, Isaacs A., Ladenvall C., Beekman M., Esko T., et al. Nature genetics, 2015/05/11, (2015) Read More / View Supplemental Materials
Abstract
Cell Specific eQTL Analysis without Sorting Cells.Westra, HJ, Arends D., Esko T., Peters MJ, Schurmann C., Schramm K., Kettunen J., Yaghootkar H., Fairfax BP, Andiappan AK, Li Y., Fu J., Karjalainen J., Platteel M., Visschedijk M., Weersma RK, Kasela S., Milani L., Tserel L., Peterson P., et al. PLoS genetics, 2015/05/01, Volume 11, Issue 5, p.e1005223, (2015) Read More / View Supplemental Materials
Abstract
A Meta-analysis of Gene Expression Signatures of Blood Pressure and Hypertension.Huan, T., Esko T., Peters MJ, Pilling LC, Schramm K., Schurmann C., Chen BH, Liu C., Joehanes R., Johnson AD, Yao C., Ying SX, Courchesne P., Milani L., Raghavachari N., Wang R., Liu P., Reinmaa E., Dehghan A., Hofman A., et al. PLoS genetics, 2015/03/01, Volume 11, Issue 3, p.e1005035, (2015) Read More / View Supplemental Materials
Abstract
Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors.Fall, T., Hägg S., Ploner A., Mägi R., Fischer K., Draisma HH, Sarin AP, Benyamin B., Ladenvall C., Åkerlund M., Kals M., Esko T., Nelson CP, Kaakinen M., Huikari V., Mangino M., Meirhaeghe A., Kristiansson K., Nuotio ML, Kobl M., et al. Diabetes, 2015/02/23, (2015) Read More / View Supplemental Materials
Abstract
Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
New genetic loci link adipose and insulin biology to body fat distribution.Shungin, D., Winkler TW, Croteau-Chonka DC, Ferreira T., Locke AE, Mägi R., Strawbridge RJ, Pers TH, Fischer K., Justice AE, Workalemahu T., Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C., Gustafsson S., Day FR, Esko T., et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.187-96, (2015) Read More / View Supplemental Materials
Abstract
Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits.Zhu, Z., Bakshi A., Vinkhuyzen AA, Hemani G., Lee SH, Nolte IM, van Vliet-Ostaptchouk JV, Snieder H., The LifeLines Cohort Study, Esko T., Milani L., Mägi R., Metspalu A., Hill WG, Weir BS, Goddard ME, Visscher PM, and Yang J. American journal of human genetics, 2015/02/11, (2015) Read More / View Supplemental Materials
Abstract
Haplotype phasing and inheritance of copy number variants in nuclear families.Palta, P., Kaplinski L., Nagirnaja L., Veidenberg A., Möls M., Nelis M., Esko T., Metspalu A., Laan M., and Remm M. PloS one, 2015/01/01, Volume 10, Issue 4, p.e0122713, (2015) Read More / View Supplemental Materials
Abstract
Modulation of genetic associations with serum urate levels by body-mass-index in humans.Huffman, JE, Albrecht E., Teumer A., Mangino M., Kapur K., Johnson T., Kutalik Z., Pirastu N., Pistis G., Lopez LM, Haller T., Salo P., Goel A., Li M., Tanaka T., Dehghan A., Ruggiero D., Malerba G., Smith AV, Nolte IM, et al. PloS one, 2015/01/01, Volume 10, Issue 3, p.e0119752, (2015) Read More / View Supplemental Materials
Abstract
Within-trait heterogeneity in age group differences in personality domains and facets: implications for the development and coherence of personality traits.Mõttus, R., Realo A., Allik J., Esko T., Metspalu A., and Johnson W. PloS one, 2015/01/01, Volume 10, Issue 3, p.e0119667, (2015) Read More / View Supplemental Materials
Abstract
2014
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.Benyamin, B., Esko T., Ried JS, Radhakrishnan A., Vermeulen SH, Traglia M., Gögele M., Anderson D., Broer L., Podmore C., Luan J., Kutalik Z., Sanna S., van der Meer P., Tanaka T., Wang F., Westra HJ, Franke L., Mihailov E., Milani L., et al. Nature communications, 2014/10/29, Volume 5, p.4926, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.The Coffee and Caffeine Genetics, Consortium, Cornelis MC, Byrne EM, Esko T., Nalls MA, Ganna A., Paynter N., Monda KL, Amin N., Fischer K., Renstrom F., Ngwa JS, Huikari V., Cavadino A., Nolte IM, Teumer A., Yu K., Marques-Vidal P., Rawal R., Manichaikul A., et al. Molecular psychiatry, 2014/10/07, (2014) Read More / View Supplemental Materials
Abstract
Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
Abstract
Hemani et al. reply.Hemani, G., Shakhbazov K., Westra HJ, Esko T., Henders AK, McRae AF, Yang J., Gibson G., Martin NG, Metspalu A., Franke L., Montgomery GW, Visscher PM, and Powell JE Nature, 2014/10/02, Volume 514, Issue 7520, p.E5-6, (2014) Read More / View Supplemental Materials
Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance.Ramos, YF, Metrustry S., Arden N., Bay-Jensen AC, Beekman M., de Craen AJ, Cupples LA, Esko T., Evangelou E., Felson DT, Hart DJ, Ioannidis JP, Karsdal M., Kloppenburg M., Lafeber F., Metspalu A., Panoutsopoulou K., Slagboom PE, Spector TD, van Spil EW, et al. Journal of medical genetics, 2014/07/23, (2014) Read More / View Supplemental Materials
Abstract
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.Perry, JR, Day F., Elks CE, Sulem P., Thompson DJ, Ferreira T., He C., Chasman DI, Esko T., Thorleifsson G., Albrecht E., Ang WQ, Corre T., Cousminer DL, Feenstra B., Franceschini N., Ganna A., Johnson AD, Kjellqvist S., Lunetta KL, et al. Nature, 2014/07/23, (2014) Read More / View Supplemental Materials
Abstract
Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population.Lim, ET, Würtz P., Havulinna AS, Palta P., Tukiainen T., Rehnström K., Esko T., Mägi R., Inouye M., Lappalainen T., Chan Y., Salem RM, Lek M., Flannick J., Sim X., Manning A., Ladenvall C., Bumpstead S., Hämäläinen E., Aalto K., et al. PLoS genetics, 2014/07/01, Volume 10, Issue 7, p.e1004494, (2014) Read More / View Supplemental Materials
Abstract
Novel Approach Identifies SNPs in SLC2A10 and KCNK9 with Evidence for Parent-of-Origin Effect on Body Mass Index.Hoggart, CJ, Venturini G., Mangino M., Gomez F., Ascari G., Zhao JH, Teumer A., Winkler TW, Tšernikova N., Luan J., Mihailov E., Ehret GB, Zhang W., Lamparter D., Esko T., Macé A., Rüeger S., Bochud PY, Barcella M., Dauvilliers Y., et al. PLoS genetics, 2014/07/01, Volume 10, Issue 7, p.e1004508, (2014) Read More / View Supplemental Materials
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Detection and replication of epistasis influencing transcription in humans.Hemani, G., Shakhbazov K., Westra HJ, Esko T., Henders AK, McRae AF, Yang J., Gibson G., Martin NG, Metspalu A., Franke L., Montgomery GW, Visscher PM, and Powell JE Nature, 2014/02/26, (2014) Read More / View Supplemental Materials
Abstract
Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu.Leitsalu, L., Haller T., Esko T., Tammesoo ML, Alavere H., Snieder H., Perola M., Ng PC, Mägi R., Milani L., Fischer K., and Metspalu A. International journal of epidemiology, 2014/02/11, (2014) Read More / View Supplemental Materials
Abstract
Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons.Fischer, K., Kettunen J., Würtz P., Haller T., Havulinna AS, Kangas AJ, Soininen P., Esko T., Tammesoo ML, Mägi R., Smit S., Palotie A., Ripatti S., Salomaa V., Ala-Korpela M., Perola M., and Metspalu A. PLoS medicine, 2014/02/01, Volume 11, Issue 2, p.e1001606, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
Abstract
Common variants associated with plasma triglycerides and risk for coronary artery disease.Do, R., Willer CJ, Schmidt EM, Sengupta S., Gao C., Peloso GM, Gustafsson S., Kanoni S., Ganna A., Chen J., Buchkovich ML, Mora S., Beckmann JS, Bragg-Gresham JL, Chang HY, Demirkan A., Den Hertog HM, Donnelly LA, Ehret GB, Esko T., et al. Nature genetics, 2013/11/01, Volume 45, Issue 11, p.1345-52, (2013) Read More / View Supplemental Materials
Abstract
2010
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.Speliotes, EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G., Jackson AU, Allen HL, Lindgren CM, Luan J., Mägi R., Randall JC, Vedantam S., Winkler TW, Qi L., Workalemahu T., Heid IM, Steinthorsdottir V., Stringham HM, Weedon MN, Wheeler E., et al. Nature genetics, 2010/11/01, Volume 42, Issue 11, p.937-48, (2010) Read More / View Supplemental Materials
Abstract
  • Showing 1-56 of 56 Results