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  • Showing 1-15 of 15 Results
2016
Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.Wakabayashi, A., Ulirsch JC, Ludwig LS, Fiorini C., Yasuda M., Choudhuri A., McDonel P., Zon LI, and Sankaran VG Proceedings of the National Academy of Sciences of the United States of America, 2016/04/04, (2016) Read More / View Supplemental Materials
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Regulation of the fetal hemoglobin silencing factor BCL11A.Basak, A., and Sankaran VG Annals of the New York Academy of Sciences, 2016/03/09, (2016) Read More / View Supplemental Materials
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Advances in understanding erythropoiesis: evolving perspectives.Nandakumar, SK, Ulirsch JC, and Sankaran VG British journal of haematology, 2016/02/05, (2016) Read More / View Supplemental Materials
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2015
Society for Pediatric Research 2015 Young Investigator Award: Genetics of human hematopoiesis-What patients can teach us about blood cell production.Wakabayashi, A., and Sankaran VG Pediatric research, 2015/11/17, (2015) Read More / View Supplemental Materials
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Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells.Giani, FC, Fiorini C., Wakabayashi A., Ludwig LS, Salem RM, Jobaliya CD, Regan SN, Ulirsch JC, Liang G., Steinberg-Shemer O., Guo MH, Esko T., Tong W., Brugnara C., Hirschhorn JN, Weiss MJ, Zon LI, Chou ST, French DL, Musunuru K., et al. Cell stem cell, 2015/10/20, (2015) Read More / View Supplemental Materials
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Anemia: progress in molecular mechanisms and therapies.Sankaran, VG, and Weiss MJ Nature medicine, 2015/03/05, Volume 21, Issue 3, p.221-230, (2015) Read More / View Supplemental Materials
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Genome-wide association study follow-up identifies cyclin A2 as a regulator of the transition through cytokinesis during terminal erythropoiesis.Ludwig, LS, Cho H., Wakabayashi A., Eng JC, Ulirsch JC, Fleming MD, Lodish HF, and Sankaran VG American journal of hematology, 2015/01/23, (2015) Read More / View Supplemental Materials
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2014
Altered chromatin occupancy of master regulators underlies evolutionary divergence in the transcriptional landscape of erythroid differentiation.Ulirsch, JC, Lacy JN, An X., Mohandas N., Mikkelsen TS, and Sankaran VG PLoS genetics, 2014/12/01, Volume 10, Issue 12, p.e1004890, (2014) Read More / View Supplemental Materials
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Altered translation of GATA1 in Diamond-Blackfan anemia.Ludwig, LS, Gazda HT, Eng JC, Eichhorn SW, Thiru P., Ghazvinian R., George TI, Gotlib JR, Beggs AH, Sieff CA, Lodish HF, Lander E. S., and Sankaran VG Nature medicine, 2014/06/22, (2014) Read More / View Supplemental Materials
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2013
Stimulating erythropoiesis in neonates.Sankaran, VG, and Agrawal PB American journal of hematology, 2013/08/20, (2013) Read More / View Supplemental Materials
Genome-wide association studies of hematologic phenotypes: a window into human hematopoiesis.Sankaran, VG, and Orkin SH Current opinion in genetics & development, 2013/03/07, (2013) Read More / View Supplemental Materials
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2012
Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number.Sankaran, VG, Ludwig LS, Sicinska E., Xu J., Bauer DE, Eng JC, Patterson HC, Metcalf RA, Natkunam Y., Orkin SH, Sicinski P., Lander E. S., and Lodish HF Genes & development, 2012/09/15, Volume 26, Issue 18, p.2075-87, (2012) Read More / View Supplemental Materials
Abstract
Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia.Sankaran, VG, Ghazvinian R., Do R., Thiru P., Vergilio JA, Beggs AH, Sieff CA, Orkin SH, Nathan DG, Lander E. S., and Gazda HT The Journal of clinical investigation, 2012/07/02, Volume 122, Issue 7, p.2439-43, (2012) Read More / View Supplemental Materials
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2011
MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13.Sankaran, VG, Menne TF, Šćepanović D., Vergilio JA, Ji P., Kim J., Thiru P., Orkin SH, Lander E. S., and Lodish HF Proceedings of the National Academy of Sciences of the United States of America, 2011/01/25, Volume 108, Issue 4, p.1519-24, (2011) Read More / View Supplemental Materials
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2008
DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.Lettre, G., Sankaran VG, Bezerra MA, Araújo AS, Uda M., Sanna S., Cao A., Schlessinger D., Costa FF, Hirschhorn JN, and Orkin SH Proceedings of the National Academy of Sciences of the United States of America, 2008/08/19, Volume 105, Issue 33, p.11869-74, (2008) Read More / View Supplemental Materials
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  • Showing 1-15 of 15 Results