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2015
Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.Schreiber, SL, Kotz JD, Li M., Aubé J., Austin CP, Reed JC, Rosen H., White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, De Souza A., Foley MA, Palmer M., Shamji AF, Wawer MJ, McManus O., Wu M., et al. Cell, 2015/06/04, Volume 161, Issue 6, p.1252-1265, (2015) Read More / View Supplemental Materials
Abstract
Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors.Chattopadhyay, S., Stewart AL, Mukherjee S., Huang C., Hartwell KA, Miller PG, Subramanian R., Carmody LC, Yusuf RZ, Sykes DB, Paulk J., Vetere A., Vallet S., Santo L., Cirstea DD, Hideshima T., Dančík V., Majireck MM, Hussain MM, Singh S., et al. Cell reports, 2015/02/04, (2015) Read More / View Supplemental Materials
Abstract
Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.Martins, MM, Zhou AY, Corella A., Horiuchi D., Yau C., Rakshandehroo T., Gordan JD, Levin RS, Johnson J., Jascur J., Shales M., Sorrentino A., Cheah J., Clemons PA, Shamji AF, Schreiber SL, Krogan NJ, Shokat KM, McCormick F., Goga A., et al. Cancer discovery, 2015/02/01, Volume 5, Issue 2, p.154-67, (2015) Read More / View Supplemental Materials
Abstract
High-throughput luminescent reporter of insulin secretion for discovering regulators of pancreatic Beta-cell function.Burns, SM, Vetere A., Walpita D., Dančík V., Khodier C., Perez J., Clemons PA, Wagner BK, and Altshuler D. Cell metabolism, 2015/01/06, Volume 21, Issue 1, p.126-37, (2015) Read More / View Supplemental Materials
Abstract
2014
Integrating phenotypic small-molecule profiling and human genetics: the next phase in drug discovery.Johannessen, CM, Clemons PA, and Wagner BK Trends in genetics : TIG, 2014/12/11, (2014) Read More / View Supplemental Materials
Abstract
BioAssay Research Database (BARD): chemical biology and probe-development enabled by structured metadata and result types.Howe, EA, De Souza A., Lahr DL, Chatwin S., Montgomery P., Alexander BR, Nguyen DT, Cruz Y., Stonich DA, Walzer G., Rose JT, Picard SC, Liu Z., Rose JN, Xiang X., Asiedu J., Durkin D., Levine J., Yang JJ, Schürer SC, et al. Nucleic acids research, 2014/12/04, (2014) Read More / View Supplemental Materials
Abstract
NAMPT is the cellular target of STF-31-like small-molecule probes.Adams, DJ, Ito D., Rees MG, Seashore-Ludlow B., Puyang X., Ramos AH, Cheah JH, Clemons PA, Warmuth M., Zhu P., Shamji AF, and Schreiber SL ACS chemical biology, 2014/10/17, Volume 9, Issue 10, p.2247-54, (2014) Read More / View Supplemental Materials
Abstract
Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality.Jerby-Arnon, L., Pfetzer N., Waldman YY, McGarry L., James D., Shanks E., Seashore-Ludlow B., Weinstock A., Geiger T., Clemons PA, Gottlieb E., and Ruppin E. Cell, 2014/08/28, Volume 158, Issue 5, p.1199-209, (2014) Read More / View Supplemental Materials
Abstract
Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling.Wawer, MJ, Li K., Gustafsdottir SM, Ljosa V., Bodycombe NE, Marton MA, Sokolnicki KL, Bray MA, Kemp MM, Winchester E., Taylor B., Grant GB, Hon CS, Duvall JR, Wilson JA, Bittker JA, Dančík V., Narayan R., Subramanian A., Winckler W., et al. Proceedings of the National Academy of Sciences of the United States of America, 2014/07/14, (2014) Read More / View Supplemental Materials
Abstract
Knowledge from Small-Molecule Screening and Profiling Data.Green, DV, and Clemons PA Journal of biomolecular screening, 2014/05/19, Volume 19, Issue 5, p.611-613, (2014) Read More / View Supplemental Materials
Automated Structure-Activity Relationship Mining: Connecting Chemical Structure to Biological Profiles.Wawer, MJ, Jaramillo DE, Dančik V., Fass DM, Haggarty SJ, Shamji AF, Wagner BK, Schreiber SL, and Clemons PA Journal of biomolecular screening, 2014/04/07, (2014) Read More / View Supplemental Materials
Abstract
Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses.Dancík, V., Carrel H., Bodycombe NE, Seiler KP, Fomina-Yadlin D., Kubicek ST, Hartwell K., Shamji AF, Wagner BK, and Clemons PA Journal of biomolecular screening, 2014/01/24, (2014) Read More / View Supplemental Materials
Abstract
An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines.De Souza, A., Bittker JA, Lahr DL, Brudz S., Chatwin S., Oprea TI, Waller A., Yang JJ, Southall N., Guha R., Schürer SC, Vempati UD, Southern MR, Dawson ES, Clemons PA, and Chung TD Journal of biomolecular screening, 2014/01/17, Volume 19, Issue 5, p.614-627, (2014) Read More / View Supplemental Materials
Abstract
Regulation of ferroptotic cancer cell death by GPX4.Yang, WS, Sriramaratnam R., Welsch ME, Shimada K., Skouta R., Viswanathan VS, Cheah JH, Clemons PA, Shamji AF, Clish CB, Brown LM, Girotti AW, Cornish VW, Schreiber SL, and Stockwell BR Cell, 2014/01/16, Volume 156, Issue 1-2, p.317-31, (2014) Read More / View Supplemental Materials
Abstract
Evolving BioAssay Ontology (BAO): modularization, integration and applications.Abeyruwan, S., Vempati UD, Küçük-McGinty H., Visser U., Koleti A., Mir A., Sakurai K., Chung C., Bittker JA, Clemons PA, Brudz S., Siripala A., Morales AJ, Romacker M., Twomey D., Bureeva S., Lemmon V., and Schürer SC Journal of biomedical semantics, 2014/01/01, Volume 5, Issue Suppl 1 Proceedings of the Bio-Ontologies Spec Interest G, p.S5, (2014) Read More / View Supplemental Materials
Abstract
Quantitative-proteomic comparison of alpha and Beta cells to uncover novel targets for lineage reprogramming.Choudhary, A., Hu He K., Mertins P., Udeshi ND, Dančík V., Fomina-Yadlin D., Kubicek S., Clemons PA, Schreiber SL, Carr SA, and Wagner BK PloS one, 2014/01/01, Volume 9, Issue 4, p.e95194, (2014) Read More / View Supplemental Materials
Abstract
2013
Multiplex cytological profiling assay to measure diverse cellular States.Gustafsdottir, SM, Ljosa V., Sokolnicki KL, Anthony Wilson J., Walpita D., Kemp MM, Petri Seiler K., Carrel HA, Golub T. R., Schreiber SL, Clemons PA, Carpenter AE, and Shamji AF PloS one, 2013/12/02, Volume 8, Issue 12, p.e80999, (2013) Read More / View Supplemental Materials
Abstract
Comparison of methods for image-based profiling of cellular morphological responses to small-molecule treatment.Ljosa, V., Caie PD, Ter Horst R., Sokolnicki KL, Jenkins EL, Daya S., Roberts ME, Jones TR, Singh S., Genovesio A., Clemons PA, Carragher NO, and Carpenter AE Journal of biomolecular screening, 2013/12/01, Volume 18, Issue 10, p.1321-9, (2013) Read More / View Supplemental Materials
Abstract
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.Hartwell, KA, Miller PG, Mukherjee S., Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M., Järås M., Puram R., Dancik V., Al-Shahrour F., Kindler T., Tothova Z., Chattopadhyay S., Hasaka T., Narayan R., Dai M., Huang C., Shterental S., et al. Nature chemical biology, 2013/12/01, Volume 9, Issue 12, p.840-8, (2013) Read More / View Supplemental Materials
Abstract
An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.Basu, A., Bodycombe NE, Cheah JH, Price EV, Liu K., Schaefer GI, Ebright RY, Stewart ML, Ito D., Wang S., Bracha AL, Liefeld T., Wawer M., Gilbert JC, Wilson AJ, Stransky N., Kryukov GV, Dancik V., Barretina J., Garraway LA, et al. Cell, 2013/08/29, Volume 154, Issue 5, p.1151-61, (2013) Read More / View Supplemental Materials
Abstract
Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway.Li, G., Diogo D., Wu D., Spoonamore J., Dancik V., Franke L., Kurreeman F., Rossin EJ, Duclos G., Hartland C., Zhou X., Li K., Liu J., De Jager PL, Siminovitch KA, Zhernakova A., Raychaudhuri S., Bowes J., Eyre S., Padyukov L., et al. PLoS genetics, 2013/05/01, Volume 9, Issue 5, p.e1003487, (2013) Read More / View Supplemental Materials
Abstract
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.Mulrooney, CA, Lahr DL, Quintin MJ, Youngsaye W., Moccia D., Asiedu JK, Mulligan EL, Akella LB, Marcaurelle LA, Montgomery P., Bittker JA, Clemons PA, Brudz S., Dandapani S., Duvall JR, Tolliday NJ, and De Souza A. Journal of computer-aided molecular design, 2013/04/13, (2013) Read More / View Supplemental Materials
Abstract
Target identification and mechanism of action in chemical biology and drug discovery.Schenone, M., Dančík V., Wagner BK, and Clemons PA Nature chemical biology, 2013/04/01, Volume 9, Issue 4, p.232-40, (2013) Read More / View Supplemental Materials
Abstract
2012
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.Wen, Q., Goldenson B., Silver SJ, Schenone M., Dancik V., Huang Z., Wang LZ, Lewis TA, An WF, Li X., Bray MA, Thiollier C., Diebold L., Gilles L., Vokes MS, Moore CB, Bliss-Moreau M., VerPlank L., Tolliday NJ, Mishra R., et al. Cell, 2012/08/03, Volume 150, Issue 3, p.575-89, (2012) Read More / View Supplemental Materials
Abstract
Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells.Kubicek, S., Gilbert JC, Fomina-Yadlin D., Gitlin AD, Yuan Y., Wagner FF, Holson EB, Luo T., Lewis TA, Taylor B., Gupta S., Shamji AF, Wagner BK, Clemons PA, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2012/04/03, Volume 109, Issue 14, p.5364-9, (2012) Read More / View Supplemental Materials
Abstract
Utility-aware screening with clique-oriented prioritization.Swamidass, SJ, Calhoun BT, Bittker JA, Bodycombe NE, and Clemons PA Journal of chemical information and modeling, 2012/01/23, Volume 52, Issue 1, p.29-37, (2012) Read More / View Supplemental Materials
Abstract
2011
Chemical genomics: probing protein function using small molecules.Wagner, BK, Haggarty SJ, and Clemons PA American journal of pharmacogenomics : genomics-related research in drug development and clinical practice, 2011/12/08, Volume 4, Issue 5, p.313-20, (2011) Read More / View Supplemental Materials
Abstract
A Human Islet Cell Culture System for High-Throughput Screening.Walpita, D., Hasaka T., Spoonamore J., Vetere A., Takane KK, Fomina-Yadlin D., Fiaschi-Taesch N., Shamji A., Clemons PA, Stewart AF, Schreiber SL, and Wagner BK Journal of biomolecular screening, 2011/12/07, (2011) Read More / View Supplemental Materials
Abstract
Master Data Management: Getting your House in Order.Seiler, KP, Bodycombe NE, Hawkins T., Shell R., Lemon A., Souza A., and Clemons PA Combinatorial chemistry & high throughput screening, 2011/11/01, Volume 14, Issue 9, p.749-56, (2011) Read More / View Supplemental Materials
Abstract
A small-molecule screening strategy to identify suppressors of statin myopathy.Wagner, BK, Gilbert TJ, Hanai J., Imamura S., Bodycombe NE, Bon RS, Waldmann H., Clemons PA, Sukhatme VP, and Mootha VK ACS chemical biology, 2011/09/16, Volume 6, Issue 9, p.900-4, (2011) Read More / View Supplemental Materials
Abstract
Enhancing the rate of scaffold discovery with diversity-oriented prioritization.Swamidass, SJ, Calhoun BT, Bittker JA, Bodycombe NE, and Clemons PA Bioinformatics (Oxford, England), 2011/08/15, Volume 27, Issue 16, p.2271-8, (2011) Read More / View Supplemental Materials
Abstract
Quantifying structure and performance diversity for sets of small molecules comprising small-molecule screening collections.Clemons, PA, Wilson JA, Dančík V., Muller S., Carrinski HA, Wagner BK, Koehler AN, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2011/04/26, Volume 108, Issue 17, p.6817-22, (2011) Read More / View Supplemental Materials
Abstract
Route to three-dimensional fragments using diversity-oriented synthesis.Hung, AW, Ramek A., Wang Y., Kaya T., Wilson JA, Clemons PA, and Young DW Proceedings of the National Academy of Sciences of the United States of America, 2011/04/26, Volume 108, Issue 17, p.6799-804, (2011) Read More / View Supplemental Materials
Abstract
Assay of the multiple energy-producing pathways of mammalian cells.Bochner, BR, Siri M., Huang RH, Noble S., Lei XH, Clemons PA, and Wagner BK PloS one, 2011/03/24, Volume 6, Issue 3, p.e18147, (2011) Read More / View Supplemental Materials
Abstract
The binding of fluorophores to proteins depends on the cellular environment.Kim, YK, Lee JS, Bi X., Ha HH, Ng SH, Ahn YH, Lee JJ, Wagner BK, Clemons PA, and Chang YT Angewandte Chemie (International ed. in English), 2011/03/14, Volume 50, Issue 12, p.2761-3, (2011) Read More / View Supplemental Materials
Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes.Shaw, SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A., and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2011/01/11, Volume 108, Issue 2, p.492-7, (2011) Read More / View Supplemental Materials
Abstract
2010
Expanding stereochemical and skeletal diversity using petasis reactions and 1,3-dipolar cycloadditions.Muncipinto, G., Kaya T., Wilson JA, Kumagai N., Clemons PA, and Schreiber SL Organic letters, 2010/11/19, Volume 12, Issue 22, p.5230-3, (2010) Read More / View Supplemental Materials
Abstract
Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles.Clemons, PA, Bodycombe NE, Carrinski HA, Wilson JA, Shamji AF, Wagner BK, Koehler AN, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2010/11/02, Volume 107, Issue 44, p.18787-92, (2010) Read More / View Supplemental Materials
Abstract
Towards patient-based cancer therapeutics.Cancer Target Discovery and Development, Network, Schreiber SL, Shamji AF, Clemons PA, Hon C., Koehler AN, Munoz B., Palmer M., Stern AM, Wagner BK, Powers S., Lowe SW, Guo X., Krasnitz A., Sawey ET, Sordella R., Stein L., Trotman LC, Califano A., Dalla-Favera R., et al. Nature biotechnology, 2010/09/01, Volume 28, Issue 9, p.904-6, (2010) Read More / View Supplemental Materials
Small-molecule inducers of insulin expression in pancreatic alpha-cells.Fomina-Yadlin, D., Kubicek S., Walpita D., Dancik V., Hecksher-Sørensen J., Bittker JA, Sharifnia T., Shamji A., Clemons PA, Wagner BK, and Schreiber SL Proceedings of the National Academy of Sciences of the United States of America, 2010/08/24, Volume 107, Issue 34, p.15099-104, (2010) Read More / View Supplemental Materials
Abstract
Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis.Chou, DH, Bodycombe NE, Carrinski HA, Lewis TA, Clemons PA, Schreiber SL, and Wagner BK ACS chemical biology, 2010/08/20, Volume 5, Issue 8, p.729-34, (2010) Read More / View Supplemental Materials
Abstract
Distinct biological network properties between the targets of natural products and disease genes.Dancík, V., Seiler KP, Young DW, Schreiber SL, and Clemons PA Journal of the American Chemical Society, 2010/07/14, Volume 132, Issue 27, p.9259-61, (2010) Read More / View Supplemental Materials
Abstract
An economic framework to prioritize confirmatory tests after a high-throughput screen.Swamidass, SJ, Bittker JA, Bodycombe NE, Ryder SP, and Clemons PA Journal of biomolecular screening, 2010/07/01, Volume 15, Issue 6, p.680-6, (2010) Read More / View Supplemental Materials
Abstract
Stereochemical and skeletal diversity arising from amino propargylic alcohols.Pizzirani, D., Kaya T., Clemons PA, and Schreiber SL Organic letters, 2010/06/18, Volume 12, Issue 12, p.2822-5, (2010) Read More / View Supplemental Materials
Abstract
2009
Connecting synthetic chemistry decisions to cell and genome biology using small-molecule phenotypic profiling.Wagner, BK, and Clemons PA Current opinion in chemical biology, 2009/12/01, Volume 13, Issue 5-6, p.539-48, (2009) Read More / View Supplemental Materials
Abstract
Alpha shapes applied to molecular shape characterization exhibit novel properties compared to established shape descriptors.Wilson, JA, Bender A., Kaya T., and Clemons PA Journal of chemical information and modeling, 2009/10/01, Volume 49, Issue 10, p.2231-41, (2009) Read More / View Supplemental Materials
Abstract
Using biological performance similarity to inform disaccharide library design.Tanikawa, T., Fridman M., Zhu W., Faulk B., Joseph IC, Kahne D., Wagner BK, and Clemons PA Journal of the American Chemical Society, 2009/04/15, Volume 131, Issue 14, p.5075-83, (2009) Read More / View Supplemental Materials
Abstract
Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries.Kelly, KA, Shaw SY, Nahrendorf M., Kristoff K., Aikawa E., Schreiber SL, Clemons PA, and Weissleder R. Integrative biology : quantitative biosciences from nano to macro, 2009/04/01, Volume 1, Issue 4, p.311-7, (2009) Read More / View Supplemental Materials
Abstract
Cell-Based Assays for High-Throughput ScreeningClemons, PA, Tolliday NJ, and Wagner BK Humana Press, Volume 486, p.1-218, (2009) Read More / View Supplemental Materials
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2008
Using ChemBank to probe chemical biology.Petri Seiler, K., Kuehn H., Pat Happ M., DeCaprio D., and Clemons PA Current protocols in bioinformatics / editoral board, Andreas D. Baxevanis ... [et al.], 2008/06/01, Volume Chapter 14, p.Unit 14.5, (2008) Read More / View Supplemental Materials
Abstract
Chemical Informatics, in Chemical Biology: From Small Molecules to Systems Biology and Drug DesignClemons, PA Wiley-VCH, 2008/04/21, Volume 1-3, p.723-759, (2008) Read More / View Supplemental Materials
Abstract
Small-molecule fluorophores to detect cell-state switching in the context of high-throughput screening.Wagner, BK, Carrinski HA, Ahn YH, Kim YK, Gilbert TJ, Fomina DA, Schreiber SL, Chang YT, and Clemons PA Journal of the American Chemical Society, 2008/04/02, Volume 130, Issue 13, p.4208-9, (2008) Read More / View Supplemental Materials
Abstract
ChemBank: a small-molecule screening and cheminformatics resource database.Seiler, KP, George GA, Happ MP, Bodycombe NE, Carrinski HA, Norton S., Brudz S., Sullivan JP, Muhlich J., Serrano M., Ferraiolo P., Tolliday NJ, Schreiber SL, and Clemons PA Nucleic acids research, 2008/01/01, Volume 36, p.D351-9, (2008) Read More / View Supplemental Materials
Abstract
2007
Chemogenomic data analysis: prediction of small-molecule targets and the advent of biological fingerprint.Bender, A., Young DW, Jenkins JL, Serrano M., Mikhailov D., Clemons PA, and Davies JW Combinatorial chemistry & high throughput screening, 2007/09/01, Volume 10, Issue 8, p.719-31, (2007) Read More / View Supplemental Materials
Abstract
A pipeline for ligand discovery using small-molecule microarrays.Duffner, JL, Clemons PA, and Koehler AN Current opinion in chemical biology, 2007/02/01, Volume 11, Issue 1, p.74-82, (2007) Read More / View Supplemental Materials
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2006
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.Lamb, J., Crawford ED, Peck D., Modell JW, Blat IC, Wrobel MJ, Lerner J., Brunet JP, Subramanian A., Ross KN, Reich M., Hieronymus H., Wei G., Armstrong SA, Haggarty SJ, Clemons PA, Wei R., Carr SA, Lander E. S., and Golub T. R. Science (New York, N.Y.), 2006/09/29, Volume 313, Issue 5795, p.1929-35, (2006) Read More / View Supplemental Materials
Abstract
Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics.Tolliday, N., Clemons PA, Ferraiolo P., Koehler AN, Lewis TA, Li X., Schreiber SL, Gerhard DS, and Eliasof S. Cancer research, 2006/09/15, Volume 66, Issue 18, p.8935-42, (2006) Read More / View Supplemental Materials
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2005
SpectralNET--an application for spectral graph analysis and visualization.Forman, JJ, Clemons PA, Schreiber SL, and Haggarty SJ BMC bioinformatics, 2005/10/19, Volume 6, p.260, (2005) Read More / View Supplemental Materials
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2004
Relationship of stereochemical and skeletal diversity of small molecules to cellular measurement space.Kim, YK, Arai MA, Arai T., Lamenzo JO, Dean EF 3rd, Patterson N., Clemons PA, and Schreiber SL Journal of the American Chemical Society, 2004/11/17, Volume 126, Issue 45, p.14740-5, (2004) Read More / View Supplemental Materials
Abstract
Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors.Haggarty, SJ, Clemons PA, Wong JC, and Schreiber SL Combinatorial chemistry & high throughput screening, 2004/11/01, Volume 7, Issue 7, p.669-76, (2004) Read More / View Supplemental Materials
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Complex phenotypic assays in high-throughput screening.Clemons, PA Current opinion in chemical biology, 2004/06/01, Volume 8, Issue 3, p.334-8, (2004) Read More / View Supplemental Materials
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2003
Chemical genomic profiling of biological networks using graph theory and combinations of small molecule perturbations.Haggarty, SJ, Clemons PA, and Schreiber SL Journal of the American Chemical Society, 2003/09/03, Volume 125, Issue 35, p.10543-5, (2003) Read More / View Supplemental Materials
Abstract
Uncleaved BAP31 in association with A4 protein at the endoplasmic reticulum is an inhibitor of Fas-initiated release of cytochrome c from mitochondria.Wang, B., Nguyen M., Breckenridge DG, Stojanovic M., Clemons PA, Kuppig S., and Shore GC The Journal of biological chemistry, 2003/04/18, Volume 278, Issue 16, p.14461-8, (2003) Read More / View Supplemental Materials
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2002
Synthesis of calcineurin-resistant derivatives of FK506 and selection of compensatory receptors.Clemons, PA, Gladstone BG, Seth A., Chao ED, Foley MA, and Schreiber SL Chemistry & biology, 2002/01/01, Volume 9, Issue 1, p.49-61, (2002) Read More / View Supplemental Materials
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2001
A one-bead, one-stock solution approach to chemical genetics: part 2.Clemons, PA, Koehler AN, Wagner BK, Sprigings TG, Spring DR, King RW, Schreiber SL, and Foley MA Chemistry & biology, 2001/12/01, Volume 8, Issue 12, p.1183-95, (2001) Read More / View Supplemental Materials
Abstract
Exploiting site-site interactions on solid support to generate dimeric molecules.Blackwell, HE, Clemons PA, and Schreiber SL Organic letters, 2001/04/19, Volume 3, Issue 8, p.1185-8, (2001) Read More / View Supplemental Materials
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2000
Be still my beating heart.Clemons, PA Trends in biotechnology, 2000/10/01, Volume 18, Issue 10, p.407, (2000) Read More / View Supplemental Materials
1999
Design and discovery of protein dimerizers.Clemons, PA Current opinion in chemical biology, 1999/02/01, Volume 3, Issue 1, p.112-5, (1999) Read More / View Supplemental Materials
1969
High-throughput identification of phage-derived imaging agents.Kelly, KA, Clemons PA, Yu AM, and Weissleder R. Molecular imaging, 1969/12/31, Volume 5, Issue 1, p.24-30, (1969) Read More / View Supplemental Materials
Abstract
  • Showing 1-69 of 69 Results