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  • Showing 1-21 of 21 Results
2016
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses.Okbay, A., Baselmans BM, De Neve JE, Turley P., Nivard MG, Fontana MA, Meddens SF, Linnér RK, Rietveld CA, Derringer J., Gratten J., Lee JJ, Liu JZ, de Vlaming R., Ahluwalia TS, Buchwald J., Cavadino A., Frazier-Wood AC, Furlotte NA, Garfield V., et al. Nature genetics, 2016/04/18, (2016) Read More / View Supplemental Materials
Abstract
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.Ellinghaus, D., Jostins L., Spain SL, Cortes A., Bethune J., Han B., Park YR, Raychaudhuri S., Pouget JG, Hübenthal M., Folseraas T., Wang Y., Esko T., Metspalu A., Westra HJ, Franke L., Pers TH, Weersma RK, Collij V., D'Amato M., et al. Nature genetics, 2016/03/14, (2016) Read More / View Supplemental Materials
Abstract
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.Lu, Y., Day FR, Gustafsson S., Buchkovich ML, Na J., Bataille V., Cousminer DL, Dastani Z., Drong AW, Esko T., Evans DM, Falchi M., Feitosa MF, Ferreira T., Hedman Å. K., Haring R., Hysi PG, Iles MM, Justice AE, Kanoni S., et al. Nature communications, 2016/02/01, Volume 7, p.10495, (2016) Read More / View Supplemental Materials
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2015
The transcriptional landscape of age in human peripheral blood.Peters, MJ, Joehanes R., Pilling LC, Schurmann C., Conneely KN, Powell J., Reinmaa E., Sutphin GL, Zhernakova A., Schramm K., Wilson YA, Kobes S., Tukiainen T., NABEC/UKBEC Consortium, Ramos YF, Göring HH, Fornage M., Liu Y., Gharib SA, Stranger BE, et al. Nature communications, 2015/10/22, Volume 6, p.8570, (2015) Read More / View Supplemental Materials
Abstract
An integrative systems genetics approach reveals potential causal genes and pathways related to obesity.Kogelman, LJ, Zhernakova DV, Westra HJ, Cirera S., Fredholm M., Franke L., and Kadarmideen HN Genome medicine, 2015/10/20, Volume 7, Issue 1, p.105, (2015) Read More / View Supplemental Materials
Abstract
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.Winkler, TW, Justice AE, Graff M., Barata L., Feitosa MF, Chu S., Czajkowski J., Esko T., Fall T., Kilpeläinen TO, Lu Y., Mägi R., Mihailov E., Pers TH, Rüeger S., Teumer A., Ehret GB, Ferreira T., Heard-Costa NL, Karjalainen J., et al. PLoS genetics, 2015/10/01, Volume 11, Issue 10, p.e1005378, (2015) Read More / View Supplemental Materials
Abstract
Disentangling the Effects of Colocalizing Genomic Annotations to Functionally Prioritize Non-coding Variants within Complex-Trait Loci.Trynka, G., Westra HJ, Slowikowski K., Hu X., Xu H., Stranger BE, Klein RJ, Han B., and Raychaudhuri S. American journal of human genetics, 2015/07/02, Volume 97, Issue 1, p.139-52, (2015) Read More / View Supplemental Materials
Abstract
Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels.Draisma, HH, Pool R., Kobl M., Jansen R., Petersen AK, Vaarhorst AA, Yet I., Haller T., Demirkan A., Esko T., Zhu G., Böhringer S., Beekman M., van Klinken JB, Römisch-Margl W., Prehn C., Adamski J., de Craen AJ, van Leeuwen EM, Amin N., et al. Nature communications, 2015/06/12, Volume 6, p.7208, (2015) Read More / View Supplemental Materials
Abstract
The impact of low-frequency and rare variants on lipid levels.Surakka, I., Horikoshi M., Mägi R., Sarin AP, Mahajan A., Lagou V., Marullo L., Ferreira T., Miraglio B., Timonen S., Kettunen J., Pirinen M., Karjalainen J., Thorleifsson G., Hägg S., Hottenga JJ, Isaacs A., Ladenvall C., Beekman M., Esko T., et al. Nature genetics, 2015/05/11, (2015) Read More / View Supplemental Materials
Abstract
Cell Specific eQTL Analysis without Sorting Cells.Westra, HJ, Arends D., Esko T., Peters MJ, Schurmann C., Schramm K., Kettunen J., Yaghootkar H., Fairfax BP, Andiappan AK, Li Y., Fu J., Karjalainen J., Platteel M., Visschedijk M., Weersma RK, Kasela S., Milani L., Tserel L., Peterson P., et al. PLoS genetics, 2015/05/01, Volume 11, Issue 5, p.e1005223, (2015) Read More / View Supplemental Materials
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Genetic studies of body mass index yield new insights for obesity biology.Locke, AE, Kahali B., Berndt SI, Justice AE, Pers TH, Day FR, Powell C., Vedantam S., Buchkovich ML, Yang J., Croteau-Chonka DC, Esko T., Fall T., Ferreira T., Gustafsson S., Kutalik Z., Luan J., Mägi R., Randall JC, Winkler TW, et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.197-206, (2015) Read More / View Supplemental Materials
Abstract
New genetic loci link adipose and insulin biology to body fat distribution.Shungin, D., Winkler TW, Croteau-Chonka DC, Ferreira T., Locke AE, Mägi R., Strawbridge RJ, Pers TH, Fischer K., Justice AE, Workalemahu T., Wu JM, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C., Gustafsson S., Day FR, Esko T., et al. Nature, 2015/02/12, Volume 518, Issue 7538, p.187-96, (2015) Read More / View Supplemental Materials
Abstract
Biological interpretation of genome-wide association studies using predicted gene functions.Pers, TH, Karjalainen JM, Chan Y., Westra HJ, Wood AR, Yang J., Lui JC, Vedantam S., Gustafsson S., Esko T., Frayling T., Speliotes EK, Genetic Investigation of ANthropometric Traits(GIANT) Consortium, Boehnke M., Raychaudhuri S., Fehrmann RS, Hirschhorn JN, and Franke L. Nature communications, 2015/01/19, Volume 6, p.5890, (2015) Read More / View Supplemental Materials
Abstract
Gene expression analysis identifies global gene dosage sensitivity in cancer.Fehrmann, RS, Karjalainen JM, Krajewska M., Westra HJ, Maloney D., Simeonov A., Pers TH, Hirschhorn JN, Jansen RC, Schultes EA, van Haagen HH, de Vries EG, Te Meerman GJ, Wijmenga C., van Vugt MA, and Franke L. Nature genetics, 2015/01/12, (2015) Read More / View Supplemental Materials
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2014
Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis.Benyamin, B., Esko T., Ried JS, Radhakrishnan A., Vermeulen SH, Traglia M., Gögele M., Anderson D., Broer L., Podmore C., Luan J., Kutalik Z., Sanna S., van der Meer P., Tanaka T., Wang F., Westra HJ, Franke L., Mihailov E., Milani L., et al. Nature communications, 2014/10/29, Volume 5, p.4926, (2014) Read More / View Supplemental Materials
Abstract
Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption.The Coffee and Caffeine Genetics, Consortium, Cornelis MC, Byrne EM, Esko T., Nalls MA, Ganna A., Paynter N., Monda KL, Amin N., Fischer K., Renstrom F., Ngwa JS, Huikari V., Cavadino A., Nolte IM, Teumer A., Yu K., Marques-Vidal P., Rawal R., Manichaikul A., et al. Molecular psychiatry, 2014/10/07, (2014) Read More / View Supplemental Materials
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Defining the role of common variation in the genomic and biological architecture of adult human height.Wood, AR, Esko T., Yang J., Vedantam S., Pers TH, Gustafsson S., Chu AY, Estrada K., Luan J., Kutalik Z., Amin N., Buchkovich ML, Croteau-Chonka DC, Day FR, Duan Y., Fall T., Fehrmann R., Ferreira T., Jackson AU, Karjalainen J., et al. Nature genetics, 2014/10/05, (2014) Read More / View Supplemental Materials
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Hemani et al. reply.Hemani, G., Shakhbazov K., Westra HJ, Esko T., Henders AK, McRae AF, Yang J., Gibson G., Martin NG, Metspalu A., Franke L., Montgomery GW, Visscher PM, and Powell JE Nature, 2014/10/02, Volume 514, Issue 7520, p.E5-6, (2014) Read More / View Supplemental Materials
Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'Deelen, P., Menelaou A., van Leeuwen EM, Kanterakis A., van Dijk F., Medina-Gomez C., Francioli LC, Hottenga JJ, Karssen LC, Estrada K., Kreiner-Møller E., Rivadeneira F., van Setten J., Gutierrez-Achury J., Westra HJ, Franke L., van Enckevort D., Dijkstra M., Byelas H., van Duijn CM, et al. European journal of human genetics : EJHG, 2014/06/04, (2014) Read More / View Supplemental Materials
Abstract
Detection and replication of epistasis influencing transcription in humans.Hemani, G., Shakhbazov K., Westra HJ, Esko T., Henders AK, McRae AF, Yang J., Gibson G., Martin NG, Metspalu A., Franke L., Montgomery GW, Visscher PM, and Powell JE Nature, 2014/02/26, (2014) Read More / View Supplemental Materials
Abstract
2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery.Okada, Y., Wu D., Trynka G., Raj T., Terao C., Ikari K., Kochi Y., Ohmura K., Suzuki A., Yoshida S., Graham RR, Manoharan A., Ortmann W., Bhangale T., Denny JC, Carroll RJ, Eyler AE, Greenberg JD, Kremer JM, Pappas DA, et al. Nature, 2013/12/25, (2013) Read More / View Supplemental Materials
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  • Showing 1-21 of 21 Results