You are here

Home » Publications

FGI

Tracing the Evolutionary History and Global Expansion of Candida auris Using Population Genomic Analyses.
N. A. Chow, Muñoz, J. F. , Gade, L. , Berkow, E. L. , Li, X. , Welsh, R. M. , Forsberg, K. , Lockhart, S. R. , Adam, R. , Alanio, A. , Alastruey-Izquierdo, A. , Althawadi, S. , Araúz, A. Belén, Ben-Ami, R. , Bharat, A. , Calvo, B. , Desnos-Ollivier, M. , Escandón, P. , Gardam, D. , Gunturu, R. , Heath, C. H. , Kurzai, O. , Martin, R. , Litvintseva, A. P. , and Cuomo, C. A. , “Tracing the Evolutionary History and Global Expansion of Candida auris Using Population Genomic Analyses.”, mBio, vol. 11, no. 2, 2020.
Genomic diversity of the human pathogen Paracoccidioides across the South American continent.
Mde Melo Teixeira, Cattana, M. Emilia, Matute, D. R. , Muñoz, J. F. , Arechavala, A. , Isbell, K. , Schipper, R. , Santiso, G. , Tracogna, F. , Sosa, Mde Los Án, Cech, N. , Alvarado, P. , Barreto, L. , Chacón, Y. , Ortellado, J. , de Lima, C. Mendes, Chang, M. Rodrigues, Nino-Vega, G. , Yasuda, M. Aparecida, Felipe, M. Sueli Soar, Negroni, R. , Cuomo, C. A. , Barker, B. , and Giusiano, G. , “Genomic diversity of the human pathogen Paracoccidioides across the South American continent.”, Fungal Genet Biol, vol. 140, p. 103395, 2020.
Tracking a Global Threat: a New Genotyping Method for Candida auris.
C. A. Cuomo and Alanio, A. , “Tracking a Global Threat: a New Genotyping Method for Candida auris.”, mBio, vol. 11, no. 2, 2020.
Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Species.
L. Ma, Chen, Z. , Huang, D. Wei, Cissé, O. H. , Rothenburger, J. L. , Latinne, A. , Bishop, L. , Blair, R. , Brenchley, J. M. , Chabé, M. , Deng, X. , Hirsch, V. , Keesler, R. , Kutty, G. , Liu, Y. , Margolis, D. , Morand, S. , Pahar, B. , Peng, L. , Van Rompay, K. K. A. , Song, X. , Song, J. , Sukura, A. , Thapar, S. , Wang, H. , Weissenbacher-Lang, C. , Xu, J. , Lee, C. - H. , Jardine, C. , Lempicki, R. A. , Cushion, M. T. , Cuomo, C. A. , and Kovacs, J. A. , “Diversity and Complexity of the Large Surface Protein Family in the Compacted Genomes of Multiple Species.”, mBio, vol. 11, no. 2, 2020.
Human Blastomycosis in South Africa Caused by and sp. nov., 1967 to 2014.
T. G. Maphanga, Birkhead, M. , Muñoz, J. F. , Allam, M. , Zulu, T. G. , Cuomo, C. A. , Schwartz, I. S. , Ismail, A. , Naicker, S. D. , Mpembe, R. S. , Corcoran, C. , de Hoog, S. , Kenyon, C. , Borman, A. M. , Frean, J. A. , and Govender, N. P. , “Human Blastomycosis in South Africa Caused by and sp. nov., 1967 to 2014.”, J Clin Microbiol, vol. 58, no. 3, 2020.
Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase.
S. Catania, Dumesic, P. A. , Pimentel, H. , Nasif, A. , Stoddard, C. I. , Burke, J. E. , Diedrich, J. K. , Cooke, S. , Shea, T. , Gienger, E. , Lintner, R. , Yates, J. R. , Hajkova, P. , Narlikar, G. J. , Cuomo, C. A. , Pritchard, J. K. , and Madhani, H. D. , “Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase.”, Cell, vol. 180, no. 2, pp. 263-277.e20, 2020.
Complete Genome Sequences for Two Clinical Isolates from Northern and Southern Vietnam.
C. A. Cuomo, Shea, T. , Nguyen, T. , Ashton, P. , Perfect, J. , and Le, T. , “Complete Genome Sequences for Two Clinical Isolates from Northern and Southern Vietnam.”, Microbiol Resour Announc, vol. 9, no. 2, 2020.
Landscape of gene expression variation of natural isolates of in response to biologically relevant stresses.
C. - H. Yu, Chen, Y. , Desjardins, C. A. , Tenor, J. L. , Toffaletti, D. L. , Giamberardino, C. , Litvintseva, A. , Perfect, J. R. , and Cuomo, C. A. , “Landscape of gene expression variation of natural isolates of in response to biologically relevant stresses.”, Microb Genom, vol. 6, no. 1, 2020.
A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands.
R. A. Farrer, Chang, M. , Davis, M. J. , van Dorp, L. , Yang, D. - H. , Shea, T. , Sewell, T. R. , Meyer, W. , Balloux, F. , Edwards, H. M. , Chanda, D. , Kwenda, G. , Vanhove, M. , Chang, Y. C. , Cuomo, C. A. , Fisher, M. C. , and Kwon-Chung, K. J. , “A New Lineage of Cryptococcus gattii (VGV) Discovered in the Central Zambezian Miombo Woodlands.”, mBio, vol. 10, no. 6, 2019.
Identification of Candida auris by Use of the Updated Vitek 2 Yeast Identification System, Version 8.01: a Multilaboratory Evaluation Study.
G. Ambaraghassi, Dufresne, P. J. , Dufresne, S. F. , Vallières, É. , Muñoz, J. F. , Cuomo, C. A. , Berkow, E. L. , Lockhart, S. R. , and Luong, M. - L. , “Identification of Candida auris by Use of the Updated Vitek 2 Yeast Identification System, Version 8.01: a Multilaboratory Evaluation Study.”, J Clin Microbiol, vol. 57, no. 11, 2019.
Future-Proofing Your Genome Assembly for Reproducibility and Clarity.
D. A. Baltrus, Cuomo, C. A. , Dennehy, J. J. , Hotopp, J. C. Dunning, Maresca, J. A. , Newton, I. L. G. , Rasko, D. A. , Rokas, A. , Roux, S. , and Stajich, J. E. , “Future-Proofing Your Genome Assembly for Reproducibility and Clarity.”, Microbiol Resour Announc, vol. 8, no. 36, 2019.
Emergomyces: The global rise of new dimorphic fungal pathogens.
I. S. Schwartz, Govender, N. P. , Sigler, L. , Jiang, Y. , Maphanga, T. G. , Toplis, B. , Botha, A. , Dukik, K. , J Hoving, C. , Muñoz, J. F. , de Hoog, S. , Cuomo, C. A. , Colebunders, R. , and Kenyon, C. , “Emergomyces: The global rise of new dimorphic fungal pathogens.”, PLoS Pathog, vol. 15, no. 9, p. e1007977, 2019.
Genome Sequence for Candida albicans Clinical Oral Isolate 529L.
C. A. Cuomo, Fanning, S. , Gujja, S. , Zeng, Q. , Naglik, J. R. , Filler, S. G. , and Mitchell, A. P. , “Genome Sequence for Candida albicans Clinical Oral Isolate 529L.”, Microbiol Resour Announc, vol. 8, no. 25, 2019.
Genetic and Genomic Analyses Reveal Boundaries between Species Closely Related to Pathogens.
A. Ryan Passer, Coelho, M. A. , Billmyre, R. Blake, Nowrousian, M. , Mittelbach, M. , Yurkov, A. M. , Averette, A. Floyd, Cuomo, C. A. , Sun, S. , and Heitman, J. , “Genetic and Genomic Analyses Reveal Boundaries between Species Closely Related to Pathogens.”, mBio, vol. 10, no. 3, 2019.
Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans.
J. F. Muñoz, Delorey, T. , Ford, C. B. , Li, B. Yu, Thompson, D. A. , Rao, R. P. , and Cuomo, C. A. , “Coordinated host-pathogen transcriptional dynamics revealed using sorted subpopulations and single macrophages infected with Candida albicans.”, Nat Commun, vol. 10, no. 1, p. 1607, 2019.
Genome Sequence of the Black Yeast Exophiala lecanii-corni.
Z. Schultzhaus, Cuomo, C. A. , and Wang, Z. , “Genome Sequence of the Black Yeast Exophiala lecanii-corni.”, Microbiol Resour Announc, vol. 8, no. 10, 2019.
Genetic Analysis of Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance.
S. Hu Kim, Iyer, K. R. , Pardeshi, L. , Muñoz, J. F. , Robbins, N. , Cuomo, C. A. , Wong, K. Ho, and Cowen, L. E. , “Genetic Analysis of Implicates Hsp90 in Morphogenesis and Azole Tolerance and Cdr1 in Azole Resistance.”, MBio, vol. 10, no. 1, 2019.
Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans.
K. C. Reddy, Dror, T. , Underwood, R. S. , Osman, G. A. , Elder, C. R. , Desjardins, C. A. , Cuomo, C. A. , Barkoulas, M. , and Troemel, E. R. , “Antagonistic paralogs control a switch between growth and pathogen resistance in C. elegans.”, PLoS Pathog, vol. 15, no. 1, p. e1007528, 2019.
Recovered From Olive Trees () in Turkey Reveal Allopatry With African and South American Lineages.
Ç. Ergin, Şengül, M. , Aksoy, L. , Döğen, A. , Sun, S. , Averette, A. F. , Cuomo, C. A. , Seyedmousavi, S. , Heitman, J. , and Ilkit, M. , “ Recovered From Olive Trees () in Turkey Reveal Allopatry With African and South American Lineages.”, Front Cell Infect Microbiol, vol. 9, p. 384, 2019.
Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species.
J. F. Muñoz, Gade, L. , Chow, N. A. , Loparev, V. N. , Juieng, P. , Berkow, E. L. , Farrer, R. A. , Litvintseva, A. P. , and Cuomo, C. A. , “Genomic insights into multidrug-resistance, mating and virulence in Candida auris and related emerging species.”, Nat Commun, vol. 9, no. 1, p. 5346, 2018.
Transcriptional Heterogeneity of VGII Compared with Non-VGII Lineages Underpins Key Pathogenicity Pathways.
R. A. Farrer, Ford, C. B. , Rhodes, J. , Delorey, T. , May, R. C. , Fisher, M. C. , Cloutman-Green, E. , Balloux, F. , and Cuomo, C. A. , “Transcriptional Heterogeneity of VGII Compared with Non-VGII Lineages Underpins Key Pathogenicity Pathways.”, mSphere, vol. 3, no. 5, 2018.
Phenotypic Variability Correlates with Clinical Outcome in Isolates Obtained from Botswanan HIV/AIDS Patients.
K. E. Fernandes, Brockway, A. , Haverkamp, M. , Cuomo, C. A. , van Ogtrop, F. , Perfect, J. R. , and Carter, D. A. , “Phenotypic Variability Correlates with Clinical Outcome in Isolates Obtained from Botswanan HIV/AIDS Patients.”, MBio, vol. 9, no. 5, 2018.
Genomic characterization of recurrent mold infections in thoracic transplant recipients.
J. A. Messina, Wolfe, C. R. , Hemmersbach-Miller, M. , Milano, C. , Todd, J. L. , Reynolds, J. , Alexander, B. D. , Schell, W. A. , Cuomo, C. A. , and Perfect, J. R. , “Genomic characterization of recurrent mold infections in thoracic transplant recipients.”, Transpl Infect Dis, vol. 20, no. 5, p. e12935, 2018.
Pathways of Pathogenicity: Transcriptional Stages of Germination in the Fatal Fungal Pathogen.
P. C. S. Sephton-Clark, Muñoz, J. F. , Ballou, E. R. , Cuomo, C. A. , and Voelz, K. , “Pathways of Pathogenicity: Transcriptional Stages of Germination in the Fatal Fungal Pathogen.”, mSphere, vol. 3, no. 5, 2018.
Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen.
I. V. Ene, Farrer, R. A. , Hirakawa, M. P. , Agwamba, K. , Cuomo, C. A. , and Bennett, R. J. , “Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen.”, Proc Natl Acad Sci U S A, vol. 115, no. 37, pp. E8688-E8697, 2018.
Author Correction: Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris.
J. Rhodes, Abdolrasouli, A. , Farrer, R. A. , Cuomo, C. A. , Aanensen, D. M. , Armstrong-James, D. , Fisher, M. C. , and Schelenz, S. , “Author Correction: Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris.”, Emerg Microbes Infect, vol. 7, no. 1, p. 104, 2018.
Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen .
O. H. Cissé, Ma, L. , Huang, D. Wei, Khil, P. P. , Dekker, J. P. , Kutty, G. , Bishop, L. , Liu, Y. , Deng, X. , Hauser, P. M. , Pagni, M. , Hirsch, V. , Lempicki, R. A. , Stajich, J. E. , Cuomo, C. A. , and Kovacs, J. A. , “Comparative Population Genomics Analysis of the Mammalian Fungal Pathogen .”, mBio, vol. 9, no. 3, 2018.
Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators.
B. Hommel, Mukaremera, L. , Cordero, R. J. B. , Coelho, C. , Desjardins, C. A. , Sturny-Leclère, A. , Janbon, G. , Perfect, J. R. , Fraser, J. A. , Casadevall, A. , Cuomo, C. A. , Dromer, F. , Nielsen, K. , and Alanio, A. , “Titan cells formation in Cryptococcus neoformans is finely tuned by environmental conditions and modulated by positive and negative genetic regulators.”, PLoS Pathog, vol. 14, no. 5, p. e1006982, 2018.
Whole-Genome Analysis Illustrates Global Clonal Population Structure of the Ubiquitous Dermatophyte Pathogen .
G. F. Persinoti, Martinez, D. A. , Li, W. , Döğen, A. , R Billmyre, B. , Averette, A. , Goldberg, J. M. , Shea, T. , Young, S. , Zeng, Q. , Oliver, B. G. , Barton, R. , Metin, B. , Hilmioğlu-Polat, S. , Ilkit, M. , Gräser, Y. , Martinez-Rossi, N. M. , White, T. C. , Heitman, J. , and Cuomo, C. A. , “Whole-Genome Analysis Illustrates Global Clonal Population Structure of the Ubiquitous Dermatophyte Pathogen .”, Genetics, vol. 208, no. 4, pp. 1657-1669, 2018.
Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris.
J. Rhodes, Abdolrasouli, A. , Farrer, R. A. , Cuomo, C. A. , Aanensen, D. M. , Armstrong-James, D. , Fisher, M. C. , and Schelenz, S. , “Genomic epidemiology of the UK outbreak of the emerging human fungal pathogen Candida auris.”, Emerg Microbes Infect, vol. 7, no. 1, p. 43, 2018.
RNAi is a critical determinant of centromere evolution in closely related fungi.
V. Yadav, Sun, S. , R Billmyre, B. , Thimmappa, B. C. , Shea, T. , Lintner, R. , Bakkeren, G. , Cuomo, C. A. , Heitman, J. , and Sanyal, K. , “RNAi is a critical determinant of centromere evolution in closely related fungi.”, Proc Natl Acad Sci U S A, vol. 115, no. 12, pp. 3108-3113, 2018.
Genomic Understanding of an Infectious Brain Disease from the Desert.
L. F. Moreno, Ahmed, A. A. O. , Brankovics, B. , Cuomo, C. A. , Menken, S. B. J. , Taj-Aldeen, S. J. , Faidah, H. , J Stielow, B. , Teixeira, Mde M. , Prenafeta-Boldú, F. X. , Vicente, V. A. , and de Hoog, S. , “Genomic Understanding of an Infectious Brain Disease from the Desert.”, G3 (Bethesda), vol. 8, no. 3, pp. 909-922, 2018.
: An Intricate Dance of Anther Smut and Its Host.
S. San Toh, Chen, Z. , Rouchka, E. C. , Schultz, D. J. , Cuomo, C. A. , and Perlin, M. H. , “: An Intricate Dance of Anther Smut and Its Host.”, G3 (Bethesda), vol. 8, no. 2, pp. 505-518, 2018.
Advances in Cryptococcus genomics: insights into the evolution of pathogenesis.
C. A. Cuomo, Rhodes, J. , and Desjardins, C. A. , “Advances in Cryptococcus genomics: insights into the evolution of pathogenesis.”, Mem Inst Oswaldo Cruz, vol. 113, no. 7, p. e170473, 2018.
Whole Genome Sequence of the Heterozygous Clinical Isolate 81-B-5.
C. A. Cuomo, Shea, T. , Yang, B. , Rao, R. , and Forche, A. , “Whole Genome Sequence of the Heterozygous Clinical Isolate 81-B-5.”, G3 (Bethesda), vol. 7, no. 9, pp. 2883-2889, 2017.
Tracing Genetic Exchange and Biogeography of var. at the Global Population Level.
J. Rhodes, Desjardins, C. A. , Sykes, S. M. , Beale, M. A. , Vanhove, M. , Sakthikumar, S. , Chen, Y. , Gujja, S. , Saif, S. , Chowdhary, A. , Lawson, D. John, Ponzio, V. , Colombo, A. Lopes, Meyer, W. , Engelthaler, D. M. , Hagen, F. , Illnait-Zaragozi, M. Teresa, Alanio, A. , Vreulink, J. - M. , Heitman, J. , Perfect, J. R. , Litvintseva, A. P. , Bicanic, T. , Harrison, T. S. , Fisher, M. C. , and Cuomo, C. A. , “Tracing Genetic Exchange and Biogeography of var. at the Global Population Level.”, Genetics, vol. 207, no. 1, pp. 327-346, 2017.
Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination.
S. Sun, Yadav, V. , R Billmyre, B. , Cuomo, C. A. , Nowrousian, M. , Wang, L. , Souciet, J. - L. , Boekhout, T. , Porcel, B. , Wincker, P. , Granek, J. A. , Sanyal, K. , and Heitman, J. , “Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination.”, PLoS Biol, vol. 15, no. 8, p. e2002527, 2017.
Population genomics and the evolution of virulence in the fungal pathogen .
C. A. Desjardins, Giamberardino, C. , Sykes, S. M. , Yu, C. - H. , Tenor, J. L. , Chen, Y. , Yang, T. , Jones, A. M. , Sun, S. , Haverkamp, M. R. , Heitman, J. , Litvintseva, A. P. , Perfect, J. R. , and Cuomo, C. A. , “Population genomics and the evolution of virulence in the fungal pathogen .”, Genome Res, vol. 27, no. 7, pp. 1207-1219, 2017.
Novel taxa of thermally dimorphic systemic pathogens in the Ajellomycetaceae (Onygenales).
K. Dukik, Muñoz, J. F. , Jiang, Y. , Feng, P. , Sigler, L. , J Stielow, B. , Freeke, J. , Jamalian, A. , van den Ende, B. Gerrits, McEwen, J. G. , Clay, O. K. , Schwartz, I. S. , Govender, N. P. , Maphanga, T. G. , Cuomo, C. A. , Moreno, L. F. , Kenyon, C. , Borman, A. M. , and de Hoog, S. , “Novel taxa of thermally dimorphic systemic pathogens in the Ajellomycetaceae (Onygenales).”, Mycoses, vol. 60, no. 5, pp. 296-309, 2017.
Genomic innovations linked to infection strategies across emerging pathogenic chytrid fungi.
R. A. Farrer, Martel, A. , Verbrugghe, E. , Abouelleil, A. , Ducatelle, R. , Longcore, J. E. , James, T. Y. , Pasmans, F. , Fisher, M. C. , and Cuomo, C. A. , “Genomic innovations linked to infection strategies across emerging pathogenic chytrid fungi.”, Nat Commun, vol. 8, p. 14742, 2017.
Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii.
Y. Chen, Farrer, R. A. , Giamberardino, C. , Sakthikumar, S. , Jones, A. , Yang, T. , Tenor, J. L. , Wagih, O. , Van Wyk, M. , Govender, N. P. , Mitchell, T. G. , Litvintseva, A. P. , Cuomo, C. A. , and Perfect, J. R. , “Microevolution of Serial Clinical Isolates of Cryptococcus neoformans var. grubii and C. gattii.”, MBio, vol. 8, no. 2, 2017.
Exploring the genomic diversity of black yeasts and relatives (Chaetothyriales, Ascomycota).
M. M. Teixeira, Moreno, L. F. , Stielow, B. J. , Muszewska, A. , Hainaut, M. , Gonzaga, L. , Abouelleil, A. , Patané, J. S. L. , Priest, M. , Souza, R. , Young, S. , Ferreira, K. S. , Zeng, Q. , da Cunha, M. M. L. , Gladki, A. , Barker, B. , Vicente, V. A. , de Souza, E. M. , Almeida, S. , Henrissat, B. , Vasconcelos, A. T. R. , Deng, S. , Voglmayr, H. , Moussa, T. A. A. , Gorbushina, A. , Felipe, M. S. S. , Cuomo, C. A. , and G de Hoog, S. , “Exploring the genomic diversity of black yeasts and relatives (Chaetothyriales, Ascomycota).”, Stud Mycol, vol. 86, pp. 1-28, 2017.
Paracoccidioides spp. catalases and their role in antioxidant defense against host defense responses.
D. Tamayo, Muñoz, J. F. , Almeida, A. J. , Puerta, J. D. , Restrepo, Á. , Cuomo, C. A. , McEwen, J. G. , and Hernández, O. , “Paracoccidioides spp. catalases and their role in antioxidant defense against host defense responses.”, Fungal Genet Biol, vol. 100, pp. 22-32, 2017.
Comparative Analysis Highlights Variable Genome Content of Wheat Rusts and Divergence of the Mating Loci.
C. A. Cuomo, Bakkeren, G. , Khalil, H. Badr, Panwar, V. , Joly, D. , Linning, R. , Sakthikumar, S. , Song, X. , Adiconis, X. , Fan, L. , Goldberg, J. M. , Levin, J. Z. , Young, S. , Zeng, Q. , Anikster, Y. , Bruce, M. , Wang, M. , Yin, C. , McCallum, B. , Szabo, L. J. , Hulbert, S. , Chen, X. , and Fellers, J. P. , “Comparative Analysis Highlights Variable Genome Content of Wheat Rusts and Divergence of the Mating Loci.”, G3 (Bethesda), vol. 7, no. 2, pp. 361-376, 2017.
Zinc Cluster Transcription Factors Alter Virulence in Candida albicans.
L. Issi, Farrer, R. A. , Pastor, K. , Landry, B. , Delorey, T. , Bell, G. W. , Thompson, D. A. , Cuomo, C. A. , and Rao, R. P. , “Zinc Cluster Transcription Factors Alter Virulence in Candida albicans.”, Genetics, vol. 205, no. 2, pp. 559-576, 2017.
Transcriptional analysis of mating and pre-infection stages of the anther smut, Microbotryum lychnidis-dioicae.
S. San Toh, Chen, Z. , Schultz, D. J. , Cuomo, C. A. , and Perlin, M. H. , “Transcriptional analysis of mating and pre-infection stages of the anther smut, Microbotryum lychnidis-dioicae.”, Microbiology, 2017.
Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses.
S. R. Lockhart, Etienne, K. A. , Vallabhaneni, S. , Farooqi, J. , Chowdhary, A. , Govender, N. P. , Colombo, A. Lopes, Calvo, B. , Cuomo, C. A. , Desjardins, C. A. , Berkow, E. L. , Castanheira, M. , Magobo, R. E. , Jabeen, K. , Asghar, R. J. , Meis, J. F. , Jackson, B. , Chiller, T. , and Litvintseva, A. P. , “Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents Confirmed by Whole-Genome Sequencing and Epidemiological Analyses.”, Clin Infect Dis, vol. 64, no. 2, pp. 134-140, 2017.
Harnessing Whole Genome Sequencing in Medical Mycology.
C. A. Cuomo, “Harnessing Whole Genome Sequencing in Medical Mycology.”, Curr Fungal Infect Rep, vol. 11, no. 2, pp. 52-59, 2017.
The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis.
K. J. Kwon-Chung, Bennett, J. E. , Wickes, B. L. , Meyer, W. , Cuomo, C. A. , Wollenburg, K. R. , Bicanic, T. A. , Castañeda, E. , Chang, Y. C. , Chen, J. , Cogliati, M. , Dromer, F. , Ellis, D. , Filler, S. G. , Fisher, M. C. , Harrison, T. S. , Holland, S. M. , Kohno, S. , Kronstad, J. W. , Lazera, M. , Levitz, S. M. , Lionakis, M. S. , May, R. C. , Ngamskulrongroj, P. , Pappas, P. G. , Perfect, J. R. , Rickerts, V. , Sorrell, T. C. , Walsh, T. J. , Williamson, P. R. , Xu, J. , Zelazny, A. M. , and Casadevall, A. , “The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis.”, mSphere, vol. 2, no. 1, 2017.
Comparative Genomics Integrated with Association Analysis Identifies Candidate Effector Genes Corresponding to Lr20 in Phenotype-Paired Puccinia triticina Isolates from Australia.
J. Qin Wu, Sakthikumar, S. , Dong, C. , Zhang, P. , Cuomo, C. A. , and Park, R. F. , “Comparative Genomics Integrated with Association Analysis Identifies Candidate Effector Genes Corresponding to Lr20 in Phenotype-Paired Puccinia triticina Isolates from Australia.”, Front Plant Sci, vol. 8, p. 148, 2017.
Microevolutionary traits and comparative population genomics of the emerging pathogenic fungus Cryptococcus gattii.
R. A. Farrer, Voelz, K. , Henk, D. A. , Johnston, S. A. , Fisher, M. C. , May, R. C. , and Cuomo, C. A. , “Microevolutionary traits and comparative population genomics of the emerging pathogenic fungus Cryptococcus gattii.”, Philos Trans R Soc Lond B Biol Sci, vol. 371, no. 1709, 2016.
A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues.
M. Z. Anderson, Porman, A. M. , Wang, N. , Mancera, E. , Huang, D. , Cuomo, C. A. , and Bennett, R. J. , “A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues.”, PLoS Genet, vol. 12, no. 10, p. e1006353, 2016.
Genome Sequence of Spizellomyces punctatus.
C. Russ, B Lang, F. , Chen, Z. , Gujja, S. , Shea, T. , Zeng, Q. , Young, S. , Cuomo, C. A. , and Nusbaum, C. , “Genome Sequence of Spizellomyces punctatus.”, Genome Announc, vol. 4, no. 4, 2016.
Lower prevalence but similar fitness in a parasitic fungus at higher radiation levels near Chernobyl.
G. Aguileta, Badouin, H. , Hood, M. E. , Møller, A. P. , Le Prieur, S. , Snirc, A. , Siguenza, S. , Mousseau, T. A. , Shykoff, J. A. , Cuomo, C. A. , and Giraud, T. , “Lower prevalence but similar fitness in a parasitic fungus at higher radiation levels near Chernobyl.”, Mol Ecol, vol. 25, no. 14, pp. 3370-83, 2016.
Use of Multiple Sequencing Technologies To Produce a High-Quality Genome of the Fungus Pseudogymnoascus destructans, the Causative Agent of Bat White-Nose Syndrome.
K. P. Drees, Palmer, J. M. , Sebra, R. , Lorch, J. M. , Chen, C. , Wu, C. - C. , Bok, J. Woo, Keller, N. P. , Blehert, D. S. , Cuomo, C. A. , Lindner, D. L. , and Foster, J. T. , “Use of Multiple Sequencing Technologies To Produce a High-Quality Genome of the Fungus Pseudogymnoascus destructans, the Causative Agent of Bat White-Nose Syndrome.”, Genome Announc, vol. 4, no. 3, 2016.
Intracellular Action of a Secreted Peptide Required for Fungal Virulence.
C. M. Homer, Summers, D. K. , Goranov, A. I. , Clarke, S. C. , Wiesner, D. L. , Diedrich, J. K. , Moresco, J. J. , Toffaletti, D. , Upadhya, R. , Caradonna, I. , Petnic, S. , Pessino, V. , Cuomo, C. A. , Lodge, J. K. , Perfect, J. , Yates, J. R. , Nielsen, K. , Craik, C. S. , and Madhani, H. D. , “Intracellular Action of a Secreted Peptide Required for Fungal Virulence.”, Cell Host Microbe, vol. 19, no. 6, pp. 849-64, 2016.
Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans.
M. D. Leach, Farrer, R. A. , Tan, K. , Miao, Z. , Walker, L. A. , Cuomo, C. A. , Wheeler, R. T. , Brown, A. J. P. , Wong, K. Ho, and Cowen, L. E. , “Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans.”, Nat Commun, vol. 7, p. 11704, 2016.
Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts.
L. Ma, Chen, Z. , Huang, D. Wei, Kutty, G. , Ishihara, M. , Wang, H. , Abouelleil, A. , Bishop, L. , Davey, E. , Deng, R. , Deng, X. , Fan, L. , Fantoni, G. , Fitzgerald, M. , Gogineni, E. , Goldberg, J. M. , Handley, G. , Hu, X. , Huber, C. , Jiao, X. , Jones, K. , Levin, J. Z. , Liu, Y. , Macdonald, P. , Melnikov, A. , Raley, C. , Sassi, M. , Sherman, B. T. , Song, X. , Sykes, S. , Tran, B. , Walsh, L. , Xia, Y. , Yang, J. , Young, S. , Zeng, Q. , Zheng, X. , Stephens, R. , Nusbaum, C. , Birren, B. W. , Azadi, P. , Lempicki, R. A. , Cuomo, C. A. , and Kovacs, J. A. , “Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts.”, Nat Commun, vol. 7, p. 10740, 2016.
Genome Diversity, Recombination, and Virulence across the Major Lineages of Paracoccidioides.
J. F. Muñoz, Farrer, R. A. , Desjardins, C. A. , Gallo, J. E. , Sykes, S. , Sakthikumar, S. , Misas, E. , Whiston, E. A. , Bagagli, E. , Soares, C. M. A. , Teixeira, Mde M. , Taylor, J. W. , Clay, O. K. , McEwen, J. G. , and Cuomo, C. A. , “Genome Diversity, Recombination, and Virulence across the Major Lineages of Paracoccidioides.”, mSphere, vol. 1, no. 5, 2016.
The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia.
J. F. Muñoz, Gauthier, G. M. , Desjardins, C. A. , Gallo, J. E. , Holder, J. , Sullivan, T. D. , Marty, A. J. , Carmen, J. C. , Chen, Z. , Ding, L. , Gujja, S. , Magrini, V. , Misas, E. , Mitreva, M. , Priest, M. , Saif, S. , Whiston, E. A. , Young, S. , Zeng, Q. , Goldman, W. E. , Mardis, E. R. , Taylor, J. W. , McEwen, J. G. , Clay, O. K. , Klein, B. S. , and Cuomo, C. A. , “The Dynamic Genome and Transcriptome of the Human Fungal Pathogen Blastomyces and Close Relative Emmonsia.”, PLoS Genet, vol. 11, no. 10, p. e1005493, 2015.
Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii.
R. A. Farrer, Desjardins, C. A. , Sakthikumar, S. , Gujja, S. , Saif, S. , Zeng, Q. , Chen, Y. , Voelz, K. , Heitman, J. , May, R. C. , Fisher, M. C. , and Cuomo, C. A. , “Genome Evolution and Innovation across the Four Major Lineages of Cryptococcus gattii.”, MBio, vol. 6, no. 5, pp. e00868-15, 2015.
Sex and parasites: genomic and transcriptomic analysis of Microbotryum lychnidis-dioicae, the biotrophic and plant-castrating anther smut fungus.
M. H. Perlin, Amselem, J. , Fontanillas, E. , San Toh, S. , Chen, Z. , Goldberg, J. , Duplessis, S. , Henrissat, B. , Young, S. , Zeng, Q. , Aguileta, G. , Petit, E. , Badouin, H. , Andrews, J. , Razeeq, D. , Gabaldón, T. , Quesneville, H. , Giraud, T. , Hood, M. E. , Schultz, D. J. , and Cuomo, C. A. , “Sex and parasites: genomic and transcriptomic analysis of Microbotryum lychnidis-dioicae, the biotrophic and plant-castrating anther smut fungus.”, BMC Genomics, vol. 16, p. 461, 2015.
Contrasting host-pathogen interactions and genome evolution in two generalist and specialist microsporidian pathogens of mosquitoes.
C. A. Desjardins, Sanscrainte, N. D. , Goldberg, J. M. , Heiman, D. , Young, S. , Zeng, Q. , Madhani, H. D. , Becnel, J. J. , and Cuomo, C. A. , “Contrasting host-pathogen interactions and genome evolution in two generalist and specialist microsporidian pathogens of mosquitoes.”, Nat Commun, vol. 6, p. 7121, 2015.
Degeneration of the nonrecombining regions in the mating-type chromosomes of the anther-smut fungi.
E. Fontanillas, Hood, M. E. , Badouin, H. , Petit, E. , Barbe, V. , Gouzy, J. , de Vienne, D. M. , Aguileta, G. , Poulain, J. , Wincker, P. , Chen, Z. , San Toh, S. , Cuomo, C. A. , Perlin, M. H. , Gladieux, P. , and Giraud, T. , “Degeneration of the nonrecombining regions in the mating-type chromosomes of the anther-smut fungi.”, Mol Biol Evol, vol. 32, no. 4, pp. 928-43, 2015.
Finding a Missing Gene: EFG1 Regulates Morphogenesis in Candida tropicalis.
E. Mancera, Porman, A. M. , Cuomo, C. A. , Bennett, R. J. , and Johnson, A. D. , “Finding a Missing Gene: EFG1 Regulates Morphogenesis in Candida tropicalis.”, G3 (Bethesda), vol. 5, no. 5, pp. 849-56, 2015.
Genetic and phenotypic intra-species variation in Candida albicans.
M. P. Hirakawa, Martinez, D. A. , Sakthikumar, S. , Anderson, M. Z. , Berlin, A. , Gujja, S. , Zeng, Q. , Zisson, E. , Wang, J. M. , Greenberg, J. M. , Berman, J. , Bennett, R. J. , and Cuomo, C. A. , “Genetic and phenotypic intra-species variation in Candida albicans.”, Genome Res, vol. 25, no. 3, pp. 413-25, 2015.
Draft Genome Sequence of the Cellulolytic Fungus Chaetomium globosum.
C. A. Cuomo, Untereiner, W. A. , Ma, L. - J. , Grabherr, M. , and Birren, B. W. , “Draft Genome Sequence of the Cellulolytic Fungus Chaetomium globosum.”, Genome Announc, vol. 3, no. 1, 2015.
The evolution of drug resistance in clinical isolates of Candida albicans.
C. B. Ford, Funt, J. M. , Abbey, D. , Issi, L. , Guiducci, C. , Martinez, D. A. , Delorey, T. , Li, B. Yu, White, T. C. , Cuomo, C. , Rao, R. P. , Berman, J. , Thompson, D. A. , and Regev, A. , “The evolution of drug resistance in clinical isolates of Candida albicans.”, Elife, vol. 4, p. e00662, 2015.
50 Years of Emmonsia Disease in Humans: The Dramatic Emergence of a Cluster of Novel Fungal Pathogens.
I. S. Schwartz, Kenyon, C. , Feng, P. , Govender, N. P. , Dukik, K. , Sigler, L. , Jiang, Y. , J Stielow, B. , Muñoz, J. F. , Cuomo, C. A. , Botha, A. , Stchigel, A. M. , and G de Hoog, S. , “50 Years of Emmonsia Disease in Humans: The Dramatic Emergence of a Cluster of Novel Fungal Pathogens.”, PLoS Pathog, vol. 11, no. 11, p. e1005198, 2015.
Genome update of the dimorphic human pathogenic fungi causing paracoccidioidomycosis.
J. F. Muñoz, Gallo, J. E. , Misas, E. , Priest, M. , Imamovic, A. , Young, S. , Zeng, Q. , Clay, O. K. , McEwen, J. G. , and Cuomo, C. A. , “Genome update of the dimorphic human pathogenic fungi causing paracoccidioidomycosis.”, PLoS Negl Trop Dis, vol. 8, no. 12, p. e3348, 2014.
Genome Sequence of the Microsporidian Species Nematocida sp1 Strain ERTm6 (ATCC PRA-372).
M. A. Bakowski, Priest, M. , Young, S. , Cuomo, C. A. , and Troemel, E. R. , “Genome Sequence of the Microsporidian Species Nematocida sp1 Strain ERTm6 (ATCC PRA-372).”, Genome Announc, vol. 2, no. 5, 2014.
Fungi on the skin: dermatophytes and Malassezia.
T. C. White, Findley, K. , Dawson, T. L. , Scheynius, A. , Boekhout, T. , Cuomo, C. A. , Xu, J. , and Saunders, C. W. , “Fungi on the skin: dermatophytes and Malassezia.”, Cold Spring Harb Perspect Med, vol. 4, no. 8, 2014.
Highly recombinant VGII Cryptococcus gattii population develops clonal outbreak clusters through both sexual macroevolution and asexual microevolution.
B. R Billmyre, Croll, D. , Li, W. , Mieczkowski, P. , Carter, D. A. , Cuomo, C. A. , Kronstad, J. W. , and Heitman, J. , “Highly recombinant VGII Cryptococcus gattii population develops clonal outbreak clusters through both sexual macroevolution and asexual microevolution.”, MBio, vol. 5, no. 4, pp. e01494-14, 2014.
Analysis of a food-borne fungal pathogen outbreak: virulence and genome of a Mucor circinelloides isolate from yogurt.
S. Chan Lee, R Billmyre, B. , Li, A. , Carson, S. , Sykes, S. M. , Huh, E. Young, Mieczkowski, P. , Ko, D. C. , Cuomo, C. A. , and Heitman, J. , “Analysis of a food-borne fungal pathogen outbreak: virulence and genome of a Mucor circinelloides isolate from yogurt.”, MBio, vol. 5, no. 4, pp. e01390-14, 2014.
Ubiquitin-mediated response to microsporidia and virus infection in C. elegans.
M. A. Bakowski, Desjardins, C. A. , Smelkinson, M. G. , Dunbar, T. L. , Dunbar, T. A. , Lopez-Moyado, I. F. , Rifkin, S. A. , Cuomo, C. A. , and Troemel, E. R. , “Ubiquitin-mediated response to microsporidia and virus infection in C. elegans.”, PLoS Pathog, vol. 10, no. 6, p. e1004200, 2014.
Genome Sequence of the Pathogenic Fungus Sporothrix schenckii (ATCC 58251).
C. A. Cuomo, Del Valle, N. Rodriguez-, Perez-Sanchez, L. , Abouelleil, A. , Goldberg, J. , Young, S. , Zeng, Q. , and Birren, B. W. , “Genome Sequence of the Pathogenic Fungus Sporothrix schenckii (ATCC 58251).”, Genome Announc, vol. 2, no. 3, 2014.
Comparative genomic and transcriptomic analysis of wangiella dermatitidis, a major cause of phaeohyphomycosis and a model black yeast human pathogen.
Z. Chen, Martinez, D. A. , Gujja, S. , Sykes, S. M. , Zeng, Q. , Szaniszlo, P. J. , Wang, Z. , and Cuomo, C. A. , “Comparative genomic and transcriptomic analysis of wangiella dermatitidis, a major cause of phaeohyphomycosis and a model black yeast human pathogen.”, G3 (Bethesda), vol. 4, no. 4, pp. 561-78, 2014.
Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.
G. Janbon, Ormerod, K. L. , Paulet, D. , Byrnes, E. J. , Yadav, V. , Chatterjee, G. , Mullapudi, N. , Hon, C. - C. , R Billmyre, B. , Brunel, F. , Bahn, Y. - S. , Chen, W. , Chen, Y. , Chow, E. W. L. , Coppée, J. - Y. , Floyd-Averette, A. , Gaillardin, C. , Gerik, K. J. , Goldberg, J. , Gonzalez-Hilarion, S. , Gujja, S. , Hamlin, J. L. , Hsueh, Y. - P. , Ianiri, G. , Jones, S. , Kodira, C. D. , Kozubowski, L. , Lam, W. , Marra, M. , Mesner, L. D. , Mieczkowski, P. A. , Moyrand, F. , Nielsen, K. , Proux, C. , Rossignol, T. , Schein, J. E. , Sun, S. , Wollschlaeger, C. , Wood, I. A. , Zeng, Q. , Neuvéglise, C. , Newlon, C. S. , Perfect, J. R. , Lodge, J. K. , Idnurm, A. , Stajich, J. E. , Kronstad, J. W. , Sanyal, K. , Heitman, J. , Fraser, J. A. , Cuomo, C. A. , and Dietrich, F. S. , “Analysis of the genome and transcriptome of Cryptococcus neoformans var. grubii reveals complex RNA expression and microevolution leading to virulence attenuation.”, PLoS Genet, vol. 10, no. 4, p. e1004261, 2014.
Using transcription of six Puccinia triticina races to identify the effective secretome during infection of wheat.
M. Bruce, Neugebauer, K. A. , Joly, D. L. , Migeon, P. , Cuomo, C. A. , Wang, S. , Akhunov, E. , Bakkeren, G. , Kolmer, J. A. , and Fellers, J. P. , “Using transcription of six Puccinia triticina races to identify the effective secretome during infection of wheat.”, Front Plant Sci, vol. 4, p. 520, 2014.
Comparative genomics of Australian isolates of the wheat stem rust pathogen Puccinia graminis f. sp. tritici reveals extensive polymorphism in candidate effector genes.
N. M. Upadhyaya, Garnica, D. P. , Karaoglu, H. , Sperschneider, J. , Nemri, A. , Xu, B. , Mago, R. , Cuomo, C. A. , Rathjen, J. P. , Park, R. F. , Ellis, J. G. , and Dodds, P. N. , “Comparative genomics of Australian isolates of the wheat stem rust pathogen Puccinia graminis f. sp. tritici reveals extensive polymorphism in candidate effector genes.”, Front Plant Sci, vol. 5, p. 759, 2014.
Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement.
B. J. Walker, Abeel, T. , Shea, T. , Priest, M. , Abouelliel, A. , Sakthikumar, S. , Cuomo, C. A. , Zeng, Q. , Wortman, J. , Young, S. K. , and Earl, A. M. , “Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement.”, PLoS One, vol. 9, no. 11, p. e112963, 2014.
Isolation of Blastomyces dermatitidis yeast from lung tissue during murine infection for in vivo transcriptional profiling.
A. J. Marty, Wüthrich, M. , Carmen, J. C. , Sullivan, T. D. , Klein, B. S. , Cuomo, C. A. , and Gauthier, G. M. , “Isolation of Blastomyces dermatitidis yeast from lung tissue during murine infection for in vivo transcriptional profiling.”, Fungal Genet Biol, vol. 56, pp. 1-8, 2013.
One fungus, one name: defining the genus Fusarium in a scientifically robust way that preserves longstanding use.
D. M. Geiser, Aoki, T. , Bacon, C. W. , Baker, S. E. , Bhattacharyya, M. K. , Brandt, M. E. , Brown, D. W. , Burgess, L. W. , Chulze, S. , Coleman, J. J. , Correll, J. C. , Covert, S. F. , Crous, P. W. , Cuomo, C. A. , G de Hoog, S. , Di Pietro, A. , Elmer, W. H. , Epstein, L. , Frandsen, R. J. N. , Freeman, S. , Gagkaeva, T. , Glenn, A. E. , Gordon, T. R. , Gregory, N. F. , Hammond-Kosack, K. E. , Hanson, L. E. , Jímenez-Gasco, M. Del Mar, Kang, S. , H Kistler, C. , Kuldau, G. A. , Leslie, J. F. , Logrieco, A. , Lu, G. , Lysøe, E. , Ma, L. - J. , McCormick, S. P. , Migheli, Q. , Moretti, A. , Munaut, F. , O'donnell, K. , Pfenning, L. , Ploetz, R. C. , Proctor, R. H. , Rehner, S. A. , Robert, V. A. R. G. , Rooney, A. P. , Bin Salleh, B. , Scandiani, M. Mercedes, Scauflaire, J. , Short, D. P. G. , Steenkamp, E. , Suga, H. , Summerell, B. A. , Sutton, D. A. , Thrane, U. , Trail, F. , Van Diepeningen, A. , Vanetten, H. D. , Viljoen, A. , Waalwijk, C. , Ward, T. J. , Wingfield, M. J. , Xu, J. - R. , Yang, X. - B. , Yli-Mattila, T. , and Zhang, N. , “One fungus, one name: defining the genus Fusarium in a scientifically robust way that preserves longstanding use.”, Phytopathology, vol. 103, no. 5, pp. 400-8, 2013.
Sequencing and characterization of the complete mitochondrial genomes of three Pneumocystis species provide new insights into divergence between human and rodent Pneumocystis.
L. Ma, Huang, D. - W. , Cuomo, C. A. , Sykes, S. , Fantoni, G. , Das, B. , Sherman, B. T. , Yang, J. , Huber, C. , Xia, Y. , Davey, E. , Kutty, G. , Bishop, L. , Sassi, M. , Lempicki, R. A. , and Kovacs, J. A. , “Sequencing and characterization of the complete mitochondrial genomes of three Pneumocystis species provide new insights into divergence between human and rodent Pneumocystis.”, FASEB J, vol. 27, no. 5, pp. 1962-72, 2013.
Complete genome sequences from three genetically distinct strains reveal high intraspecies genetic diversity in the microsporidian Encephalitozoon cuniculi.
J. - F. Pombert, Xu, J. , Smith, D. R. , Heiman, D. , Young, S. , Cuomo, C. A. , Weiss, L. M. , and Keeling, P. J. , “Complete genome sequences from three genetically distinct strains reveal high intraspecies genetic diversity in the microsporidian Encephalitozoon cuniculi.”, Eukaryot Cell, vol. 12, no. 4, pp. 503-11, 2013.
Conserved loci of leaf and stem rust fungi of wheat share synteny interrupted by lineage-specific influx of repeat elements.
J. P. Fellers, Soltani, B. M. , Bruce, M. , Linning, R. , Cuomo, C. A. , Szabo, L. J. , and Bakkeren, G. , “Conserved loci of leaf and stem rust fungi of wheat share synteny interrupted by lineage-specific influx of repeat elements.”, BMC Genomics, vol. 14, p. 60, 2013.
Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis.
W. Li, Sullivan, T. D. , Walton, E. , Averette, A. Floyd, Sakthikumar, S. , Cuomo, C. A. , Klein, B. S. , and Heitman, J. , “Identification of the mating-type (MAT) locus that controls sexual reproduction of Blastomyces dermatitidis.”, Eukaryot Cell, vol. 12, no. 1, pp. 109-17, 2013.
Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth.
C. A. Cuomo, Desjardins, C. A. , Bakowski, M. A. , Goldberg, J. , Ma, A. T. , Becnel, J. J. , Didier, E. S. , Fan, L. , Heiman, D. I. , Levin, J. Z. , Young, S. , Zeng, Q. , and Troemel, E. R. , “Microsporidian genome analysis reveals evolutionary strategies for obligate intracellular growth.”, Genome Res, vol. 22, no. 12, pp. 2478-88, 2012.
Linkage to the mating-type locus across the genus Microbotryum: insights into nonrecombining chromosomes.
E. Petit, Giraud, T. , de Vienne, D. M. , Coelho, M. A. , Aguileta, G. , Amselem, J. , Kreplak, J. , Poulain, J. , Gavory, F. , Wincker, P. , Young, S. K. , Cuomo, C. , Perlin, M. H. , and Hood, M. E. , “Linkage to the mating-type locus across the genus Microbotryum: insights into nonrecombining chromosomes.”, Evolution, vol. 66, no. 11, pp. 3519-33, 2012.
Novel, panzootic and hybrid genotypes of amphibian chytridiomycosis associated with the bullfrog trade.
L. M. Schloegel, Toledo, L. Felipe, Longcore, J. E. , Greenspan, S. E. , Vieira, C. Augusto, Lee, M. , Zhao, S. , Wangen, C. , Ferreira, C. Maris, Hipolito, M. , Davies, A. J. , Cuomo, C. A. , Daszak, P. , and James, T. Y. , “Novel, panzootic and hybrid genotypes of amphibian chytridiomycosis associated with the bullfrog trade.”, Mol Ecol, vol. 21, no. 21, pp. 5162-77, 2012.
Adaptation of the black yeast Wangiella dermatitidis to ionizing radiation: molecular and cellular mechanisms.
K. L. Robertson, Mostaghim, A. , Cuomo, C. A. , Soto, C. M. , Lebedev, N. , Bailey, R. F. , and Wang, Z. , “Adaptation of the black yeast Wangiella dermatitidis to ionizing radiation: molecular and cellular mechanisms.”, PLoS One, vol. 7, no. 11, p. e48674, 2012.
Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection.
D. A. Martinez, Oliver, B. G. , Gräser, Y. , Goldberg, J. M. , Li, W. , Martinez-Rossi, N. M. , Monod, M. , Shelest, E. , Barton, R. C. , Birch, E. , Brakhage, A. A. , Chen, Z. , Gurr, S. J. , Heiman, D. , Heitman, J. , Kosti, I. , Rossi, A. , Saif, S. , Samalova, M. , Saunders, C. W. , Shea, T. , Summerbell, R. C. , Xu, J. , Young, S. , Zeng, Q. , Birren, B. W. , Cuomo, C. A. , and White, T. C. , “Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection.”, MBio, vol. 3, no. 5, pp. e00259-12, 2012.
Approaches to Fungal Genome Annotation.
B. J. Haas, Zeng, Q. , Pearson, M. D. , Cuomo, C. A. , and Wortman, J. R. , “Approaches to Fungal Genome Annotation.”, Mycology, vol. 2, no. 3, pp. 118-141, 2011.
Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis.
C. A. Desjardins, Champion, M. D. , Holder, J. W. , Muszewska, A. , Goldberg, J. , Bailão, A. M. , Brigido, M. Macedo, Ferreira, M. Eliana da, Garcia, A. Maria, Grynberg, M. , Gujja, S. , Heiman, D. I. , Henn, M. R. , Kodira, C. D. , León-Narváez, H. , Longo, L. V. G. , Ma, L. - J. , Malavazi, I. , Matsuo, A. L. , Morais, F. V. , Pereira, M. , Rodríguez-Brito, S. , Sakthikumar, S. , Salem-Izacc, S. M. , Sykes, S. M. , Teixeira, M. Melo, Vallejo, M. C. , Walter, M. Emília Ma, Yandava, C. , Young, S. , Zeng, Q. , Zucker, J. , Felipe, M. Sueli, Goldman, G. H. , Haas, B. J. , McEwen, J. G. , Nino-Vega, G. , Puccia, R. , San-Blas, G. , Soares, C. Maria de A. , Birren, B. W. , and Cuomo, C. A. , “Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis.”, PLoS Genet, vol. 7, no. 10, p. e1002345, 2011.
Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea.
J. Amselem, Cuomo, C. A. , van Kan, J. A. L. , Viaud, M. , Benito, E. P. , Couloux, A. , Coutinho, P. M. , de Vries, R. P. , Dyer, P. S. , Fillinger, S. , Fournier, E. , Gout, L. , Hahn, M. , Kohn, L. , Lapalu, N. , Plummer, K. M. , Pradier, J. - M. , Quévillon, E. , Sharon, A. , Simon, A. , Have, Aten, Tudzynski, B. , Tudzynski, P. , Wincker, P. , Andrew, M. , Anthouard, V. , Beever, R. E. , Beffa, R. , Benoit, I. , Bouzid, O. , Brault, B. , Chen, Z. , Choquer, M. , Collémare, J. , Cotton, P. , Danchin, E. G. , Da Silva, C. , Gautier, A. , Giraud, C. , Giraud, T. , Gonzalez, C. , Grossetete, S. , Güldener, U. , Henrissat, B. , Howlett, B. J. , Kodira, C. , Kretschmer, M. , Lappartient, A. , Leroch, M. , Levis, C. , Mauceli, E. , Neuvéglise, C. , Oeser, B. , Pearson, M. , Poulain, J. , Poussereau, N. , Quesneville, H. , Rascle, C. , Schumacher, J. , Segurens, B. , Sexton, A. , Silva, E. , Sirven, C. , Soanes, D. M. , Talbot, N. J. , Templeton, M. , Yandava, C. , Yarden, O. , Zeng, Q. , Rollins, J. A. , Lebrun, M. - H. , and Dickman, M. , “Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea.”, PLoS Genet, vol. 7, no. 8, p. e1002230, 2011.
Comparative genomics yields insights into niche adaptation of plant vascular wilt pathogens.
S. J. Klosterman, Subbarao, K. V. , Kang, S. , Veronese, P. , Gold, S. E. , Thomma, B. P. H. J. , Chen, Z. , Henrissat, B. , Lee, Y. - H. , Park, J. , Garcia-Pedrajas, M. D. , Barbara, D. J. , Anchieta, A. , de Jonge, R. , Santhanam, P. , Maruthachalam, K. , Atallah, Z. , Amyotte, S. G. , Paz, Z. , Inderbitzin, P. , Hayes, R. J. , Heiman, D. I. , Young, S. , Zeng, Q. , Engels, R. , Galagan, J. , Cuomo, C. A. , Dobinson, K. F. , and Ma, L. - J. , “Comparative genomics yields insights into niche adaptation of plant vascular wilt pathogens.”, PLoS Pathog, vol. 7, no. 7, p. e1002137, 2011.
Obligate biotrophy features unraveled by the genomic analysis of rust fungi.
S. Duplessis, Cuomo, C. A. , Lin, Y. - C. , Aerts, A. , Tisserant, E. , Veneault-Fourrey, C. , Joly, D. L. , Hacquard, S. , Amselem, J. , Cantarel, B. L. , Chiu, R. , Coutinho, P. M. , Feau, N. , Field, M. , Frey, P. , Gelhaye, E. , Goldberg, J. , Grabherr, M. G. , Kodira, C. D. , Kohler, A. , Kües, U. , Lindquist, E. A. , Lucas, S. M. , Mago, R. , Mauceli, E. , Morin, E. , Murat, C. , Pangilinan, J. L. , Park, R. , Pearson, M. , Quesneville, H. , Rouhier, N. , Sakthikumar, S. , Salamov, A. A. , Schmutz, J. , Selles, B. , Shapiro, H. , Tanguay, P. , Tuskan, G. A. , Henrissat, B. , Van de Peer, Y. , Rouzé, P. , Ellis, J. G. , Dodds, P. N. , Schein, J. E. , Zhong, S. , Hamelin, R. C. , Grigoriev, I. V. , Szabo, L. J. , and Martin, F. , “Obligate biotrophy features unraveled by the genomic analysis of rust fungi.”, Proc Natl Acad Sci U S A, vol. 108, no. 22, pp. 9166-71, 2011.
Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts.
C. A. D'Souza, Kronstad, J. W. , Taylor, G. , Warren, R. , Yuen, M. , Hu, G. , Jung, W. H. , Sham, A. , Kidd, S. E. , Tangen, K. , Lee, N. , Zeilmaker, T. , Sawkins, J. , McVicker, G. , Shah, S. , Gnerre, S. , Griggs, A. , Zeng, Q. , Bartlett, K. , Li, W. , Wang, X. , Heitman, J. , Stajich, J. E. , Fraser, J. A. , Meyer, W. , Carter, D. , Schein, J. , Krzywinski, M. , Kwon-Chung, K. J. , Varma, A. , Wang, J. , Brunham, R. , Fyfe, M. , Ouellette, B. F. F. , Siddiqui, A. , Marra, M. , Jones, S. , Holt, R. , Birren, B. W. , Galagan, J. E. , and Cuomo, C. A. , “Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts.”, MBio, vol. 2, no. 1, pp. e00342-10, 2011.
SREB, a GATA transcription factor that directs disparate fates in Blastomyces dermatitidis including morphogenesis and siderophore biosynthesis.
G. M. Gauthier, Sullivan, T. D. , Gallardo, S. S. , T Brandhorst, T. , Wymelenberg, A. J. Vanden, Cuomo, C. A. , Suen, G. , Currie, C. R. , and Klein, B. S. , “SREB, a GATA transcription factor that directs disparate fates in Blastomyces dermatitidis including morphogenesis and siderophore biosynthesis.”, PLoS Pathog, vol. 6, no. 4, p. e1000846, 2010.
Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium.
L. - J. Ma, H van der Does, C. , Borkovich, K. A. , Coleman, J. J. , Daboussi, M. - J. , Di Pietro, A. , Dufresne, M. , Freitag, M. , Grabherr, M. , Henrissat, B. , Houterman, P. M. , Kang, S. , Shim, W. - B. , Woloshuk, C. , Xie, X. , Xu, J. - R. , Antoniw, J. , Baker, S. E. , Bluhm, B. H. , Breakspear, A. , Brown, D. W. , Butchko, R. A. E. , Chapman, S. , Coulson, R. , Coutinho, P. M. , Danchin, E. G. J. , Diener, A. , Gale, L. R. , Gardiner, D. M. , Goff, S. , Hammond-Kosack, K. E. , Hilburn, K. , Hua-Van, A. , Jonkers, W. , Kazan, K. , Kodira, C. D. , Koehrsen, M. , Kumar, L. , Lee, Y. - H. , Li, L. , Manners, J. M. , Miranda-Saavedra, D. , Mukherjee, M. , Park, G. , Park, J. , Park, S. - Y. , Proctor, R. H. , Regev, A. , M Ruiz-Roldan, C. , Sain, D. , Sakthikumar, S. , Sykes, S. , Schwartz, D. C. , B Turgeon, G. , Wapinski, I. , Yoder, O. , Young, S. , Zeng, Q. , Zhou, S. , Galagan, J. , Cuomo, C. A. , H Kistler, C. , and Rep, M. , “Comparative genomics reveals mobile pathogenicity chromosomes in Fusarium.”, Nature, vol. 464, no. 7287, pp. 367-73, 2010.
The fungal genome initiative and lessons learned from genome sequencing.
C. A. Cuomo and Birren, B. W. , “The fungal genome initiative and lessons learned from genome sequencing.”, Methods Enzymol, vol. 470, pp. 833-55, 2010.
Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication.
L. - J. Ma, Ibrahim, A. S. , Skory, C. , Grabherr, M. G. , Burger, G. , Butler, M. , Elias, M. , Idnurm, A. , B Lang, F. , Sone, T. , Abe, A. , Calvo, S. E. , Corrochano, L. M. , Engels, R. , Fu, J. , Hansberg, W. , Kim, J. - M. , Kodira, C. D. , Koehrsen, M. J. , Liu, B. , Miranda-Saavedra, D. , O'Leary, S. , Ortiz-Castellanos, L. , Poulter, R. , Rodriguez-Romero, J. , Ruiz-Herrera, J. , Shen, Y. - Q. , Zeng, Q. , Galagan, J. , Birren, B. W. , Cuomo, C. A. , and Wickes, B. L. , “Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication.”, PLoS Genet, vol. 5, no. 7, p. e1000549, 2009.
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
G. Butler, Rasmussen, M. D. , Lin, M. F. , Santos, M. A. S. , Sakthikumar, S. , Munro, C. A. , Rheinbay, E. , Grabherr, M. , Forche, A. , Reedy, J. L. , Agrafioti, I. , Arnaud, M. B. , Bates, S. , Brown, A. J. P. , Brunke, S. , Costanzo, M. C. , Fitzpatrick, D. A. , de Groot, P. W. J. , Harris, D. , Hoyer, L. L. , Hube, B. , Klis, F. M. , Kodira, C. , Lennard, N. , Logue, M. E. , Martin, R. , Neiman, A. M. , Nikolaou, E. , Quail, M. A. , Quinn, J. , Santos, M. C. , Schmitzberger, F. F. , Sherlock, G. , Shah, P. , Silverstein, K. A. T. , Skrzypek, M. S. , Soll, D. , Staggs, R. , Stansfield, I. , Stumpf, M. P. H. , Sudbery, P. E. , Srikantha, T. , Zeng, Q. , Berman, J. , Berriman, M. , Heitman, J. , Gow, N. A. R. , Lorenz, M. C. , Birren, B. W. , Kellis, M. , and Cuomo, C. A. , “Evolution of pathogenicity and sexual reproduction in eight Candida genomes.”, Nature, vol. 459, no. 7247, pp. 657-62, 2009.
The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization.
C. A. Cuomo, Güldener, U. , Xu, J. - R. , Trail, F. , B Turgeon, G. , Di Pietro, A. , Walton, J. D. , Ma, L. - J. , Baker, S. E. , Rep, M. , Adam, G. , Antoniw, J. , Baldwin, T. , Calvo, S. , Chang, Y. - L. , DeCaprio, D. , Gale, L. R. , Gnerre, S. , Goswami, R. S. , Hammond-Kosack, K. , Harris, L. J. , Hilburn, K. , Kennell, J. C. , Kroken, S. , Magnuson, J. K. , Mannhaupt, G. , Mauceli, E. , Mewes, H. - W. , Mitterbauer, R. , Muehlbauer, G. , Münsterkötter, M. , Nelson, D. , O'donnell, K. , Ouellet, T. , Qi, W. , Quesneville, H. , M Roncero, I. G. , Seong, K. - Y. , Tetko, I. V. , Urban, M. , Waalwijk, C. , Ward, T. J. , Yao, J. , Birren, B. W. , and H Kistler, C. , “The Fusarium graminearum genome reveals a link between localized polymorphism and pathogen specialization.”, Science, vol. 317, no. 5843, pp. 1400-2, 2007.
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.
J. E. Galagan, Calvo, S. E. , Cuomo, C. , Ma, L. - J. , Wortman, J. R. , Batzoglou, S. , Lee, S. - I. , Baştürkmen, M. , Spevak, C. C. , Clutterbuck, J. , Kapitonov, V. , Jurka, J. , Scazzocchio, C. , Farman, M. , Butler, J. , Purcell, S. , Harris, S. , Braus, G. H. , Draht, O. , Busch, S. , D'Enfert, C. , Bouchier, C. , Goldman, G. H. , Bell-Pedersen, D. , Griffiths-Jones, S. , Doonan, J. H. , Yu, J. , Vienken, K. , Pain, A. , Freitag, M. , Selker, E. U. , Archer, D. B. , Peñalva, M. A. , Oakley, B. R. , Momany, M. , Tanaka, T. , Kumagai, T. , Asai, K. , Machida, M. , Nierman, W. C. , Denning, D. W. , Caddick, M. , Hynes, M. , Paoletti, M. , Fischer, R. , Miller, B. , Dyer, P. , Sachs, M. S. , Osmani, S. A. , and Birren, B. W. , “Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.”, Nature, vol. 438, no. 7071, pp. 1105-15, 2005.