Bacterial Genomics Group

R. A. Bronson, Gupta, C., Manson, A. L., Nguyen, J. A., Bahadirli-Talbott, A., Parrish, N. M., Earl, A. M., and Cohen, K. A., “Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance.”, Nat Commun, vol. 12, no. 1, p. 5145, 2021.DOIGoogle ScholarPubMed

P. Ma, He, L. L., Pironti, A., Laibinis, H. H., Ernst, C. M., Manson, A. L., Bhattacharyya, R. P., Earl, A. M., Livny, J., and Hung, D. T., “Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics.”, Elife, vol. 10, 2021.DOIGoogle ScholarPubMed

A. J. Lopatkin, Bening, S. C., Manson, A. L., Stokes, J. M., Kohanski, M. A., Badran, A. H., Earl, A. M., Cheney, N. J., Yang, J. H., and Collins, J. J., “Clinically relevant mutations in core metabolic genes confer antibiotic resistance.”, Science, vol. 371, no. 6531, 2021.DOIGoogle ScholarPubMed

T. J. Straub, Chou, W. -C., Manson, A. L., Schreiber, H. L., Walker, B. J., Desjardins, C. A., Chapman, S. B., Kaspar, K. L., Kahsai, O. J., Traylor, E., Dodson, K. W., Hullar, M. A. J., Hultgren, S. J., Khoo, C., and Earl, A. M., “Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections.”, BMC Microbiol, vol. 21, no. 1, p. 53, 2021.DOIGoogle ScholarPubMed

C. J. Worby, Earl, A. M., Turbett, S. E., Becker, M., Rao, S. R., Oliver, E., Walker, A. T., Walters, M., Kelly, P., Leung, D. T., Knouse, M., Hagmann, S. H. F., Ryan, E. T., and LaRocque, R. C., “Acquisition and Long-term Carriage of Multidrug-Resistant Organisms in US International Travelers.”, Open Forum Infect Dis, vol. 7, no. 12, p. ofaa543, 2020.DOIGoogle ScholarPubMed

M. S. Gilmore, Salamzade, R., Selleck, E., Bryan, N., Mello, S. S., Manson, A. L., and Earl, A. M., “Genes Contributing to the Unique Biology and Intrinsic Antibiotic Resistance of Enterococcus faecalis.”, mBio, vol. 11, no. 6, 2020.DOIGoogle ScholarPubMed

K. A. Cohen, Stott, K. E., Munsamy, V., Manson, A. L., Earl, A. M., and Pym, A. S., “Evidence for Expanding the Role of Streptomycin in the Management of Drug-Resistant Mycobacterium tuberculosis.”, Antimicrob Agents Chemother, vol. 64, no. 9, 2020.DOIGoogle ScholarPubMed

G. P. Donaldson, Chou, W. -C., Manson, A. L., Rogov, P., Abeel, T., Bochicchio, J., Ciulla, D., Melnikov, A., Ernst, P. B., Chu, H., Giannoukos, G., Earl, A. M., and Mazmanian, S. K., “Spatially distinct physiology of Bacteroides fragilis within the proximal colon of gnotobiotic mice.”, Nat Microbiol, vol. 5, no. 5, pp. 746-756, 2020.DOIGoogle ScholarPubMed

C. M. Ernst, Braxton, J. R., Rodriguez-Osorio, C. A., Zagieboylo, A. P., Li, L., Pironti, A., Manson, A. L., Nair, A. V., Benson, M., Cummins, K., Clatworthy, A. E., Earl, A. M., Cosimi, L. A., and Hung, D. T., “Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae.”, Nat Med, 2020.DOIGoogle ScholarPubMed

G. Mellon, Turbett, S. E., Worby, C., Oliver, E., Walker, T., Walters, M., Kelly, P., Leung, D. T., Knouse, M., Hagmann, S., Earl, A., Ryan, E. T., and LaRocque, R. C., “Acquisition of Antibiotic-Resistant Bacteria by U.S. International Travelers.”, N Engl J Med, vol. 382, no. 14, pp. 1372-1374, 2020.DOIGoogle ScholarPubMed