Diabetes

Loss of Mtarc1 Protects Against Steatotic Liver Disease in Mice.

Yin X, Bickerton C, MacDonald B, et al. Loss of Mtarc1 Protects Against Steatotic Liver Disease in Mice. Liver international : official journal of the International Association for the Study of the Liver. 2026;46(2):e70507. doi:10.1111/liv.70507DOI Google Scholar PubMed

Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic Score.

Deutsch AJ, Bell AS, Michalek DA, et al. Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic Score. Diabetes. 2025. doi:10.2337/db25-0772DOI Google Scholar PubMed

Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms.

Rusu V, Hoch E, Mercader JM, et al. Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms. Cell. 2017;170(1):199-212.e20. doi:10.1016/j.cell.2017.06.011DOI Google Scholar PubMed

Type 2 diabetes: genetic data sharing to advance complex disease research.

Flannick J, Florez JC. Type 2 diabetes: genetic data sharing to advance complex disease research. Nat Rev Genet. 2016;17(9):535-49. doi:10.1038/nrg.2016.56DOI Google Scholar PubMed

The genetic architecture of type 2 diabetes.

Fuchsberger C, Flannick J, Teslovich TM, et al. The genetic architecture of type 2 diabetes. Nature. 2016;536(7614):41-7. doi:10.1038/nature18642DOI Google Scholar PubMed

Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology.

Lane JM, Chang AM, Bjonnes AC, et al. Impact of Common Diabetes Risk Variant in MTNR1B on Sleep, Circadian, and Melatonin Physiology. Diabetes. 2016;65(6):1741-51. doi:10.2337/db15-0999DOI Google Scholar PubMed

Inhibition of DYRK1A Stimulates Human β-Cell Proliferation.

Dirice E, Walpita D, Vetere A, et al. Inhibition of DYRK1A Stimulates Human β-Cell Proliferation. Diabetes. 2016;65(6):1660-71. doi:10.2337/db15-1127DOI Google Scholar PubMed

Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants.

Hivert MF, Christophi CA, Franks PW, et al. Lifestyle and Metformin Ameliorate Insulin Sensitivity Independently of the Genetic Burden of Established Insulin Resistance Variants in Diabetes Prevention Program Participants. Diabetes. 2016;65(2):520-6. doi:10.2337/db15-0950DOI Google Scholar PubMed

Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis.

Kang S, Tsai LT, Zhou Y, et al. Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis. Nat Cell Biol. 2015;17(1):44-56. doi:10.1038/ncb3080DOI Google Scholar PubMed

The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes.

Walford GA, Colomo N, Todd JN, et al. The study to understand the genetics of the acute response to metformin and glipizide in humans (SUGAR-MGH): design of a pharmacogenetic resource for type 2 diabetes. PLoS One. 2015;10(3):e0121553. doi:10.1371/journal.pone.0121553DOI Google Scholar PubMed