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Hung Lab

Slater LH, Clatworthy AE, Hung DT. Bacterial toxins and small molecules elucidate endosomal trafficking. Trends Microbiol. 2014;22(2):53-5. doi:10.1016/j.tim.2013.12.002.
Grant SSchmidt, Kaufmann BB, Chand NS, Haseley N, Hung DT. Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals. Proc Natl Acad Sci U S A. 2012;109(30):12147-52. doi:10.1073/pnas.1203735109.
Barczak AK, Gomez JE, Kaufmann BB, et al. RNA signatures allow rapid identification of pathogens and antibiotic susceptibilities. Proc Natl Acad Sci U S A. 2012;109(16):6217-22. doi:10.1073/pnas.1119540109.
Chand NS, Lee JSee-Wai, Clatworthy AE, Golas AJ, Smith RS, Hung DT. The sensor kinase KinB regulates virulence in acute Pseudomonas aeruginosa infection. J Bacteriol. 2011;193(12):2989-99. doi:10.1128/JB.01546-10.
Clatworthy AE, Lee JSee-Wai, Leibman M, Kostun Z, Davidson AJ, Hung DT. Pseudomonas aeruginosa infection of zebrafish involves both host and pathogen determinants. Infect Immun. 2009;77(4):1293-303. doi:10.1128/IAI.01181-08.
Clatworthy AE, Pierson E, Hung DT. Targeting virulence: a new paradigm for antimicrobial therapy. Nat Chem Biol. 2007;3(9):541-8. doi:10.1038/nchembio.2007.24.
Hung DT, Rubin EJ. Chemical biology and bacteria: not simply a matter of life or death. Curr Opin Chem Biol. 2006;10(4):321-6. doi:10.1016/j.cbpa.2006.06.016.
Hung DT, Shakhnovich EA, Pierson E, Mekalanos JJ. Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization. Science. 2005;310(5748):670-4. doi:10.1126/science.1116739.