Stanley Center for Psychiatric Research

Meta-analysis of the brain transcriptomes of multiple genetic mouse models of schizophrenia highlights dysregulation in striatum and thalamus.

Mandell KAP, Simmons SK, Nadig A, et al. Meta-analysis of the brain transcriptomes of multiple genetic mouse models of schizophrenia highlights dysregulation in striatum and thalamus. Translational psychiatry. 2025;15(1):345. doi:10.1038/s41398-025-03563-5Google Scholar DOI PubMed

Tervi A, Ramste M, Abner E, et al. Genetic and functional analysis of Raynaud’s syndrome implicates loci in vasculature and immunity. Cell genomics. 2024:100630. doi:10.1016/j.xgen.2024.100630Google Scholar DOI PubMed

Ling E, Nemesh J, Goldman M, et al. A concerted neuron-astrocyte program declines in ageing and schizophrenia. Nature. 2024. doi:10.1038/s41586-024-07109-5Google Scholar DOI PubMed

Ma R, Conley SD, Kosicki M, et al. Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.11.20.24317557Google Scholar DOI PubMed

Zeng H, Huang J, Zhou H, et al. Integrative in situ mapping of single-cell transcriptional states and tissue histopathology in a mouse model of Alzheimer’s disease. Nature neuroscience. 2023. doi:10.1038/s41593-022-01251-xGoogle Scholar DOI PubMed

Farsi Z, Nicolella A, Simmons SK, et al. Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice. Neuron. 2023. doi:10.1016/j.neuron.2023.08.004Google Scholar DOI PubMed

Shi H, He Y, Zhou Y, et al. Spatial atlas of the mouse central nervous system at molecular resolution. Nature. 2023. doi:10.1038/s41586-023-06569-5Google Scholar DOI PubMed

Langlieb J, Sachdev NS, Balderrama KS, et al. The molecular cytoarchitecture of the adult mouse brain. Nature. 2023;624(7991):333-342. doi:10.1038/s41586-023-06818-7Google Scholar DOI PubMed

Krainc D, Martin WJ, Casey B, et al. Shifting the trajectory of therapeutic development for neurological and psychiatric disorders. Science translational medicine. 2023;15(720):eadg4775. doi:10.1126/scitranslmed.adg4775Google Scholar DOI PubMed

Huang Q, Chen AT, Chan KY, et al. Targeting AAV vectors to the central nervous system by engineering capsid-receptor interactions that enable crossing of the blood-brain barrier. PLoS biology. 2023;21(7):e3002112. doi:10.1371/journal.pbio.3002112Google Scholar DOI PubMed