Medical and Population Genetics Program

Kamineni M, Raghu V, Hua Z, et al. Machine learning-driven spleen imaging and genomics uncover a splenic connection to coronary artery disease. Science translational medicine. 2026;18(866):eaeh2517. doi:10.1126/scitranslmed.aeh2517Google ScholarPubMedDOI

Lee JH, Li Z, Soto JS, et al. Antigen presentation by CD40MHC-II astrocytes promotes CNS autoimmunity. Nature. 2026. doi:10.1038/s41586-026-10860-6Google ScholarPubMedDOI

Peyrot WJ, Panagiotaropoulou G, Loohuis LMO, et al. Distinguishing different psychiatric disorders using DDx-PRS. Nature genetics. 2026. doi:10.1038/s41588-026-02684-xGoogle ScholarPubMedDOI

Sugiarto NW, Gurajala S, Curtis M, et al. A population-scale transcriptional atlas of blood and tissue in lupus nephritis. Science translational medicine. 2026;18(863):eaec0512. doi:10.1126/scitranslmed.aec0512Google ScholarPubMedDOI

Orchard P, Blackwell TW, Kachuri L, et al. Cross-cohort analysis of expression and splicing quantitative trait loci in TOPMed. Science (New York, N.Y.). 2026;393(6808):eadx2989. doi:10.1126/science.adx2989Google ScholarPubMedDOI

Li H, Kamath T, Mazumder R, Lin X, O’Connor LJ. Improved heritability partitioning and enrichment analyses using summary statistics with graphREML. Nature genetics. 2026;58(7):1573-1582. doi:10.1038/s41588-026-02649-0Google ScholarPubMedDOI

Boltz TA, Chu BB, DeFelice M, et al. A blended genome and exome sequencing method captures genetic variation in an unbiased and cost-effective manner. Nature genetics. 2026. doi:10.1038/s41588-026-02669-wGoogle ScholarPubMedDOI

Zhou Z, Luquette LJ, Dong G, et al. Recurrent patterns of TOP1-mediated neuronal genomic damage shared by major neurodegenerative disorders. Cell. 2026. doi:10.1016/j.cell.2026.06.013Google ScholarPubMedDOIPubMed Central

Boone PM, Erdin S, Mohamed A, et al. Clinical, in vitro, and in vivo evidence of WAPL as a cohesinopathy-associated gene and phenotypic driver of 10q22.3q23.2 genomic disorder. American journal of human genetics. 2026. doi:10.1016/j.ajhg.2026.06.012Google ScholarPubMedDOI

Patterson N, Mushrif-Tripathy V, Devers Q, et al. Ancient genomes from Ladakh reveal 2800-year-old admixture between Tibetans and South Asians. Science advances. 2026;12(30):eaeb3636. doi:10.1126/sciadv.aeb3636Google ScholarPubMedDOIPubMed Central