Proteomics Platform

Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications.

Ctortecka C, Clark NM, Boyle B, et al. Automated single-cell proteomics providing sufficient proteome depth to study complex biology beyond cell type classifications. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.01.20.576369PubMed Google Scholar DOI

Molecular and cellular mechanisms of teneurin signaling in synaptic partner matching.

Xu C, Li Z, Lyu C, et al. Molecular and cellular mechanisms of teneurin signaling in synaptic partner matching. Cell. 2024. doi:10.1016/j.cell.2024.06.022PubMed Google Scholar DOI

Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease.

Zhu QM, Hsu YHH, Lassen FH, et al. Protein interaction networks in the vasculature prioritize genes and pathways underlying coronary artery disease. Communications biology. 2024;7(1):87. doi:10.1038/s42003-023-05705-1PubMed Google Scholar DOI

Directed evolution of the multicopper oxidase laccase for cell surface proximity labeling and electron microscopy.

Lee SY, Roh H, Gonzalez-Perez D, et al. Directed evolution of the multicopper oxidase laccase for cell surface proximity labeling and electron microscopy. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.10.29.620861PubMed Google Scholar DOI

Clinical Proteomics: A Promise Becoming Reality.

Gillette MA, Jimenez CR, Carr SA. Clinical Proteomics: A Promise Becoming Reality. Molecular & cellular proteomics : MCP. 2024;23(2):100688. doi:10.1016/j.mcpro.2023.100688PubMed Google Scholar DOI

An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing.

Waterbury AL, Kwok HS, Lee C, et al. An autoinhibitory switch of the LSD1 disordered region controls enhancer silencing. Molecular cell. 2024. doi:10.1016/j.molcel.2024.05.017PubMed Google Scholar DOI

High-quality peptide evidence for annotating non-canonical open reading frames as human proteins.

Deutsch EW, Kok LW, Mudge JM, et al. High-quality peptide evidence for annotating non-canonical open reading frames as human proteins. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.09.09.612016PubMed Google Scholar DOI

SHIFTR enables the unbiased identification of proteins bound to specific RNA regions in live cells.

Aydin J, Gabel A, Zielinski S, et al. SHIFTR enables the unbiased identification of proteins bound to specific RNA regions in live cells. Nucleic acids research. 2024. doi:10.1093/nar/gkae038PubMed Google Scholar DOI

Molecular basis of TMED9 oligomerization and entrapment of misfolded protein cargo in the early secretory pathway.

Xiao L, Pi X, Goss AC, et al. Molecular basis of TMED9 oligomerization and entrapment of misfolded protein cargo in the early secretory pathway. Science advances. 2024;10(38):eadp2221. doi:10.1126/sciadv.adp2221PubMed Google Scholar DOI

Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation.

Cieri N, Hookeri N, Stromhaug K, et al. Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation. Nature biotechnology. 2024. doi:10.1038/s41587-024-02348-3PubMed Google Scholar DOI