Proteomics Platform

Dynamic mapping of proteome trafficking within and between living cells by TransitID.

Xu W, Cheah J, Xu C, et al. Dynamic mapping of proteome trafficking within and between living cells by TransitID. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.02.07.527548Google Scholar DOI PubMed

Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells.

Lee SY, Cheah JS, Zhao B, et al. Engineered allostery in light-regulated LOV-Turbo enables precise spatiotemporal control of proximity labeling in living cells. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.09.531939Google Scholar DOI PubMed

Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry.

Phulphagar KM, Ctortecka C, Jacome ASV, et al. Sensitive, high-throughput HLA-I and HLA-II immunopeptidomics using parallel accumulation-serial fragmentation mass spectrometry. bioRxiv : the preprint server for biology. 2023. doi:10.1101/2023.03.10.532106Google Scholar DOI PubMed

Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Abelin J, Bergstrom E, Rivera K, et al. Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues. Nature communications. 2023;14(1):1851. doi:10.1038/s41467-023-37547-0Google Scholar DOI PubMed

LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma.

Sato S, Gillette M, de Santiago P, et al. LINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma. Scientific reports. 2023;13(1):1537. doi:10.1038/s41598-023-28840-5Google Scholar DOI PubMed

ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling.

Gentili M, Liu B, Papanastasiou M, et al. ESCRT-dependent STING degradation inhibits steady-state and cGAMP-induced signalling. Nature communications. 2023;14(1):611. doi:10.1038/s41467-023-36132-9Google Scholar DOI PubMed

A ubiquitination cascade regulating the integrated stress response and survival in carcinomas.

Cervia LD, Shibue T, Borah AA, et al. A ubiquitination cascade regulating the integrated stress response and survival in carcinomas. Cancer Discov. 2022. doi:10.1158/2159-8290.CD-22-1230Google Scholar DOI PubMed

HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses.

Weingarten-Gabbay S, Pearlman LR, Chen DY, et al. HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses. STAR Protoc. 2022;3(4):101910. doi:10.1016/j.xpro.2022.101910Google Scholar DOI PubMed

In situ cell-type-specific cell-surface proteomic profiling in mice.

Shuster A, Li J, Chon U, et al. In situ cell-type-specific cell-surface proteomic profiling in mice. Neuron. 2022;110(23):3882-3896.e9. doi:10.1016/j.neuron.2022.09.025Google Scholar DOI PubMed

CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.

Jutzi JS, Marneth AE, Jiménez-Santos MJ, et al. CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response. Leukemia. 2022. doi:10.1038/s41375-022-01781-0Google Scholar DOI PubMed