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Systems and Methods for MHC Class II Epitope Prediction

Application No.

PCT/US2018/039843

Broad Case No.

BI-10062

List of inventors -

Daniel Graham, Chengwei Luo, Ramnik Xavier

Abstract

A system and method for prediction of immunodominant epitopes is provided herein. MHCII peptidomics was used to discover complex bacterial epitopes and host antigen processing pathways. Novel insights into the features of antigenicity are leveraged to build an algorithm for prediction of immunodominant epitopes. Use of immunodominant epitopes is described.

Date PUBLISHED

  • 01/03/2019

Published Patent Application

  • WO2019/006022

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