Novel Delivery of Large Payloads

Application No.
PCT/US2018/027793
Broad Case No.
BI-10159
Inventors

Sourav Choudhury, Qiaobing Xu, Feng Zhang

Abstract

The disclosure includes non-naturally occurring or engineered CRISPR systems and proteins, associated with a delivery system comprising a virus component and a lipid component. The disclosure includes CRISPR proteins associated with capsid proteins, e.g., AAV VP!, VP2, and/or VP3, on the surface of or internal to the AAV, along with compositions, systems and complexes involving the AAV-CRISPR protein, nucleic acid molecules and vectors encoding the same, deliver}- systems, and uses therefor.

Date Published
Published Patent Application
WO2018/191750
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