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Neuronal Assay Method Involving Calcineurin

Application No.

PCT/IB2018/056171

Broad Case No.

BI-10145

List of inventors -

Jeffrey Cottrell, Ayan Ghoshal, Li Li, Yan-Ling Zhang

Abstract

This disclosure relates to methods of detecting and quantifying neuronal activation. This disclosure further relates to a particular phosphorylation of calcineurin A alpha (CNAa) at serine 469 (S469) of the amino acid sequence of the protein as a marker for neuronal activation, antibodies recognizing that phosphorylated form of CNAa, and uses of such antibodies, for example, in various neuronal activity assays and related kits.

Date PUBLISHED

  • 02/21/2019

Published Patent Application

  • WO2019/035034

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