Gut Microbiome Function Predicts Response to Anti-Integrin Biologic Therapy in Inflammatory Bowel Diseases

Application No.
PCT/US2018/031793
Broad Case No.
BI-10196
Inventors

Ashwin Ananthakrishnan, Chengwei Luo, Ramnik Xavier, Vijay Yajnik

Abstract

The present invention relates to a relationship between microbial metagenomic structure and function and clinical remission with anti-integrin therapy induction; longitudinal trajectory of changes in the microbiome with maintenance treatment; and a comprehensive predictive model incorporating clinical and microbiome-related data to accurately classify treatment response.

Date Published
Published Patent Application
WO2018/208910
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