Compositions and methods for treating drug-tolerant glioblastoma
Broad Case No.
List of inventors -
The present invention provides compositions and methods for the treatment of drug-tolerant glioblastoma, and in particular gliobastoma stem cells. Specifically, the methods comprise contacting a glioblastoma stem cell with a platelet-derived growth factor receptor alpha inhibitor and one or more of a histone lysine demethylase inhibitor and a Notch inhibitor.