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Assays For Massively Combinatorial Perturbation Profiling In Vivo

Application No.

PCT/US2018/064553

Broad Case No.

BI-10189

List of inventors -

Atray Dixit, Aviv Regev, Orit Rozenblatt-Rosen

Abstract

The present disclosure provides compositions, systems, and methods for pooled screening of perturbations correlating to a phenotype. The present disclosure also provides for methods of in vivo perturbation screening. The present disclosure also provides for high-throughput sample multiplexing. The present disclosure also provides for methods to determine the clonal effects associated with millions of genetic perturbation combinations using standard pooled screening reagents.

Date PUBLISHED

  • 06/13/2019

Published Patent Application

  • WO2019/113499

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