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Antibodies, compounds and screens for identifying and treating cachexia or pre-cachexia

Application No.

PCT/US2016/037012

Broad Case No.

BI-2015/073

List of inventors -

Todd Golub, David Thomas

Abstract

The invention provides therapeutic, engineered protein/peptide compositions comprising e.g., RAGE antibodies, T-cell receptors to target a RAGE receptor (including soluble forms thereof) directly and/or via differential competition with one or more pre-cachexia and/or cachexia-associated RAGE ligands or markers.

Date PUBLISHED

  • 12/15/2016

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