Job Opportunities in the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease
We are seeking highly motivated postdoctoral scholars and staff scientists to join a new joint project between laboratories at the Broad Institute and Danish universities to build a Human Gene Regulation Map, as part of the new NNF Center for Genomic Mechanisms of Disease.
This new effort will seek to build comprehensive maps of gene regulation in the human genome as a resource for uncovering biological mechanisms on common genetic diseases, with an initial focus on cell types relevant to cardiometabolic diseases including type 2 diabetes. We aim to combine recent advances in genomics, molecular biology, single-cell analysis, and stem cell models with approaches in computational biology and machine learning to identify fundamental rules of gene regulation.
| Position | Description |
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Demontis Group Contact: Ditte Demontis ditte@biomed.au.dk |
The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in the field of genetics and functional genomics of metabolic disorders, joining the research group of Professor Ditte Demontis, at Biomedicine, Aarhus University and the the Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, at Broad Institute. The appointed candidate will perform statistical analyses of large-scale genetic datasets of metabolic diseases and work intensively with existing and new methods to integrate genetic findings with large-scale functional genomics data e.g. transcriptomics (including single cell RNA- and spatial transcriptomics), epigenetic and proteomic data sets, to identify underlying disease mechanisms of metabolic disorders. Especially integration with single cell sequencing data to identify affected cell types and states will be in focus. Application deadline is 5th of June. |
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Contact: Melina Claussnitzer melina@broadinstitute.org |
The Claussnitzer lab is seeking a postdoctoral associate to join their Variant-to-Function (V2F) team. This individual will play an essential role in the team's efforts to advance the translation of metabolic diseases genetics into an understanding of underlying molecular and cellular disease mechanisms and identification of actionable therapeutic hypotheses. |
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Contact: Melina Claussnitzer melina@broadinstitute.org J.T. Neal |
The Claussnitzer/Neal labs are seeking a postdoctoral associate to join their Variant-to-Function (V2F) team. This individual will play an essential role in the team's efforts to advance the translation of metabolic diseases genetics into an understanding of underlying molecular and cellular disease mechanisms and identification of actionable therapeutic hypotheses. |
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Contact: Kasper Lage |
The Lage Lab is seeking a research scientist who will work to generate protein interaction networks that inform about pathways involved in disease and of high relevance to therapeutic development. Success in this role will require that the research scientist works closely with computational biologists and external partners to relate experimental findings to known biological principles in human cell lines. |
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Experimental Postdoctoral Associate Contact: Kasper Lage |
The Lage Lab is seeking an experimental postdoctoral associate to join the NNF Center for Genomic Mechanisms of Disease and help build the Human Gene Regulatory Map. The ideal candidate will work across disciplines and in collaboration with multiple groups at the Broad Institute and elsewhere to generate transcriptomic, epigenomic, and cell-type-specific proteomic datasets to derive fundamental insights into disease mechanisms. |
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Contact: Jesse Engreitz |
We are seeking a highly motivated research associate to join a new team at the Broad Institute to build a Human Gene Regulation Map. This effort will seek to understand the fundamental wiring of the noncoding genome and build a reference map for uncovering biological mechanisms on common genetic diseases, with an initial focus on type 2 diabetes and obesity. Key investigators involved: Jesse Engreitz, Melina Claussnitzer, Ray Jones and Kasper Lage. The successful candidate will apply technologies combining CRISPR, single-cell measurements, and epigenomic tools in human cells to understand gene regulation in health and disease. |
