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Joel Hirschhorn, institute member and co-director of the Metabolism Program at the Broad Institute and professor of pediatrics and genetics at Harvard Medical School and Boston Children’s Hospital, sits down with BioLogic to talk about how the research community has approached genome-wide association studies (GWAS) from concept to execution through the last decade.

Genome sequencing may someday become a routine part of medical care, but questions still surround best practices for returning genetic information to patients in a way that will optimally impact their health. Geneticists Robert Green and Heidi Rehm explain their research into developing such protocols, the benefits and risks inherent in providing genetic information, and the uncertain future of legal protections against genetic discrimination.