News from the Broad

The Broad Institute is committed to open sharing not only of its scientific data and tools, but also information and news about our progress towards achieving our mission. Below are just a few highlights from the Broad scientific community.
  • Taking aim at rare cancer variants

    July 28th, 2016
    With a systematic look at function, Broad’s Target Accelerator effort proves that even rare mutations can drive cancer
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  • New approach speeds chemical library screens

    July 18th, 2016

    It can take a year or more for a chemical library to be screened in cells, a delay that often slows chemists’ access to biological data that could help them plan their synthesis efforts. In the Journal of the American Chemical Society last week, a team led by Stuart Schreiber and Zarko Boskovic, of Broad’s Center for the Science of Therapeutics and Harvard University’s Department of Chemistry and Chemical Biology, shares an approach for screening newly synthesized compounds’ biological activity in near real-time. Combining chemical synthesis and cell painting, the approach could make the library design process more nimble, reveal how certain synthesis steps impact molecules’ biological activities, and accelerate drug candidate discovery.

  • Microbiome genes on the move

    July 14th, 2016
    Largest metagenomic view of the developing world uncovers “mobile genes” that reveal how culture shapes the human microbiome The word “culture” typically refers to a group’s shared heritage – such as its customs, cuisine, music, and language – that connects people in unique ways. But what if culture extended to a population’s microbiome – the collection of microorganisms that live on and...
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  • Genetics of type 2 diabetes revealed in unprecedented detail

    July 11th, 2016
    The largest study of its kind into type 2 diabetes has produced the most detailed picture to date of the genetics underlying the condition. More than 300 scientists from 22 countries collaborated on the study, which analysed the genomes of more than 120,000 people with ancestral origins in Europe, South and East Asia, the Americas and Africa.
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  • Vanderbilt, working with Verily and Broad Institute, receives grant award from NIH Precision Medicine Initiative to drive data collection, storage, and analysis

    July 7th, 2016
    The National Institutes of Health (NIH) Precision Medicine Initiative Cohort Program has awarded a five-year grant to develop a data platform for collecting, curating, securely storing, and sharing a wide range of health data from a planned million volunteers. The Data and Research Support Center for the project will be led by Vanderbilt University School of Medicine working with Broad Institute of MIT and Harvard, Verily Life Sciences and...
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