Contrary to popular belief, tumors don’t develop undisturbed. They undergo almost constant immune attack — which, as a result, changes their mutational composition. But just how this immune response is initiated and its effect on different tumor types has remained largely unexplored…until now. For the first time, a team of researchers from the Broad — including Mike Rooney, Sachet Shukla, Cathy Wu, Gad Getz, and Nir Hacohen — has performed a systematic survey of how 18 different tumor types induce and adapt to immune responses. Read all about it in Cell.
News-in-brief / 01.16.15