Survey of brain cell junctions shows striking similarities between schizophrenia and bipolar disorder
An unbiased protein analysis comparing synapses from people with the disorders uncovers shared patterns.
Support for this research was provided by the Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard.
Aryal S, et al. Deep proteomics identifies shared molecular pathway alterations in synapses of patients with schizophrenia and bipolar disorder and mouse model. Cell Reports. Online May 11, 2023. DOI: 10.1016/j.celrep.2023.112497.