Schizophrenia gene mutation causes many changes in the mouse brain
A study of a genetic mouse model of schizophrenia supports two long-debated hypotheses, and unveils additional new clues about the biological roots of the disorder.
This work was supported in part by the Stanley Family Foundation, the Institute for Basic Science, and the Max Planck Society.
Farsi Z, et al. Brain region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice. Neuron. Aug 31, 2023. DOI: 10.1016/j.neuron.2023.08.004.